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6 results on '"C. Tzanno"'

1. Total lymphoid irradiation for pretransplant immunosuppression and recurrence of focal segmental glomerulosclerosis

Author

R. C. Villar, Dewton de Moraes Vasconcelos, Alberto José da Silva Duarte, Wladimir Nadalin, Luiz Estevam Ianhez, C. Tzanno-Martins, and Pedro R. Chocair

Subjects
Adult, Immunosuppression Therapy, Male, Transplantation, Pathology, medicine.medical_specialty, Lymphatic Irradiation, Glomerulosclerosis, Focal Segmental, business.industry, medicine.medical_treatment, Immunosuppression, Total lymphoid irradiation, Middle Aged, medicine.disease, Text mining, Focal segmental glomerulosclerosis, Recurrence, Preoperative Care, medicine, Humans, Female, business
Published
2008
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2. Restoration of impaired T-cell proliferation after parathyroidectomy in hemodialysis patients

Author

A.J.S. Duarte, C. Tzanno-Martins, E. A. Futata, and Vanda Jorgetti

Subjects
Parathyroidectomy, Adult, medicine.medical_specialty, Cellular immunity, endocrine system diseases, medicine.medical_treatment, T cell, T-Lymphocytes, Urology, Parathyroid hormone, macromolecular substances, Renal Dialysis, Internal medicine, medicine, Humans, Phytohemagglutinins, Hyperparathyroidism, B-Lymphocytes, business.industry, medicine.disease, medicine.anatomical_structure, Endocrinology, Immunoglobulin M, Pokeweed Mitogens, Parathyroid Hormone, Immunoglobulin G, Interleukin-2, Secondary hyperparathyroidism, Female, Hemodialysis, business, hormones, hormone substitutes, and hormone antagonists, Cell Division, Kidney disease
Abstract

Background/Aims: Severe secondary hyperparathyroidism is not infrequent in hemodialysis patients and recent studies suggest that parathyroid hormone (PTH) may play a role in the genesis of cell immunity abnormalities in uremia. The aim of the present study is to describe the effect of parathyroidectomy on T- and B-cell functions in hemodialysis patients. Methods: The study was performed on 6 patients with severe secondary hyperparathyroidism. iPTH, B, CD4+, CD8+, total number of lymphocytes, lymphoproliferative response to PHA, PWM and Candidin, and IgG, IgM, IL-2 production in vitro were determined 1 day before and 4 months after parathyroidectomy. Results: The lymphoproliferative response to PHA increased significantly after parathyroidectomy. We also observed a trend to an increase in production of IgG and IgM after PWM stimulation before therapy. Conclusion: The present study suggests that patients with extremely high levels of PTH show a complete restoration of impaired T-cell proliferation after parathyroidectomy.

Published
2000

3. Immunomodulatory effects of vitamin D analog KH1060 on an experimental skin transplantation model

Author

Alberto José da Silva Duarte, D. L. Bertolini, P Araújo, R.N.C Silva, and C. Tzanno-Martins

Subjects
Male, medicine.medical_specialty, medicine.medical_treatment, Monocytes, Immunophenotyping, Mice, Animal model, Calcitriol, Internal medicine, medicine, Vitamin D and neurology, Animals, Transplantation, Homologous, Lymphocytes, Transplantation, Chemotherapy, business.industry, Biological activity, Vitamina d, Skin Transplantation, Flow Cytometry, Skin transplantation, Antigens, Differentiation, Mice, Inbred C57BL, Endocrinology, Mechanism of action, Mice, Inbred CBA, Vitamin D Analog, Surgery, medicine.symptom, business, Immunosuppressive Agents
Published
1999

4. The role of experimental aluminum intoxication in allogeneic immunoresponse

Author

C. Tzanno-Martins, Marcello Marcondes, Marcia Cianga Tanji, M.M Tanji, Alberto José da Silva Duarte, Luiz Sergio Azevedo, and Emil Sabbaga

Subjects
Male, medicine.medical_specialty, Lymphocyte, medicine.medical_treatment, Spleen, Lymphocyte Activation, Immune system, Internal medicine, Rats, Inbred BN, medicine, Animals, Heart transplantation, Transplantation, biology, business.industry, In vitro, Rats, medicine.anatomical_structure, Endocrinology, Concanavalin A, Rats, Inbred Lew, Immunology, biology.protein, Heart Transplantation, Lymphocyte Culture Test, Mixed, business, Immunoresponse, Aluminum
Abstract

To evaluate the immunological properties of aluminum (Al) in experimental Al intoxication in rats, we performed heart transplantation and in vitro experiments. Lewis (Lew) rats were intoxicated with intraperitoneal injections of AlCl3. Heart transplants were performed using Brown-Norway (BN) rats as donors. Isotransplants and normal Lew were used as controls. No differences in survival were observed. Unidirectional mixed lymphocyte cultures (MLC) and Concanavalin A (Con A)-stimulated cultures were prepared using spleen cells from normal and Al-intoxicated Lew rats. No differences were found in unidirectional MLC. Intoxicated cells showed a less intense response to Con A than did normal cells. In conclusion, we could not detect an immunosuppressive role of Al intoxication in experimental cardiac transplantation or in MLC. However, the depressed Con A blastogenic response of Al-intoxicated cells may reflect an immunological role yet to be defined.

Published
1995

5. Protein-energy wasting, inflammation and oxidative stress in CKD 5D

Author

L. Rosales, O. Vega, L. Usvyat, S. Thijssen, N. Levin, P. Kotanko, T. Miyamoto, A. Witasp, A. Rashid Qureshi, O. Heimburger, P. Barany, L. Nordfors, B. Lindholm, P. Stenvinkel, J. Jesus Carrero, M. Kalousova, H. Benakova, A. A. Kubena, S. Dusilova-Sulkova, V. Tesar, T. Zima, Y. J. Lee, M. S. Kim, B. G. Song, S. Cho, S. R. Kim, M. Stockler-Pinto, J. Lobo, C. Moraes, A. Barros, N. Farage, G. Boaventura, D. Mafra, O. Malm, S. Matsuda, N. Akaike, K. Kajiwara, D. Tovbin, S. Kesari, D. Sola-Del Valle, J. Barasch, A. Douvdevani, M. Zlotnik, A. Abd Elkadir, S. Storch, M. Sarikaya, F. Sari, J. Gunes, M. Eren, R. Cetinkaya, J.-C. Hwang, T.-L. Ma, C.-T. Wang, H. Ogawa, T. Nagaya, Y. Ota, M. Sarai, O. Oda, B. Biavo, C. Uezima, M. E. Costa, C. Barros, J. P. Martins, E. Ribeiro Jr, C. Tzanno-Martins, H. Honda, N. Kimata, K. Wakai, T. Akizawa, J. Droulias, V. Filliponi, C. Argyropoulos, R. Fischer, C. Papakonstantinou, C. Papadopoulos, A. Kouvelis, G. Zervas, E. Dampolia, N. Zerefos, D. Valis, C. Sarcina, I. Baragetti, P. Uboldi, L. Buzzi, K. Garlaschelli, F. Ferrario, V. Terraneo, G. D. Norata, A. L. Catapano, C. Pozzi, G. Conti, D. Santoro, D. Caccamo, S. Condello, D. Pazzano, V. Savica, R. Jentile, C. Fede, G. Bellinghieri, R. Zortcheva, V. Ikonomov, B. Galunska, D. Paskalev, D. Dobreva, D. Ivanova, M. Tsunoda, R. Ikee, N. Sasaki, N. Sato, N. Hashimoto, L. Korol, I. Dudar, L. Migal, Y. Gonchar, I. Seleznova, V. Ischenko, M. Erkmen Uyar, E. Tutal, Z. Bal, N. Ahmed, S. Sezer, D. Fedak, M. Kuzniewski, D. Pawlica, B. Kusnierz-Cabala, B. Solnica, M. Drozdz, K. Janda, W. Sulowicz, J. Kopec, M. Banach, and V. Leal

Subjects
Transplantation, medicine.medical_specialty, Endocrinology, Nephrology, business.industry, Internal medicine, medicine, Inflammation, Protein energy wasting, medicine.symptom, medicine.disease_cause, business, Oxidative stress
Published
2011
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6. Efficiency of Total Lymphoid Irradiation Plus Immunosupressants Pre-Renal Transplant in Focal Segmental Glomerulosclerosis: Clinical and Laboratorial Analysis

Author

Alberto José da Silva Duarte, Dewton de Moraes Vasconcelos, R.C. Villar, W. Nadalin, Pedro R. Chocair, C. Tzanno-Martins, and Luiz Estevam Ianhez

Subjects
Cancer Research, Pathology, medicine.medical_specialty, Radiation, Focal segmental glomerulosclerosis, Oncology, Renal transplant, business.industry, medicine, Radiology, Nuclear Medicine and imaging, Total lymphoid irradiation, medicine.disease, business
Published
2005
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