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This chapter introduces the main topics of research that have benefited so far from the space environment (reduced gravity, ambient radiation, vacuum, etc.), and provides an outlook for future research development. By convention, it is split into two fields: physical sciences/engineering and life sciences.

costly. The key is therefore to establish an accurate assessment of the victim’s state and this is currently tributary to the presence onboard of a medical doctor and equipment. We propose in this contribution a network trac model for the deployment of an inight, satellite based telemedicine service. The purpose of the terminal is to support accurate remote assessment using a cabin crew member as operator. This contribution also includes an estimation of the network resources required for running the service.

The general health issues considered in two scenarios of human long-term exploratory missions, which include a mission to a lunar base and a mission to Mars, have been analysed. Based on statistical data from occupational and normal population groups of Western countries, the following safety objectives have been chosen: individual risk of death by illness (=natural death) during the mission shall be −3 /year, that by injury (=accidental death) −4 /year, and that from all causes, including spacecraft failure (taken from most exposed professions) −2 /year. Using the classical reliability requirements for human space missions, reliability objectives have been set for each mission scenario, resulting in values compatible with the mission safety objectives. The main results are as follows: (i) based of the probability of occurrence of diseases and injuries and on the constraints imposed by exploratory mission scenarios, the crew shall have a full autonomy in terms of medical and surgical diagnostics and care means and competency; (ii) the control of the toxic and biological risks in a confined environment for a so long exposure shall be carefully analyzed and the technical solutions shall master these risks; (iii) the state of the art shows that bone loss during the long stay in weightlessness, especially during missions to Mars, remains an unacceptable risk. Solutions to control and to prevent this risk shall be developed; (iv) the control of human physical capacity impairment under weightlessness shall be optimised. A roadmap in the field of health care has been elaborated for a future European participation strategy towards human exploratory missions taking into account preparatory activities, such as analogue situations and ISS opportunities, and potential terrestrial applications and benefits.