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Background: There is an increasing demand for minimally invasive aortic valve replacement. This study aimed to investigate the safety and feasibility of minimally invasive aortic valve replacement through a right parasternal second intercostal transverse incision. Methods: This was a retrospective study, and we collected information from 111 patients who underwent isolated aortic valve replacement surgery performed by the same surgeon from January 2018 to December 2019. According to the operative approach, the patients were divided into a sternotomy aortic valve replacement (SAVR) group (n = 62) and a minimally invasive aortic valve replacement (Mini-AVR) group (n = 49). We compared the intraoperative and postoperative data between the two groups. Result: There was no difference in preoperative data between the Mini-AVR and SAVR. The postoperative ventilator-assisted time, CSICU time and postoperative hospital stay of the Mini-AVR were shorter than those of the SAVR [(15.45 ± 5.75) VS (18.51 ± 6.71) h; (1.77 ± 0.31) VS (2.04 ± 0.63) d; (8.69 ± 2.75) VS (10.77 ± 2.94) d], and the difference was statistically significant (P

Objectives: An increase in the trimethylation of lysine 4 of histone 3 (H3K4me3) has been reported to be involved in the development of several types of tumors. However, the level and role of H3K4me3 in human esophageal cancer (HEC) remain unknown. Here, we assessed the role and clinical significance of H3K4me3 in HEC. Methods: The level of H3K4me3 was determined in 15 pairs of HEC and paracancerous tissues by Western blotting. A tissue microarray including samples from 100 HEC patients was analyzed by immunohistochemistry to determine the relationship between the level of H3K4me3 and the clinicopathological features of HEC patients. Then, the levels of H3K4me3 in HEC cells were elevated via knockdown of inhibitor of growth family member 4(Ing4) expression. Finally, the prognostic significance of H3K4me3 levels in HEC patients was further analyzed. Results: We found that H3K4me3 levels were frequently elevated in HEC tissues compared with adjacent esophageal tissues, and elevated H3K4me3 was significantly associated with poor tumor differentiation (p =1.39×10-5) and advanced tumor stage (p=8.5×10-5). After Ing4 knockdown in HEC cells, we found that the cell proliferation, metastasis, invasion and colony formation abilities were enhanced compared to those in the control cells. Notably, we found that HEC patients with a high level of H3K4me3 exhibited an unfavorable 5-year survival rate compared to those with a low level of H3K4me3 (p=6.8×10-5). The univariate analysis showed that the tumor differentiation, TNM stage, and H3K4me3 level were predictors of the overall survival rate of HEC patients. In the multivariate analysis, tumor stage (p=0.015) and H3K4me3 level (p=0.034) were revealed to be independent parameters for predicting the prognosis of HEC patients. Conclusions: Thus, high levels of H3K4me3 may be used as a meaningful biomarker for HEC prognosis evaluation.

Idiopathic pulmonary arterial hypertension (IPAH) is a rare vascular disease with a poor prognosis, and the mechanism of its development remains unclear. Further molecular pathology studies may contribute to a comprehensive understanding of IPAH and provide new insights into diagnostic markers and potential therapeutic targets. Iron deficiency has been reported in 43-63% of patients with IPAH and is associated with reduced exercise capacity and higher mortality, suggesting that dysregulated iron metabolism may play an unrecognized role in influencing the development of IPAH. In this study, we explored the regulatory mechanisms of iron metabolism in IPAH by bioinformatic analysis. The molecular function of iron metabolism-related genes (IMRGs) is mainly enriched in active transmembrane transporter activity, and they mainly affect the biological process of response to oxidative stress. Ferroptosis and fluid shear stress and atherosclerosis pathways may be the critical pathways regulating iron metabolism in IPAH. We further identified 7 key genes (BCL2, GCLM, MSMO1, SLC7A11, SRXN1, TSPAN5, and TXNRD1) and 5 of the key genes (BCL2, MSMO1, SLC7A11, TSPAN5, and TXNRD1) as target genes may be regulated by 6 dysregulated miRNAs (miR-483-5p, miR-27a-3p, miR-27b-3p, miR-26b-5p, miR-199a-5p, and miR-23b-3p) in IPAH. In addition, we predicted potential IPAH drugs—celastrol and cinnamaldehyde—that target iron metabolism based on our results. These results provide insights for further definition of the role of dysregulated iron metabolism in IPAH and contribute to a deeper understanding of the molecular mechanisms and potential therapeutic targets of IPAH.

Background Circulatory arrest has been identified as an independent risk factor related to postoperative mortality in patients with Stanford type A aortic dissection. This study described a modified technique for distal aortic arch occlusion that markedly shortened the circulatory arrest time. The early results are encouraging. Methods From May 2016 to September 2018, 51 patients with Stanford type A aortic dissection underwent the modified procedure for aortic arch replacement. All operations were performed via transitory circulatory arrest by clamping the distal aorta between the left common carotid artery and the left subclavian artery. The in-hospital and follow-up data of the treated patients were investigated. Results Successful repair of the involved vasculature was achieved in all patients. One (1) patient died due to postoperative aspiration and infection, and three patients required continuous renal replacement therapy due to poor preoperative renal function. The remaining patients were successfully discharged. The median average circulatory arrest time was 5.0 (3.0–6.0) minutes. No cases of tracheotomy, delayed closure, secondary thoracotomy, or other complications occurred. During the follow-up period of 2.4–18.6 months, the implanted grafts and stented elephant trunks were all fully open and not kinked. Conclusions A modified distal aortic arch occlusion can considerably shorten the duration of circulatory arrest. Current experience suggests that this approach can serve as a feasible alternative for patients during aortic arch replacement because of its simplicity and satisfactory clinical effects.

Pancreatic adenocarcinoma (PDAC) is known to have a poor prognosis partly because of lack of effective biomarkers. In the test set, we investigated dysbindin (DTNBP1) as a potential biomarker for PDAC by comparing preoperative and postoperative serum mass spectrometry (MS) proteomic profilings. Of the included 50 PDAC patients, 42 (positivity of 84.0%) detected a lower MS peak in postoperative serums than preoperative ones which was then identified as dysbindin. In the verification set, receiver operating characteristics (ROC) were used to assess diagnostic efficiency. 550 participants were included in the verification set [250 with PDAC, 80 with benign biliary obstruction (BBO), 70 with chronic pancreatitis (CP) and 150 healthy donors (HD)]. Dysbindin was increased in PDAC patient sera than in all controls. ROC curves revealed the optimum diagnostic cutoff for dysbindin was 699.16 pg/ml [area under curve (AUC) 0.849 (95% CI 0.812-0.885), sensitivity 81.9% and specificity 84.7%]. Raised concentration of dysbindin in sera could differentiate PDAC from BBO, CP and HD. Moreover, dysbindin maintained its diagnostic accuracy for PDAC patients who were CA19-9 negative [AUC 0.875 (95% CI 0.804-0.945), sensitivity 83.0%, specificity 89.0%] and for patients with benign biliary obstruction [AUC 0.849 (95% CI 0.803-0.894), sensitivity 82.3%, specificity 84.0%].Our discovery of dysbindin may complement measurement of CA19-9 in the diagnosis of PDAC and help to discriminate PDAC from other pancreatic diseases or begin biliary obstruction.

Lateral pressure coefficient is an important parameter in geological engineering, and it influences significantly the damage zone around boreholes. In accordance with the fundamental principles of the Particle Flow Code (PFC), various models were established to investigate the crack propagation patterns and energy evolution rules of coal in disturbed zones of hydraulic slotting for various lateral pressure coefficients. Cracks around a slotted borehole propagate in the horizontal direction when the lateral pressure coefficient λ is less than 1, distribute uniformly when λ is equal to 1, and extend mostly in the vertical direction when λ is greater than 1. The total number of cracks increases linearly with λ. The variation in kinetic energy for coal failure was recorded; kinetic energy evolution observes a similar rule and its process can be divided into four stages, namely, the quick-release, rapid dissipation, drastic fluctuation, and stabilized stages. The peak value of the kinetic energy increases linearly with λ. The acoustic emission events distribute discretely when λ is small and uniformly when λ is equal to 1. The variation in acoustic emission events tends to increase sharply before decreasing when λ is greater than 1. The research findings are significant to the exploration of pressure relief mechanisms for hydraulic slotting from a microcosmic perspective.

With the development of computer technology, networking and information technology, and the requirements for the continuous improvement of living, enjoying smart household life has become possible, and become the inevitable tendency. This paper introduces a kind of smart home control system which based on 32-bit embedded processor ARM platform and the ZigBee wireless network communication technology. This system was designed to aim at the ordinary residential district family user, which can realize the concentration supervisory control and management to the housing safe condition, and achieve the household electrical appliances' remote control.

According to the characteristics and the application background of the intelligent home, designs the multi function control system of a family. The system uses Freescale i.MX51 processor Carle company ARM Cortex series A8 as MCU, the embedded Linux as the software development platform, and design a friendly user interface based Qt technology, realizes the ARM plate of each function module and server interaction. System with digital video intercom, messaging, appliance control, security alarm, home entertainment and other functions.

Taking an immune operator added to the framework of the genetic algorithm, individuals vaccinated to further enhance the survival ability of the individual, the immune genetic algorithm as a set of immune mechanisms and evolutionary mechanisms in one of the new evolutionary algorithm is applied to reverse genome rearrangement problem is a new attempt, the genetic algorithm can be avoided premature shortcomings, while the immune genetic algorithm parallelization can improve convergence speed.

Vegetable soybean is a kind of value-added specialty soybean serving as vegetable or snacks. Understanding the genetic structure of vegetable soybean is a key point for further utilization in breeding programs. In the present study, the genetic structure and diversity of 100 vegetable soybean accessions planted in China was analyzed using 53 simple sequence repeat (SSR) markers. A total of 296 alleles were detected with an average of 5.6 alleles per SSR locus. The polymorphism information content (PIC) values of SSR markers ranged from 0.074 to 0.831, with an average of 0.573. Nei’s genetic distance between accessions ranged from 0 to 0.9434 with an average of 0.6286. These vegetable soybean germplasms could be divided into 8 subgroups based on STRUCTURE analysis, or 11 subgroups based on unweighted pair group method with arithmetic average (UPGMA) cluster. Further comparison showed that the UPGMA subgroups and STRUCTURE subgroups were in fact highly consistent. Germplasms in each classified groups showed great consistency with their origins, seed coat colors or pedigrees. Genetic relationships among germplasm panels that initially came from different geographical regions were also analyzed. Germplasm panels from China Mainland, Taiwan Island and Japan were highly similar to each other with the similarities of over 98 %. Molecular data and cluster analysis also showed that germplasms from China Mainland are more diverse than those from other areas. These results gave us a deep insight into the genetic structure of vegetable soybeans in China and will help us to improve the breeding strategies.

Point bar reservoir is the key development object in the late stage of oilfield development at present. In this paper, numerical simulation is done on the basis of the point bar architecture in the modeling of the point bar. Through dynamic data generating simulated well history and acquiring X-unit splitting factor, history matching is done on this basis. The numerical simulation results reveal that oil saturation has belt distribution characteristics on the pane due to the lateral accretion interlayer affect to the oil-water displacement; injection wells transverse spread is limited by the lateral accretion interbed control; by lateral accretion interlayer updip pinchout control, the remaining oil is mainly located in the middle and upper part of the lateral accretion [1,2]. Because of the above characteristics, taking horizontal wells to develop the top remaining oil of point bar has been very good results. And it has been confirmed by the further results of the numerical simulation.

Types of found reservoirs and its distribution characteristics of Putaohua oil layer in the Sanzhao Sag were analyzed. The controlling factors of hydrocarbon distribution were investigated. Sanzhao Sag is Sag-wide oil-bearing, but its distribution of oil and water is extremely complicated. The reservoir types are mainly fault block reservoirs, low amplitude structure reservoirs, fault-lithologic reservoirs and lithologic reservoirs. The distribution of reservoirs is mainly controlled by three geological factors: first, long-term inherited nose-like structure is predominant direction of petroleum migration; it induced oil and gas migration at a critical period of hydrocarbon accumulation and formed oil-gas accumulation area. Second, fault across main-line of hydrocarbon migration and high angle skew plug off hydrocarbon, and its side adjacent to Sag is a large number of hydrocarbon accumulation areas. Third, multi-fault region can easily form a fault (-lithological) reservoir accumulation area in the slope of sag.

This paper takes X block as the target area, on the basis of logging data, the core information, dynamic production information, with high-resolution sequence stratigraphy demonstrating two-separability of PI33systematically from the angle of sedimentology, namely, this layer is a sedimentary complex of the two river stage. We have analyzed the characteristics of remaining oil in the compound sandbody. Each channel sandbody has its own respective characteristics in the vertical water flood. As a whole at the bottom, the extent of water flood is high, and it weakens gradually until non-flooded with the level raising. It provided the basis for the study of the single sandbody architecture and the advance of the recovery ratio.

Introduced a kind of device controlling function switches of induction cooker, which is suitable for hot pot heating situation, using wireless control which belongs to the induction technology. A wireless transmitter sends the control signal wirelessly and the built-in wireless receiver receives the signal, which conveniently and practically avoids the operation depending on touch with feeling or lifting the tablecloth off to speak directly to the induction cooker. At the same time, the wireless transmitter is fixed by a dedicated lock onto the pot ear, facilitating not only the operation of the user, but also the removal when cleaning.

Sweetpotato (Ipomoea batatas) ranks as the seventh most important staple crop in the world and the fifth in developing countries after rice, wheat, maize and cassava. Sweetpotato is mainly grown in developing countries, which account for more than 95% of total production of the whole world. Genetic resources, including cultivated varieties and wild species, are a prerequisite for novel sweetpotato breeding in both conventional and genetic engineering programs. Various cryopreservation protocols have been developed for shoot tips and embryogenic tissues. The former explants are preferred for long-term conservation of sweetpotato genetic resources, while the latter are valuable for sweetpotato genetic improvement. This review provides update comprehensive information on cryopreservation of sweetpotato shoot tips and embryogenic tissues. Plant pathogens such as viruses and phytoplasma severely hamper high yield and high quality production of sweetpotato. Thus, usage of pathogen-free planting materials is pivotal for sustainable sweetpotato production. Cryotherapy of shoot tips can efficiently eradicate sweetpotato pathogens such as viruses and phytoplasma. The mechanism behind pathogen eradication by cryotherapy of shoot tips has been elucidated. Pathogen eradication by cryotherapy provides an alternative, efficient strategy for production of pathogen-free plants. In addition, cryopreserved tissues may also be considered to be safer for exchange of germplasm between countries and regions.

In order to research the influence between air return tunnel and dedicated gas emission tunnel to arrange the tunnels properly, numerical experimental model is established according to the exploitation technical conditions and mechanical properties of rocks of 32020 working face in Pingmei NO.5 mine. FLAC3D is used to analysis the stress distribution among air return tunnel and dedicated gas emission tunnel with different interval thus confirm the most appropriate interval. By simulating the impact of gob to the tunnels, fully caving of the gob is helpful to reduce the outburst risk of coal and rock can be obtained. Variation of vertical stresses in two situations (dedicated gas emission tunnel driving along and air return tunnel driving first) is simulated respectively, thus obtain the safe distance of air return tunnel driving ahead. Research results can provide theoretical basis to control stress concentration, ensure emission efficiency and reduce tunnel construction so as to make safe and fast driving come true.

View of the high stress, high gas coal seam characteristics and the current process of regional gas control problems, regional gas control method, based on drilling-blasting-fracturing-extracting integration technology were investigated by theoretical research, numerical simulation and field testing. Composite sealing technology has been carried out in the domestic relevant mine. The application results show that the technique obviously enhance the drill effective range, reduced the quantity of drills, shortened the gas extraction time and eliminated the outburst risk of coal mines which implied a broad industrial application prospect.

The hydro-fracturing technology is the depressurization antireflection elimination outburst technology for the low permeability outburst coal seam with high methane. At present, the mechanism of the depressurization antireflection elimination outburst is sufficiently mastered and the application effectiveness of field engineering also is well, but how to determine hydro-fracturing parameters is not systematically described, especially the reasonable water pressure. Based on the hydro-fracturing mechanism and process, the reasonable water pressure is theoretically analyzed, and then the pressure parameter of hydro-fracturing applicated in the low permeability outburst coal seam with high methane is obtained, finally the reasonable pressure formula of water injection is obtained. The application test results of field engineering shows that there is the difference between the theoretical analysis result and the pressure in field engineering test, namely, the theoretical analysis pressure is lower than the pressure in field engineering test.

In recent times, with the development of protection stratum, it is more and more important to investigate its effects. In this paper, in view of this situation, similar simulation experiment and site test are used to investigate the real-time effects at a certain mine of Pingdingshan Coal Group Company. The results of similar simulation experiment and site test show the stress and displacement variation of overlying rock and protected seam; define the max relative deformation and Roof Falling Interval; and determine the Protected Zone and Pressure Relief Angle. So, the result of research has great significance in directing the production of the mine and in developing the technology of protection stratum mining.

Based on the experiment, the important influence of the pipe with abnormal structure on gas explosion propagation characteristics is analyzed. The results show that gas explosion propagation at the turning point is a process of interaction of pressure wave, flame and complicated flow field. The overpressure of pressure wave and flame transmission velocity are rapidly accelerated and the pipe wall at the turning point is seriously destroyed. The angle of bend has a great influence on the gas explosion propagation characteristics, i.e. there is a different degree of change in both flame velocity and pressure wave overpressure value when gas explosion propagates through bend with different angles. The bend not only increases the turbulent flow of combustion area that accelerates the reaction and velocity, but also enlarges the resistance and heat transmission to the pipe wall. At the same time, the expansion wave at the turning point restrains the gas explosion propagation. The influence of bend on gas explosion propagation characteristics is determined by the combined impact of inhibitor factors and motivation factor. Experiment research and theory analysis indicate that gas explosion propagation characteristics in bend pipe are obviously different from that in straight pipe. So in the mine exploitation, the bend roadways should be decreased as few as possible, and preventive measures should be taken in order to diminish the loss caused by gas explosion. The research results will play an important role in the guidance of preventing gas explosion from occurring and alleviating the damage in coal mine.

Overburden rock movements and fracture developments occur during mining activities. Consequently, relief gas reservoirs and migration in coal seams being mined as well as in near distant coal seams appear. We considered a gas disaster management project and rules on stope relief of gas flows together and explored a gas reservoir and the evolution of stope surrounding rock fractures in the process of mining near distant protective layers by physical simulation, numerical simulation and field testing. Different techniques provide evidence of the rules of interaction of gas reservoirs and the evolution of surrounding rock fractures and are able to find accurately the gas-rich regions around the stope. Finally, we found that these rules can provide a basis for taking measures to prevent gas accidents in the protective layer of the coalface as well as for demonstrating and designing programs to drain high concentrations of gas from the gob.

Aimed at the actuality of coal mine risk management, this paper discussed the primary factors which affected technical support system of coal mine risk management, and established a technical support system of coal mine risk management to recognize and analyze risks during the process of coal production by using the method of risk management and system engineering based on the current safety problems of Pingdingshan Colliery Group . Meanwhile, we also developed a technical support system software of coal mine risk management and applied it in the technical support system of coal mine risk management in related mines. This system was able to make every risk in control and achieved good results and safe production.

In order to investigate the gas diffusion process in the coal seam, this paper simplifies the complex course into the capillary model and gets the motion differential equation when the gas diffusion obeys Fick’s law. Meanwhile, with the knowledge of differential equation and mathematic-physical equation, with the help of MATLAB as well, this paper obtains the analytic answer of the speed and flow rate of gas diffusion for the first time, which can supply more accurate quantized parameters to solve the gas problem in coal mine.

In order to explore the propagation law of gas explosion in bend laneways, the propagation laws of flame and shock wave in bend duct are theoretically and experimentally investigated. The results show that the stress of shock wave is complicated and the flame velocity changes complicatedly in the bend duct; besides, the propagation process of gas explosion in the bend duct is the mutual action of explosion wave, flame and complicated flow. The explosion wave overpressure and flame velocity increase sharply at bend, which destroyed the surface of bend location especially seriously. Therefore, in the mine exploitation and laneway design, the bend laneway should be avoided and the obstruction should be eliminated as possible. When the bend is unavoidable, the relevant preventive measures should be adopted to suppress the gas explosion propagation, depress the intensity and diminish the loss due to gas explosion.

In order to simulate field distribution rules, mathematical models for 3-D air flows and gas transfer in the goaf of the coal mining are established, based on theories of permeability and dynamic dispersion through porous media. A gas dispersion equation in a 3-D field is calculated by use of numerical method on a weighted upstream multi-element balance. Based on data of an example with a U type ventilation mode, surface charts of air pressure distribution and gas concentration are drawn by Graphtool software. Finally, a comparison between actually measured results in the model test and the numerical simulation results is made to proves the numerical implementation feasible.

In this paper, the variations in coalbed gas content, initial gas desorption property and coal strength after drilling-slotting integration technique and gas drainage were investigated by testing seven coal samples obtained from the coal seam #10 of Yangliu Coal Mine. The MICP and N2GA were combined to characterise the pore-size distribution. It is revealed that the residual coalbed gas content decreases substantially with the decrease in boreholes distances. Nevertheless, the variations in initial gas desorption velocity and coal hardiness coefficient represent an opposite tendency. In the microscopic aspect, the variation in pore-size distribution is notable. With the decrease in the boreholes distances, the adsorption pore proportion decreases and the seepage pore proportion increases. The drilling-slotting integration technique and gas drainage affect the aforementioned three macroscopic indices by changing the pore characteristics and moisture content. Besides, the guiding significance for field application of this technique is elaborated. [Received: March 1, 2015; Accepted: November 4, 2015]

White organic light-emitting diodes (WOLEDs) have attracted both scientific and industrial interest in the solidstate lighting and display applications due to their exceptional merits,such as high luminances,low power consumptions, high efficiencies,fast response times,wide-viewing angles,flexibilities and simple fabrications.The power efficiency of WOLED has been step-by-step improved in the last 20 years,however,the lifetime of WOLED is still unsatisfactory, which greatly restricts the further development of WOLED.In general,the tandem structure can be used to obtain high-efficiency and long-lifetime WOLED.One of the most important features of this kind of structure is that the different-colors emitting units can be connected by the charge generation layer.Therefore,the key to achieving a highperformance tandem device is how to design the charge generation layer.In this paper,we first develop a tandem green OLED by using an effective charge generation layer with an ultra-thin Ag layer between 4,7-diphenyl-1,10-phenanthroline:CsCO3 and hexaazatriphenylenehexacabonitrile,achieving high luminance,low voltage,high efficiency and long lifetime.The green tandem device with ultra-thin Ag layer (device C) obtains a highest luminance of 290000 cd/m2,which is 1.4 and 1.9 times higher than those of the tandem devices without ultra-thin Ag (device B) and singleunit device (device A),respectively.The driving voltage of device C is 7.2 V at 1000 cd/m2,1.4 V lower than that of device B.Besides,the maximum current efficiency of device C is 60.4 cd/A,which is 2.4% and 220% higher than those of device B (59 cd/A) and device A (18.7 cd/A),respectively.The power efficiency of device C is 26 lm/W,which is 21% higher than that of device B (21.5 lm/W).Moreover,the lifetime (T80) of device C reaches 250 h at an initial luminance of 10000 cd/m2,which is nearly 100 times higher than that of device B (2.7 h).Finally,we fabricate a white tandem device with the optimized charge generation layer,achieving a current efficiency and power efficiency of 75.9 cd/A and 36.1 lm/W at 1000 cd/m2,respectively.In addition,the lifetime (T80) is 77 h at an initial luminance of 10000 cd/m2.All the excellent performances are ascribed to the introduction of the ultra-thin Ag layer into the charge generation layer, which can effectively block the charge generation layer from diffusing.This exciting discovery can provide an effective way to design efficient and stable WOLED,which is beneficial to the solid-state lighting and display markets.

Light amplification due to two-beam coupling is realized in doped polymethyl methacrylate (PMMA) glasses. A coupling gain as large as 14 cm-1 is obtained. The dynamic behaviour of absorption and light-induced scattering due to the process of photopolymerization are also studied. The results show that the amplification and its dynamic process enable possible applications of PMMA in optical devices.

Forward degenerate four-wave mixing (DFWM) processes are investigated with a femtosecond pulsed laser in lithium niobate crystal doubly-doped with magnesium and iron (LiNbO3:Fe,Mg). The pulse energy dependence reveals a pure third-order nonlinear response, and the third-order nonlinear susceptibility χ(3) in the material is evaluated to be 4.96×10−13 esu. The time-resolved DFWM process shows a response time of χ(3) shorter than 100 fs, which is due to the nonresonant electronic nonlinearities. Our results indicate that LiNbO3 crystals have potentials for ultrafast real-time optical processing systems, which require a large and fast χ(3) optical nonlinearity.

Rapid increases in human populations provide a great challenge to ensure that adequate quantities of food are available. Sustainable development of agricultural production by breeding more productive cultivars and by increasing the productive potential of existing cultivars can help meet this demand. The present paper provides information on the potential uses of cryogenic techniques in ensuring food security, including: (1) long-term conservation of a diverse germplasm and successful establishment of cryo-banks; (2) maintenance of the regenerative ability of embryogenic tissues that are frequently the target for genetic transformation; (3) enhancement of genetic transformation and plant regeneration of transformed cells, and safe, long-term conservation for transgenic materials; (4) production and maintenance of viable protoplasts for transformation and somatic hybridization; and (5) efficient production of pathogen-free plants. These roles demonstrate that cryogenic technologies offer opportunities to ensure food security. © 2014 Elsevier Inc.

This article sets out from the angle of systemic risk assessment, identification and control. Based on the deep research on coupling warning technology of multi-source information in weighty disasters, combined index system of weighty gas disasters in coal mines has been established, and the method of abnormal risk positioning of time and space combined with control chart and histogram has been put forward. Based on the coal mine safety risk, the article establishes risk management models of technology guarantee mechanism, organization guarantee mechanism, education training mechanism, safety culture mechanism. Comprehensive warning system of multi-source have been developed about great coal mine gas disasters, and the system integrates 6 kinds of security risk analysis and assessment methods as well as 5 kinds of prediction methods in regional or working face coal and gas outburst risk. Industrial application shows that the risk assessment system can improve the systematization and accuracy of weighty gas disasters in coal mine, and has an important significance in gas disasters prevention and control.

Objective To evaluate the impact of testicular sperm aspiration on the clinical outcomes of IVF patients with temporary ejaculation failure (TEF) on the day of oocyte retrieval. Design A case-control study. Setting University-affiliated IVF center. Patient(s) One hundred eight infertile couples encountering TEF on the day of oocyte retrieval. Intervention(s) Testicular sperm aspiration and intracytoplasmic sperm injection (TESA-ICSI) were employed to help the TEF couples to complete their IVF treatments. A group of obstructive azoospermia (OA) patients was chosen as a control group to evaluate the efficiency and safety of this intervention. Main Outcome Measure(s) Fertilization rates, transferable embryo rates, and clinical pregnancy rates (PRs). Result(s) Through the TESA-ICSI, TEF couples achieved a 38.83% (40/103) clinical PR per IVF cycle. Compared with the OA group, the TEF group showed a comparable fertilization rate (66.43% vs. 65.25%), transferable embryo rate (60.76% vs. 60.85%), and PR (51.61% vs. 50.00%) in thawed ET cycles but a relatively low PR (25.49% vs. 44.64%) in fresh ET cycles. Conclusion(s) TESA-ICSI is a relatively efficient and safe way to help the patients encountering TEF.

Direct-current transfer characteristics of (InGaN)/AlGaN/AlN/GaN heterojunction field effect transistors (HFETs) are presented. A drain current plateau (IDS = 32.0 mA/mm) for VGS swept from +0.7 V to −0.6 V is present in the transfer characteristics of InGaN/AlGaN/AlN/GaN HFETs. The theoretical calculation shows the coexistence of two-dimensional electron gas (2DEG) and two-dimensional hole gas (2DHG) in InGaN/AlGaN/AlN/GaN heterostructures, and the screening effect of 2DHG to the 2DEG in the conduction channel can explain this current plateau. Moreover, the current plateau shows the time-dependent behavior when IDS−VGS scans repeated are conducted. The obtained insight provides indication for the design in the fabrication of GaN-based super HFETs.

Highly efficient organic light-emitting diode is fabricated with a novel double hole injection layer consisting of MeO-TPD/CuPc. We observe that the insertion of such a double hole injection layer leads to a striking enhancement in the electrical property:higher luminance, power efficiency and lower driving voltage. It has the configuration of ITO/MeO-TPD (15 nm)/CuPc(15 nm)/NPB(15 nm)/Alq3 (50 nm)/LiF(1 nm)/Al(120 nm). Its turn-on voltage is 3.2 V, which is 2, 0.3 and 0.1 V lower than those of the device without hole injection layer (device A) and the devices using MeO-TPD (device B), CuPc (device C) as hole injection layer, respctively. The highest luminance of the novel device reaches 23893 cd/m2 at a drving voltage of 10 V. The maximum power efficiency of the novel decive is 1.91 lm/W, which is 43% (1.34 lm/W), 22% (1.57 lm/W) and 7% (1.79 lm/W) higher than those of devices A, B and C, respectively. The improvement is ascribed to its high hole injection and transport ability. The results are verified by using the J-V curves of "hole-only" devices.

The purpose of the paper is to solve gas limitation of the upper corner of working face of the protective seam. According to the actual situation of the 12nd Mine of the Ping Dingshan Mining Group Corporation (hereinafter referred to 12nd Mine), the technology of progressive and large diameter buried drainage pipe by crossing-hole was put forward, by the way of numerical simulation and field tests. The best reasonable distance and drainage hole diameter of the buried drainage pipe was obtained through the FLUENT simulation, and in accordance with the actual site, the protective seam Ji 14-31010 and Ji 15-31010 have implemented the buried drainage pipe in the site layout, and effective analysis was carried out. It's known by the actual performance that the technology can solve the problem of the gas limitation in the upper corner effectively.

The new perspective in visual classification aims to decode the feature representation of visual objects from human brain activities. Recording electroencephalogram (EEG) from the brain cortex has been seen as a prevalent approach to understand the cognition process of an image classification task. In this study, we proposed a deep learning framework guided by the visual evoked potentials, called the Event-Related Potential (ERP)-Long short-term memory (LSTM) framework, extracted by EEG signals for visual classification. In specific, we first extracted the ERP sequences from multiple EEG channels to response image stimuli-related information. Then, we trained an LSTM network to learn the feature representation space of visual objects for classification. In the experiment, 10 subjects were recorded by over 50,000 EEG trials from an image dataset with 6 categories, including a total of 72 exemplars. Our results showed that our proposed ERP-LSTM framework could achieve classification accuracies of cross-subject of 66.81% and 27.08% for categories (6 classes) and exemplars (72 classes), respectively. Our results outperformed that of using the existing visual classification frameworks, by improving classification accuracies in the range of 12.62% - 53.99%. Our findings suggested that decoding visual evoked potentials from EEG signals is an effective strategy to learn discriminative brain representations for visual classification., Comment: This paper is submitting to ICONIP 2020