1. Metastatic choriocarcinoma with hemorrhagic complications and spontaneous ovarian hyperstimulation syndrome: A case report
- Author
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Valerio D'Agostino, Antonio Catelli, Davide Raffaele De Lucia, Leonardo Radice, Raffaele Ascione, Ilaria Pesce, Luigi Coppola, and Anna Castaldo
- Subjects
medicine.medical_specialty ,endocrine system ,medicine.drug_class ,Trophoblastic Tumor ,Uterus ,R895-920 ,Ovarian hyperstimulation syndrome ,Case Report ,Choriocarcinoma syndrome ,Gastroenterology ,MRI, Magnetic Resonance Imaging ,Gestational choriocarcinoma ,FSH, Follicle Stimulating Hormone ,Medical physics. Medical radiology. Nuclear medicine ,Vascularity ,Internal medicine ,medicine ,b-hCG, Beta Human Chorionic Gonadotropin ,OHSS, Ovarian Hyperstimulation Syndrome ,Radiology, Nuclear Medicine and imaging ,CE-CT, Contrast Enhancement Computed Tomography ,LH, Luteinizing Hormone ,MIP, Maximum Intensity Projection ,TSH, Thyroid Stimulating Hormone ,Hypervascular metastases ,business.industry ,Choriocarcinoma ,US, Ultrasonography ,Hemorrhagic metastases ,HU, Hounsfield Unit ,medicine.disease ,Primary tumor ,female genital diseases and pregnancy complications ,medicine.anatomical_structure ,embryonic structures ,MPR, Multiplanar Reconstruction ,Gonadotropin ,medicine.symptom ,business - Abstract
Gestational choriocarcinoma is a malignant trophoblastic tumor arising from any gestational event, even with a long latency period, generally in the reproductive female. It is associated with a high level of beta-human chorionic gonadotropin. Its primary site is usually the uterus but not all patients have a detectable lesion in this site. Regression of the primary tumor after it has metastasized is not uncommon, and one-third of cases manifest as complications of metastatic disease. In this report we present an uncommon case of gestational choriocarcinoma with lung, liver and jejunal metastases at the time of diagnosis without evidence of pelvic disease, in 34-year-old woman. The main points of interest of our case were the development of the ovarian hyperstimulation syndrome with massive multicystic ovarian enlargement induced by high level of beta-human chorionic gonadotropin and the bleeding of jejunal and liver metastases, due to the high vascularity of the tumor tissue, a condition known as “Choriocarcinoma Syndrome”. We will focus on the radiological findings of metastases, bleeding complications and ovarian hyperstimulation syndrome.
- Published
- 2021