1. Improvement of Coronary Calcium Scores After Bariatric Surgery in People with Severe Obesity
- Author
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Amr Mahmoud Hussein, Abd Al-Kareem Elias, Amir Mostafa, Hossam El-Din Shaaban, Marwan Mansour Borham, Mohamed Abd Al-Fattah, Mohamed Shehata, Mohamed Hassan Elkaseer, Nader M. Milad, Ahmad Samir, Hazem Abd Allah Ali, Ahmed Abd El Aal Sultan, Mohamed Tourky, Mohamed Abdalla Salman, Mohamed Matter, Hani Maurice Sabri Mikhail, Hany A Balamoun, Nabil Ibrahim Fayad, Ahmed Abdallah Salman, and Haitham S. E. Omar
- Subjects
Blood Glucose ,medicine.medical_specialty ,Endocrinology, Diabetes and Metabolism ,Bariatric Surgery ,Gastrectomy ,Weight loss ,Diabetes mellitus ,Weight Loss ,Humans ,Medicine ,Prospective Studies ,Risk factor ,Prospective cohort study ,Nutrition and Dietetics ,Framingham Risk Score ,medicine.diagnostic_test ,business.industry ,medicine.disease ,Obesity ,Obesity, Morbid ,Coronary Calcium Score ,Surgery ,Treatment Outcome ,Calcium ,Laparoscopy ,medicine.symptom ,business ,Lipid profile - Abstract
Obesity is an independent risk factor for cardiovascular diseases. Coronary artery calcium (CAC) is a direct measure of coronary atherosclerosis. The study investigated the effect of bariatric surgery on CAC scores in people with severe obesity subjected to laparoscopic sleeve gastrectomy (LSG). This prospective study included 129 people with severe obesity in two groups; the LSG group (n=74) subjected to surgery and the diet group (n=55), managed by a diet regimen and lifestyle modification. Cardiovascular risk was assessed by Framingham risk score (FRS) and coronary calcium score (CCS) measured by computed tomography initially and after 3 years. The two groups had a comparable CAD risk before treatment according to FRS or CCS. After treatment, CCS improved significantly in the LSG group (p=0.008) but not in the diet group (p=0.149). There was no correlation between FRS and CCS (r=0.005, p=0.952). Treatment resulted in significant weight reduction and improved fasting blood glucose and lipid profile in the two groups. The change of weight, blood glucose, and HDL, and remission of diabetes mellitus (DM) were significantly higher in the LSG group compared to the diet group. LSG may reduce the risk of developing future cardiovascular comorbidities evidenced by reducing CAC scores. Significant weight reduction and improvement of cardiovascular risk factors may recommend LSG as a cardioprotective procedure in people with severe obesity.
- Published
- 2021
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