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Background Enterobacteria and multidrug-resistant non-fermenting Gram-negative bacilli present a challenge in the management of invasive infections, leading to mortality rates due to their limited therapeutic arsenal. The objective of this work was to analyze risk factors that may be associated with these infections, for a better situational mapping and assertive decision-making in a university hospital in Brazil. Methods The study was conducted between January and September 2019, with 167 patients in contact isolation at a university hospital in Brazil. Potential outcome-related variables for wide-resistance Gram-negative bacteria (BGN) infections were evaluated. Risk factors were identified from univariate statistical analysis using Fisher’s test. Results 51 (30.5%) out of 167 patients in contact isolation evolved with wide-resistance BGN infection. Risk factors in univariate analysis were age, hospital unit and previous use of invasive devices. Patients aged up to 59 years were more likely to progress to infection than those aged over 60 years (p 0.0274, OR 2.2, 95% CI 1.1-4.5). Those admitted to the oncohematology (p < 0.001, OR 32.5, Cl 9.1-116.3) and intensive care unit (p < 0.001, OR 28.0, Cl 3.5-225.9) units were more likely to develop this type of infection. The least likely were those admitted to a kidney transplant unit (p 0.0034, OR 15.33, Cl 1.8-131.0). Prior use of mechanical ventilation (p 0.0058, OR 12.2, Cl 2.0-76.1) and delayed bladder catheter (p 0.0266, OR 5.0, Cl 1.2-20.1) in patients with respiratory and urinary tract infection, respectively, were also reported as risk factors related to these infections. The gender of the patients was not significant for the study. Conclusion This study determined that variables such as age, hospitalization unit, use of mechanical ventilation and delayed bladder catheter could be considered important risk factors in triggering the infectious process by wide-resistant gram-negative bacteria. Thus, the analysis of these factors becomes a great foundation to prevent the development of multiresistant pathogens through prevention strategies, prophylaxis management and more targeted empirical therapies. Disclosures All Authors: No reported disclosures

Objective To evaluate the self-eye examination practice as a tool to promote the ocular self-evaluation. Method Quasi-experimental study developed in a university of Piauí with sample of 324 students between January and May 2014. A team of thirteen researchers made observations during the self-examination followed by an ocular screening. Results There was no agreement on the hypothesis of defense that the ocular exam could help to observe the eyes health, p-value>0.3. However, the exam was considered as easy to accomplish (99.7%) and that not only the physician can perform the eye exam (99.4%). The awareness about eye care is identified as the main purpose of this booklet (97.6%), (χ2= 186.01; p=0.001). The results highlight the booklet can be used in the teaching process of self-eye examination (84.6%). Although the defense that its fulfilment can replace the consultation with the ophthalmologist (23.8%%) cannot be accepted (χ2= 46.34), the self-exam must be done routinely (82.4%). Conclusion The results prove that the learning through virtual booklet is possible and supports self-care with the eyes by performing the self-exam. RESUMO Objetivo Avaliar a prática do autoexame como uma ferramenta para promover a autoavaliação ocular. Método Estudo quase-experimental, desenvolvido em uma universidade do Piauí, com uma amostra de 324 estudantes, entre janeiro e maio de 2014, por uma equipe de 13 pesquisadores, os quais fizeram observações durante o autoexame seguido de uma triagem ocular. Resultados Não houve concordância sobre a hipótese de que o exame ocular poderia ajudar a observar a saúde do olho (p-valor> 0,3), no entanto, foi considerado de fácil realização (99,7%), e que não só o médico pode realizá-lo (99,4%). A conscientização do cuidado com os olhos é identificada como o principal objetivo do uso da cartilha (97,6%), (χ2 = 186,01; p = 0,001). O resultado destaca que o material educativo pode ser utilizado no processo de ensino do autoexame ocular (84,6%). Embora a realização do autoexame não possa substituir a consulta com o oftalmologista (23,8%), (χ2 = 46,34), ele deve ser feito rotineiramente (82,4%). Conclusão Os resultados comprovam que o aprendizado por meio de uma cartilha virtual é possível, apoiando o autocuidado com os olhos através da realização do autoexame. RESUMEN Objetivo Evaluar la práctica del autoexamen como herramienta para promocionar la autoevaluación ocular. Método Estudio cuasi-experimental, desarrollado en una universidad de Piauí, con una muestra de 324 estudiantes, entre enero y mayo de 2014, por un equipo de trece investigadores, quienes hicieron observaciones durante el autoexamen seguido de un cribado ocular. Resultados No hubo concordancia acerca del supuesto de que el examen ocular podría ayudar a observar la salud ocular (valor-p >; 0,3). Sin embargo, se consideró como de fácil realización (99,7%) y que no solo el médico puede llevar a cabo el examen ocular (99,4%). Se identifica la concienciación acerca del cuidado ocular como la razón principal para el empleo de la cartilla (97,6%), (χ2 = 186,01; p =0,001). El resultado subraya que el método educativo se puede utilizar en el proceso de enseñanza del autoexamen ocular (84,6%). Aunque la realización del autoexamen no pueda reemplazar la consulta con el oftalmólogo (23,8%), (χ2= 46,34), se debe hacerlo de rutina (82,4%). Conclusión Los resultados comprueban que el aprendizaje mediante una cartilla virtual es posible, sosteniendo el autocuidado con los ojos mediante la realización del autoexamen.