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3 results on '"Świerk, P."'

1. Systematic literature reviews over the years

Author

Beata Smela, Mondher Toumi, Karolina Świerk, Konrad Gawlik, Emilie Clay, and Laurent Boyer

Subjects
Systematic literature review, randomized controlled trial, ICD-10 classification, rapid review, Public aspects of medicine, RA1-1270, Business, HF5001-6182
Abstract

ABSTRACTPurpose: Nowadays, systematic literature reviews (SLRs) and meta-analyses are often placed at the top of the study hierarchy of evidence. The main objective of this paper is to evaluate the trends in SLRs of randomized controlled trials (RCTs) throughout the years.Methods: Medline database was searched, using a highly focused search strategy. Each paper was coded according to a specific ICD-10 code; the number of RCTs included in each evaluated SLR was also retrieved. All SLRs analyzing RCTs were included. Protocols, commentaries, or errata were excluded. No restrictions were applied.Results: A total of 7,465 titles and abstracts were analyzed, from which 6,892 were included for further analyses. There was a gradual increase in the number of annual published SLRs, with a significant increase in published articles during the last several years. Overall, the most frequently analyzed areas were diseases of the circulatory system (n = 750) and endocrine, nutritional, and metabolic diseases (n = 734). The majority of SLRs included between 11 and 50 RCTs each.Conclusions: The recognition of SLRs’ usefulness is growing at an increasing speed, which is reflected by the growing number of published studies. The most frequently evaluated diseases are in alignment with leading causes of death and disability worldwide.

Published
2023
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2. Rapid literature review: definition and methodology

Author

Beata Smela, Mondher Toumi, Karolina Świerk, Clement Francois, Małgorzata Biernikiewicz, Emilie Clay, and Laurent Boyer

Subjects
Rapid review, systematic literature review, methodology, Delphi consensus, Public aspects of medicine, RA1-1270, Business, HF5001-6182
Abstract

ABSTRACTIntroduction: A rapid literature review (RLR) is an alternative to systematic literature review (SLR) that can speed up the analysis of newly published data. The objective was to identify and summarize available information regarding different approaches to defining RLR and the methodology applied to the conduct of such reviews.Methods: The Medline and EMBASE databases, as well as the grey literature, were searched using the set of keywords and their combination related to the targeted and rapid review, as well as design, approach, and methodology. Of the 3,898 records retrieved, 12 articles were included.Results: Specific definition of RLRs has only been developed in 2021. In terms of methodology, the RLR should be completed within shorter timeframes using simplified procedures in comparison to SLRs, while maintaining a similar level of transparency and minimizing bias. Inherent components of the RLR process should be a clear research question, search protocol, simplified process of study selection, data extraction, and quality assurance.Conclusions: There is a lack of consensus on the formal definition of the RLR and the best approaches to perform it. The evidence-based supporting methods are evolving, and more work is needed to define the most robust approaches.

Published
2023
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3. Monte Carlo studies for the optimisation of the Cherenkov Telescope Array layout

Author

Katsuaki Asano, Rodrigo Guedes Lang, M. Cieślar, Nicholas F. H Tothill, Gianpiero Tagliaferri, O. Le Blanc, M. Vazquez Acosta, Nicola Giglietto, S. Mangano, Julien Lefaucheur, Tatsuo Yoshida, D. de Martino, Martin Pohl, A. Shalchi, Y. Renier, B. Biasuzzi, T. B. Humensky, E. Fiandrini, Andreas Quirrenbach, Abelardo Moralejo, Carla Aramo, Vincenzo Rizi, J. Knapp, A. Pagliaro, Andrea Santangelo, Michael Punch, Andreas Specovius, A. M. Lopez, P. Peñil Del Campo, Henry Przybilski, J.-P. Lenain, Agnieszka Slowikowska, Satoshi Fukami, M. H. Grondin, S. Schlenstedt, Marek Nikolajuk, F. Schüssler, Maria Concetta Maccarone, Michael Zacharias, Francesco Giordano, T. Suomijärvi, Lorenzo Amati, J. Becker Tjus, Maxim V. Barkov, H. Prokoph, F.G. Saturni, R. J. White, Nu. Komin, María Isabel Bernardos, M. Orienti, Denis Bastieri, Justin Vandenbroucke, P. Vallania, Diego Falceta-Gonçalves, L. Tibaldo, A. Burtovoi, A. Viana, Takanori Yoshikoshi, Roberto Aloisio, Soebur Razzaque, M. Valentino, P. Da Vela, Pol Bordas, Francesco Longo, N. Otte, V. La Parola, E. O. Angüner, Marco Berton, Elina Lindfors, Salvo Scuderi, Hiroyasu Tajima, M. Prouza, E. Mach, P. Goldoni, C. Alispach, M. I. Martínez, Miroslav Pech, Kai Brügge, G. Vasileiadis, A. Nagai, A. Brill, Dusan Mandat, Geoff Romeo, M. Marculewicz, Cameron B Rulten, Fuyuki Tokanai, Luis Ángel Tejedor, Thomas Lohse, Anderson Caproni, Karol Seweryn, G. Bonnoli, D. Ninci, G. Pareschi, Stefan Kimeswenger, I. Sadeh, Łukasz Stawarz, M. Nöthe, Daniel Mazin, Ruben Alfaro, G. Busetto, Massimo Persic, A. Berti, G. Sironi, Pavel Horvath, Włodek Kluźniak, Pietro Bruno, Petr Travnicek, Daniel Kerszberg, M. Hayashida, Tomasz Szepieniec, A. Rugliancich, Marina Manganaro, Y. Ohtani, Samuel Timothy Spencer, L. Di Venere, S. Karkar, M. Füßling, E. de Oña Wilhelmi, Louis Antonelli, M. Lemoine-Goumard, Benjamin Koch, P.-O. Petrucci, M. de Naurois, Felix Werner, S. Sakurai, J. J. Rodríguez Vázquez, Petr Janecek, L. Dangeon, G. Fontaine, Alison Mitchell, Maria Magdalena González, Francesco Dazzi, Philip Kaaret, Reinaldo Santos-Lima, F. Di Pierro, Tomislav Terzić, Grzegorz Kowal, Stefan Wagner, R. A. Cameron, G. S. Varner, M. Roncadelli, Wystan Benbow, C. Bonavolontà, David Kieda, M. A. Leigui de Oliveira, Ullrich Schwanke, Y. Iwamura, K. Sedlaczek, R. C. Shellard, Q. Feng, David A. Williams, A. De Angelis, T. Nagayoshi, P. Sangiorgi, I. A. Minaya, Etienne Lyard, Juan Abel Barrio, B. De Lotto, S. Nozaki, J. Gironnet, L. Mohrmann, Oscar Blanch, Marcello Giroletti, Jean-Luc Meunier, Valentina Fioretti, S. Masuda, V. Vagelli, Rodolfo Canestrari, L. Freixas Coromina, M. Palatka, T. Di Girolamo, Vincenzo Testa, Tsuguya Naito, J. Becerra González, R. Alves Batista, Samo Stanič, S. D. Vergani, Lorenzo Bellizzi, Catherine Boisson, Olivier Hervet, P. Cumani, Konstancja Satalecka, Stefan Funk, Michele Doro, Pedro L. Luque-Escamilla, P. Romano, E. Fedorova, Carlo Vigorito, M. Zavrtanik, Markus Gaug, Stanislav Stefanik, R. J. García López, F. de Palma, V. Beshley, T.R.N. Ekoume, Enrico Congiu, Pierre Brun, Manuela Mallamaci, Barbara Balmaverde, L. Valore, Gino Tosti, Enrico Cascone, Marek Jamrozy, V. I. Zhdanov, Gavin Rowell, Elisabetta Bissaldi, M. Fiori, M. Capalbi, J. Bregeon, Dario Hrupec, F. Toussenel, R. Paoletti, Fulvio Gianotti, Ayan Acharyya, G. Spengler, P. Majumdar, A.A. Zdziarski, A. López-Oramas, M. Mariotti, Juri Poutanen, G. Ferrand, Paweł Świerk, M. Garczarczyk, S. Rainò, Tsunefumi Mizuno, Diego F. Torres, Ciro Bigongiari, Matteo Cerruti, M. Polo, Csaba Balázs, A. Dmytriiev, T. Gasparetto, D. Dorner, A. W. Chen, Elisa Prandini, Vitalii Sliusar, Helene Sol, Rodolfo Carosi, Jonathan Biteau, Vito Conforti, G. Rodriguez Fernandez, Shanta M. Zimmer, J. M. Paredes, S. Vercellone, Jonathan Granot, Alice Donini, Antonio Stamerra, Jaime Rosado, Michael G. Burton, Bohdan Hnatyk, F. D'Ammando, D. Nosek, M. Heller, Gagik Tovmassian, N. Produit, Petr Schovanek, German Martinez, G. Pühlhofer, S. Fegan, A. Kong, G. Morlino, G. Emery, H.-S. Zechlin, Tomasz Bulik, Antonino D'Ai, Riccardo Rando, Rocco Lico, K. Pfrang, D. Hadasch, R. López-Coto, A. Vollhardt, Pankaj Kushwaha, Petar Temnikov, Emmanuel Moulin, Luca Zampieri, Michiko Ohishi, C. Maggio, V. de Souza, Q. Piel, Marc Ribó, Werner Hofmann, A. Wierzcholska, Luisa Arrabito, Gianpaolo Vettolani, J. Pérez-Romero, Paramita Barai, Sylvain Chaty, N. Parmiggiani, V. Vassiliev, K. Nishijima, D. Cauz, S. Caroff, Giuseppe Leto, J.F. Glicenstein, Maria Ionica, Eva Sciacca, A. Bonardi, Juan Carlos Rodríguez-Ramírez, Marcos Santander, H. Siejkowski, Daniela Maria Ribeiro, Ralph Bird, S. Mićanović, D. Zavrtanik, Carole Mundell, Jan Ebr, Koji Noda, Elisa Bernardini, R. Gnatyk, Pierre Jean, M. Nievas Rosillo, M. López, Olga Sergijenko, R. Walter, Oleh Petruk, M. Del Santo, D. Elsasser, Jakub Juryšek, H. Martínez-Huerta, Andreas Zech, Jose J. Gonzalez, Akira Okumura, M. Iori, A. Ghalumyan, Jacco Vink, David Gascon, Jürgen Knödlseder, Daniel Nieto, R. A. Ong, Sabrina Casanova, B. Khélifi, S. Flis, G. Galanti, H. J. Voelk, Jim Hinton, M. Will, David H. Green, Giuseppe Malaguti, B. Rudak, A. Pe'Er, J. L. Dournaux, Andrea Bulgarelli, Frank M. Rieger, A. Djannati-Ataï, F. De Frondat, Lenka Tomankova, Moritz Hütten, Osvaldo Catalano, Hidetoshi Kubo, Tarek M. Hassan, Tomohiro Inada, Farinaldo S. Queiroz, J. Kushida, Daniel Morcuende, Jose Luis Contreras, F. Salesa Greus, Juan Cortina, Andreu Sanuy, S. Vorobiov, G. Maneva, B. Vallage, N. Maxted, N. Renault-Tinacci, P. Munar, M. Seglar-Arroyo, Fabrizio Tavecchio, Z. Ou, Anatolii Zenin, T. Tam, Miroslav Hrabovsky, G. Ambrosi, Giovanni Bonanno, R. Millul, Anastasia Maria Barbano, T. Grabarczyk, J. Zorn, D. Dominis Prester, R. D. Parsons, Luis H. S. Kadowaki, Elena Amato, M. Lallena Arquillo, I. Oya, Jacek Niemiec, Gianluca Giavitto, Marita Krause, Olaf Reimer, Josep Martí, M. Perri, Maria Chernyakova, Takeshi Nakamori, E. M. de Gouveia Dal Pino, Thomas Murach, P. Cristofari, C. Delgado, Fernando Catalani, G. La Rosa, J. Alfaro, Thomas Armstrong, J. Kocot, Léa Jouvin, Markus Böttcher, Rodrigo Nemmen, J. P. Amans, Utane Sawangwit, Y. Kobayashi, Hidetoshi Sano, D. Jankowsky, Heide Costantini, F. Arqueros, B. Bertucci, Sebastian Diebold, L. P. Taylor, Konstantinos N. Gourgouliatos, A. Fiasson, Miroslav Filipovic, R. Moderski, T. Stolarczyk, B. Patricelli, H. Ashkar, Alessandro Costa, Jonathan Blazek, C. Trichard, M. Vecchi, T. Greenshaw, A. Morselli, V. Vitale, A. M. Brown, S. M. Colak, Lili Yang, C. Díaz, J. Rico, P. Caraveo, S. Loporchio, Orel Gueta, Daniele Gaggero, V. De Caprio, R. Wischnewski, A. Sillanpää, C. J. Todero Peixoto, Takashi Saito, I. Agudo, Yasuo Fukui, Roberto Capuzzo-Dolcetta, F. Cassol, Manuel Meyer, Reiko Orito, G. Umana, M. V. Fonseca, U. Barres de Almeida, Saverio Lombardi, D. della Volpe, Giancarlo Cusumano, M. Ostrowski, T. Montaruli, L. Tosti, Garret Cotter, Konrad Bernlöhr, Reshmi Mukherjee, Fabio Iocco, M. Palatiello, Jonathan S. Lapington, U. Straumann, R. de Cássia dos Anjos, Matteo Balbo, Lab Saha, N. Hiroshima, G. Chiaro, D. Tonev, Ermanno Pietropaolo, Atreyee Sinha, Ministerio de Ciencia e Innovación (España), European Commission, Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Galaxies, Etoiles, Physique, Instrumentation (GEPI), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Univers et Particules de Montpellier (LUPM), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Astrophysique Interprétation Modélisation (AIM (UMR7158 / UMR_E_9005 / UM_112)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Institut de Physique Nucléaire d'Orsay (IPNO), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Univers et Théories (LUTH (UMR_8102)), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Leprince-Ringuet (LLR), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Centre d'Etudes Nucléaires de Bordeaux Gradignan (CENBG), Université Sciences et Technologies - Bordeaux 1 (UB)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de recherche en astrophysique et planétologie (IRAP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Institut de Planétologie et d'Astrophysique de Grenoble (IPAG), Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Observatoire des Sciences de l'Univers de Grenoble (OSUG ), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut national des sciences de l'Univers (INSU - CNRS)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Research unit Astroparticle Physics, Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Aix Marseille Université (AMU), PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Université de Montpellier (UM)-Université Montpellier 2 - Sciences et Techniques (UM2)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Astrophysique Interprétation Modélisation (AIM (UMR_7158 / UMR_E_9005 / UM_112)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Annecy de Physique des Particules (LAPP/Laboratoire d'Annecy-le-Vieux de Physique des Particules), Université Sciences et Technologies - Bordeaux 1-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Observatoire Midi-Pyrénées (OMP), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Centre National d'Études Spatiales [Toulouse] (CNES)-Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire des Sciences de l'Univers de Grenoble (OSUG), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Université Montpellier 2 - Sciences et Techniques (UM2)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Institut national des sciences de l'Univers (INSU - CNRS)-Université Toulouse III - Paul Sabatier (UT3), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS), Centre National d'Études Spatiales [Toulouse] (CNES)-Observatoire des Sciences de l'Univers de Grenoble (OSUG ), Institut national des sciences de l'Univers (INSU - CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Grenoble Alpes (UGA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Grenoble Alpes (UGA), Acharyya, A., Agudo, I., Anguner, E. O., Alfaro, R., Alfaro, J., Alispach, C., Aloisio, R., Alves Batista, R., Amans, J. -P., Amati, L., Amato, E., Ambrosi, G., Antonelli, L. A., Aramo, C., Armstrong, T., Arqueros, F., Arrabito, L., Asano, K., Ashkar, H., Balazs, C., Balbo, M., Balmaverde, B., Barai, P., Barbano, A., Barkov, M., Barres de Almeida, U., Barrio, J. A., Bastieri, D., Becerra Gonzalez, J., Becker Tjus, J., Bellizzi, L., Benbow, W., Bernardini, E., Bernardos, M. I., Bernlohr, K., Berti, A., Berton, M., Bertucci, B., Beshley, V., Biasuzzi, B., Bigongiari, C., Bird, R., Bissaldi, E., Biteau, J., Blanch, O., Blazek, J., Boisson, C., Bonanno, G., Bonardi, A., Bonavolonta, C., Bonnoli, G., Bordas, P., Bottcher, M., Bregeon, J., Brill, A., Brown, A. M., Brugge, K., Brun, P., Bruno, P., Bulgarelli, A., Bulik, T., Burton, M., Burtovoi, A., Busetto, G., Cameron, R., Canestrari, R., Capalbi, M., Caproni, A., Capuzzo-Dolcetta, R., Caraveo, P., Caroff, S., Carosi, R., Casanova, S., Cascone, E., Cassol, F., Catalani, F., Catalano, O., Cauz, D., Cerruti, M., Chaty, S., Chen, A., Chernyakova, M., Chiaro, G., Cieslar, M., Colak, S. M., Conforti, V., Congiu, E., Contreras, J. L., Cortina, J., Costa, A., Costantini, H., Cotter, G., Cristofari, P., Cumani, P., Cusumano, G., D'Ai, A., D'Ammando, F., Dangeon, L., Da Vela, P., Dazzi, F., De Angelis, A., De Caprio, V., de Cassia dos Anjos, R., De Frondat, F., de Gouveia Dal Pino, E. M., De Lotto, B., De Martino, D., de Naurois, M., de Ona Wilhelmi, E., de Palma, F., de Souza, V., Del Santo, M., Delgado, C., della Volpe, D., Di Girolamo, T., Di Pierro, F., Di Venere, L., Diaz, C., Diebold, S., Djannati-Atai, A., Dmytriiev, A., Dominis Prester, D., Donini, A., Dorner, D., Doro, M., Dournaux, J. -L., Ebr, J., Ekoume, T. R. N., Elsasser, D., Emery, G., Falceta-Goncalves, D., Fedorova, E., Fegan, S., Feng, Q., Ferrand, G., Fiandrini, E., Fiasson, A., Filipovic, M., Fioretti, V., Fiori, M., Flis, S., Fonseca, M. V., Fontaine, G., Freixas Coromina, L., Fukami, S., Fukui, Y., Funk, S., Fussling, M., Gaggero, D., Galanti, G., Garcia Lopez, R. J., Garczarczyk, M., Gascon, D., Gasparetto, T., Gaug, M., Ghalumyan, A., Gianotti, F., Giavitto, G., Giglietto, N., Giordano, F., Giroletti, M., Gironnet, J., Glicenstein, J. -F., Gnatyk, R., Goldoni, P., Gonzalez, J. M., Gonzalez, M. M., Gourgouliatos, K. N., Grabarczyk, T., Granot, J., Green, D., Greenshaw, T., Grondin, M. -H., Gueta, O., Hadasch, D., Hassan, T., Hayashida, M., Heller, M., Hervet, O., Hinton, J., Hiroshima, N., Hnatyk, B., Hofmann, W., Horvath, P., Hrabovsky, M., Hrupec, D., Humensky, T. B., Hutten, M., Inada, T., Iocco, F., Ionica, M., Iori, M., Iwamura, Y., Jamrozy, M., Janecek, P., Jankowsky, D., Jean, P., Jouvin, L., Jurysek, J., Kaaret, P., Kadowaki, L. H. S., Karkar, S., Kerszberg, D., Khelifi, B., Kieda, D., Kimeswenger, S., Kluzniak, W., Knapp, J., Knodlseder, J., Kobayashi, Y., Koch, B., Kocot, J., Komin, N., Kong, A., Kowal, G., Krause, M., Kubo, H., Kushida, J., Kushwaha, P., La Parola, V., La Rosa, G., Lallena Arquillo, M., Lang, R. G., Lapington, J., Le Blanc, O., Lefaucheur, J., Leigui de Oliveira, M. A., Lemoine-Goumard, M., Lenain, J. -P., Leto, G., Lico, R., Lindfors, E., Lohse, T., Lombardi, S., Longo, F., Lopez, A., Lopez, M., Lopez-Oramas, A., Lopez-Coto, R., Loporchio, S., Luque-Escamilla, P. L., Lyard, E., Maccarone, M. C., Mach, E., Maggio, C., Majumdar, P., Malaguti, G., Mallamaci, M., Mandat, D., Maneva, G., Manganaro, M., Mangano, S., Marculewicz, M., Mariotti, M., Marti, J., Martinez, M., Martinez, G., Martinez-Huerta, H., Masuda, S., Maxted, N., Mazin, D., Meunier, J. -L., Meyer, M., Micanovic, S., Millul, R., Minaya, I. A., Mitchell, A., Mizuno, T., Moderski, R., Mohrmann, L., Montaruli, T., Moralejo, A., Morcuende, D., Morlino, G., Morselli, A., Moulin, E., Mukherjee, R., Munar, P., Mundell, C., Murach, T., Nagai, A., Nagayoshi, T., Naito, T., Nakamori, T., Nemmen, R., Niemiec, J., Nieto, D., Nievas Rosillo, M., Nikolajuk, M., Ninci, D., Nishijima, K., Noda, K., Nosek, D., Nothe, M., Nozaki, S., Ohishi, M., Ohtani, Y., Okumura, A., Ong, R. A., Orienti, M., Orito, R., Ostrowski, M., Otte, N., Ou, Z., Oya, I., Pagliaro, A., Palatiello, M., Palatka, M., Paoletti, R., Paredes, J. M., Pareschi, G., Parmiggiani, N., Parsons, R. D., Patricelli, B., Pe'Er, A., Pech, M., Penil Del Campo, P., Perez-Romero, J., Perri, M., Persic, M., Petrucci, P. -O., Petruk, O., Pfrang, K., Piel, Q., Pietropaolo, E., Pohl, M., Polo, M., Poutanen, J., Prandini, E., Produit, N., Prokoph, H., Prouza, M., Przybilski, H., Puhlhofer, G., Punch, M., Queiroz, F., Quirrenbach, A., Raino, S., Rando, R., Razzaque, S., Reimer, O., Renault-Tinacci, N., Renier, Y., Ribeiro, D., Ribo, M., Rico, J., Rieger, F., Rizi, V., Rodriguez Fernandez, G., Rodriguez-Ramirez, J. C., Rodri-guez Vazquez, J. J., Romano, P., Romeo, G., Roncadelli, M., Rosado, J., Rowell, G., Rudak, B., Rugliancich, A., Rulten, C., Sadeh, I., Saha, L., Saito, T., Sakurai, S., Salesa Greus, F., Sangiorgi, P., Sano, H., Santander, M., Santangelo, A., Santos-Lima, R., Sanuy, A., Satalecka, K., Saturni, F. G., Sawangwit, U., Schlenstedt, S., Schovanek, P., Schussler, F., Schwanke, U., Sciacca, E., Scuderi, S., Sedlaczek, K., Seglar-Arroyo, M., Sergijenko, O., Seweryn, K., Shalchi, A., Shellard, R. C., Siejkowski, H., Sillanpaa, A., Sinha, A., Sironi, G., Sliusar, V., Slowikowska, A., Sol, H., Specovius, A., Spencer, S., Spengler, G., Stamerra, A., Stanic, S., Stawarz, L., Stefanik, S., Stolarczyk, T., Straumann, U., Suomijarvi, T., Swierk, P., Szepieniec, T., Tagliaferri, G., Tajima, H., Tam, T., Tavecchio, F., Taylor, L., Tejedor, L. A., Temnikov, P., Terzic, T., Testa, V., Tibaldo, L., Todero Peixoto, C. J., Tokanai, F., Tomankova, L., Tonev, D., Torres, D. F., Tosti, G., Tosti, L., Tothill, N., Toussenel, F., Tovmassian, G., Travnicek, P., Trichard, C., Umana, G., Vagelli, V., Valentino, M., Vallage, B., Vallania, P., Valore, L., Vandenbroucke, J., Varner, G. S., Vasileiadis, G., Vassiliev, V., Vazquez Acosta, M., Vecchi, M., Vercellone, S., Vergani, S., Vettolani, G. P., Viana, A., Vigorito, C. F., Vink, J., Vitale, V., Voelk, H., Vollhardt, A., Vorobiov, S., Wagner, S. J., Walter, R., Werner, F., White, R., Wierzcholska, A., Will, M., Williams, D. A., Wischnewski, R., Yang, L., Yoshida, T., Yoshikoshi, T., Zacharias, M., Zampieri, L., Zavrtanik, M., Zavrtanik, D., Zdziarski, A. A., Zech, A., Zechlin, H., Zenin, A., Zhdanov, V. I., Zimmer, S., Zorn, J., Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Montpellier 2 - Sciences et Techniques (UM2), Durham University, Glorieta de la Astronomía s/n, Delegación Coyoacán, Pontificia Universidad Católica de Chile, Département de physique nucléaire et corpusculaire, Università degli Studi dell'Aquila and Gran Sasso Science Institute, Universidade de São Paulo (USP), PSL Research University, INAF - Osservatorio di astrofisica e scienza dello spazio di Bologna, INAF - Osservatorio Astrofisico di Arcetri, INFN Sezione di Perugia, Universitá degli Studi di Perugia, INAF - Osservatorio Astronomico di Roma, INFN Sezione di Napoli, University of Oxford, Universidad Complutense de Madrid, CNRS/IN2P3, University of Tokyo, Monash University, University of Geneva, INAF - Osservatorio Astronomico di Brera, Institute of Physical and Chemical Research, Centro Brasileiro de Pesquisas Físicas, INFN Sezione di Padova and Universitá degli Studi di Padova, Universidad de La Laguna, Ruhr-Universität Bochum, Harvard-Smithsonian Center for Astrophysics, Max-Planck-Institut für Kernphysik, INFN Sezione di Torino, Pidstryhach Institute for Applied Problems in Mechanics and Mathematics NASU, Université Paris-Saclay, University of California, INFN Sezione di Bari and Politecnico di Bari, The Barcelona Institute of Science and Technology, Institute of Physics of the Czech Academy of Sciences, INAF - Osservatorio Astrofisico di Catania, Radboud University Nijmegen, Dipartimento di Scienze Fisiche, IEEC-UB, North-West University, Columbia University, TU Dortmund University, University of Warsaw, Armagh Observatory and Planetarium, Stanford University, INAF - Istituto di Astrofisica Spaziale e Fisica Cosmica di Palermo, Núcleo de Astrofísica Teórica (NAT/UCS), INAF - Istituto di Astrofisica Spaziale e Fisica Cosmica di Milano, INFN Sezione di Pisa, Polish Academy of Sciences, INAF - Osservatorio Astronomico di Capodimonte, INFN Sezione di Trieste and Università degli Studi di Udine, University of the Witwatersrand, Dublin City University, CIEMAT, CPPM, INAF - Istituto di Radioastronomia, Cherenkov Telescope Array Observatory, Universidade Federal do Paraná (UFPR), Université Paris-Saclay), CSIC), Institut d'Estudis Espacials de Catalunya (IEEC), Institució Catalana de Recerca i Estudis Avançats (ICREA) Barcelona, INFN Sezione di Bari and Università degli Studi di Bari, Universität Tübingen, Obs de Paris, University of Rijeka, Universität Würzburg, LPNHE, Astronomical Observatory of Taras Shevchenko National University of Kyiv, Western Sydney University, INAF - Osservatorio Astronomico di Padova, Deutsches Elektronen-Synchrotron, Nagoya University, University of Amsterdam, Universidad Autónoma de Madrid, INFN Sezione di Trieste and Università degli Studi di Trieste, Universitat Autónoma de Barcelona, Yerevan Physics Institute, Universidad Andrés Bello UNAB, Academic Computer Centre CYFRONET AGH, The Open University of Israel, Max-Planck-Institut für Physik, Oliver Lodge Laboratory, UMR 5797, Konan University, KEK (High Energy Accelerator Research Organization), RCPTM, Josip Juraj Strossmayer University of Osijek, Universidade Estadual Paulista (Unesp), INFN Sezione di Roma, Jagiellonian University, Physikalisches Institut, Université Paul Sabatier, University of Iowa, Leopold-Franzens-Universität, Kyoto University, Tokai University, University of Leicester, Universidade Federal do ABC (UFABC), University of Turku, Humboldt University Berlin, Universidad de Jaén, Saha Institute of Nuclear Physics, Bulgarian Academy of Sciences, Faculty of Physics, University of New South Wales, Universität Zürich, Hiroshima University, INFN Sezione di Roma Tor Vergata, INAF - Istituto di Astrofisica e Planetologia Spaziali (IAPS), University of Bath, Saitama University, Yamanashi-Gakuin University, Yamagata University, Institute of Particle & Nuclear Physics, Tokushima University, Georgia Institute of Technology, Institut de Planétologie et d'Astrophysique de Grenoble, Univ. Savoie Mont Blanc, Universität Potsdam, Linnaeus University, Universität Heidelberg, University of Johannesburg, University of Adelaide, Tuscaloosa, National Astronomical Research Institute of Thailand, Dept of Physics and Astronomy, Nicolaus Copernicus University, University of Nova Gorica, University of Wisconsin, INAF - Osservatorio Astrofisico di Torino, University of Hawai'i at Manoa, Ibaraki University, KVI - Center for Advanced Radiation Technology, University of Utah, USA, GBR, FRA, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Angüner, E. O., Becerra González, J., Bernlöhr, K., Bonavolontá, C., Böttcher, M., Brügge, K., Cieślar, M., D’Aí, A., D’Ammando, F., de Cássia dos Anjos, R., de Oña Wilhelmi, E., Díaz, C., Djannati-Ataï, A., Elsässer, D., Füßling, M., Garcia López, R. J., González, J. M., González, M. M., Hütten, M., Khélifi, B., Kluźniak, W., Knödlseder, J., López, M., López-Coto, R., Martí, J., Martínez, M., Martínez, G., Martínez-Huerta, H., Nikołajuk, M., Nöthe, M., Pe’Er, A., Peñil Del Campo, P., Pérez-Romero, J., Pühlhofer, G., Rainò, S., Ribó, M., Rodrí-guez Vázquez, J. J., Sillanpää, A., Stanič, S., Stawarz, Ł., Świerk, P., Vázquez Acosta, M., GRAPPA (ITFA, IoP, FNWI), and High Energy Astrophys. & Astropart. Phys (API, FNWI)

Subjects
Cherenkov Telescope Array, Astronomy, Monte Carlo method, energy resolution, Monte Carlo simulations, Cherenkov telescopes, IACT technique, gamma rays, cosmic rays, 01 natural sciences, 7. Clean energy, law.invention, Observatory, law, site, Monte Carlo, 010303 astronomy & astrophysics, Physics, Astrophysics::Instrumentation and Methods for Astrophysics, observatory, Cosmic rays, Gamma rays, Astronomy and Astrophysics, ddc:540, Física nuclear, Monte carlo studies, Astrophysics::Earth and Planetary Astrophysics, Astrophysics - Instrumentation and Methods for Astrophysics, performance, FÍSICA DE ALTA ENERGIA, Astrophysics::High Energy Astrophysical Phenomena, Gamma ray, FOS: Physical sciences, energy dependence, Telescope, Optics, CTA - Abteilung Hofmann, 0103 physical sciences, Cherenkov counter: imaging, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Instrumentation and Methods for Astrophysics (astro-ph.IM), Monte Carlo simulation, Cherenkov radiation, CTA, 010308 nuclear & particles physics, business.industry, sensitivity, Cosmic ray, Cherenkov telescope, gamma ray: VHE, business, Energy (signal processing), astro-ph.IM
Abstract

The Cherenkov Telescope Array (CTA) is the major next-generation observatory for ground-based very-high-energy gamma-ray astronomy. It will improve the sensitivity of current ground-based instruments by a factor of five to twenty, depending on the energy, greatly improving both their angular and energy resolutions over four decades in energy (from 20 GeV to 300 TeV). This achievement will be possible by using tens of imaging Cherenkov telescopes of three successive sizes. They will be arranged into two arrays, one per hemisphere, located on the La Palma island (Spain) and in Paranal (Chile). We present here the optimised and final telescope arrays for both CTA sites, as well as their foreseen performance, resulting from the analysis of three different large-scale Monte Carlo productions.© 2019, We gratefully acknowledge financial support from the following agencies and organizations: State Committee of Science of Armenia, Armenia; The Australian Research Council, Astronomy Australia Ltd, The University of Adelaide, Australian National University, Monash University, The University of New South Wales, The University of Sydney, Western Sydney University, Australia; Federal Ministry of Science, Research and Economy, and Innsbruck University, Austria; Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq), Fundacao de Amparo a Pesquisa do Estado do Rio de Janeiro (FAPERJ), Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP), Ministry of Science, Technology, Innovations and Communications (MCTIC), Brasil; Ministry of Education and Science, National RI Roadmap Project D01-153/28.08.2018, Bulgaria; The Natural Sciences and Engineering Research Council of Canada and the Canadian Space Agency, Canada; CONICYT-Chile grants PFB-06, FB0821, ACT 1406, FONDECYT-Chile grants 3160153, 3150314, 1150411, 1161463, 1170171, Pontificia Universidad Catolica de Chile Vice-Rectory of Research internationalization grant under MINEDUC agreement PUC1566, Chile, Croatian Science Foundation, Rudjer Boskovic Institute, University of Osijek, University of Rijeka, University of Split, Faculty of Electrical Engineering, Mechanical Engineering and Naval Architecture, University of Zagreb, Faculty of Electrical Engineering and Computing, Croatia; Ministry of Education, Youth and Sports, MEYS LM2015046, LTT17006 and EU/MEYS CZ.02.1.01/0.0/0.0/16_013/0001403, CZ.02.1.01/0.0/0.0/17_049/0008422, Czech Republic; Ministry of Higher Education and Research, CNRS-INSU and CNRS-IN2P3, CEA-Irfu, ANR, Regional Council Ile-de France, Labex ENIGMASS, OSUG2020, P210 and OCEVU, France; Max Planck Society, BMBF, DESY, Helmholtz Association, Germany; Department of Atomic Energy, Department of Science and Technology, India; Istituto Nazionale di Astrofisica (INAF), Istituto Nazionale di Fisica Nucleare (INFN), MIUR, Istituto Nazionale di Astrofisica (INAF-OABRERA) Grant Fondazione Cariplo/Regione Lombardia ID 2014-1980/RST_ERC, Italy; ICRR, University of Tokyo, JSPS, MEXT, Japan; Netherlands Research School for Astronomy (NOVA), Netherlands Organization for Scientific Research (NWO), Netherlands; University of Oslo, Norway; Ministry of Science and Higher Education, DIR/WK/2017/12, the National Centre for Research and Development and the National Science Centre, UMO-2016/22/M/ST9/00583, Poland; Slovenian Research Agency, Slovenia, grants P1-0031, P1-0385, 10-0033, J1-9146; South African Department of Science and Technology and National Research Foundation through the South African Gamma-Ray Astronomy Programme, South Africa; MINECO National R+D+I, Severo Ochoa, Maria de Maeztu, CDTI, PAIDI, UJA, FPA2017-90566-REDC, Spain; Swedish Research Council, Royal Physiographic Society of Lund, Royal Swedish Academy of Sciences, The Swedish National Infrastructure for Computing (SNIC) at Lunarc (Lund), Sweden; Swiss National Science Foundation (SNSF), Ernest Boninchi Foundation, Switzerland; Durham University, Leverhulme Trust, Liverpool University, University of Leicester, University of Oxford, Royal Society, Science and Technology Facilities Council, UK; U.S. National Science Foundation, U.S.Department of Energy, Argonne National Laboratory, Barnard College, University of California, University of Chicago, Columbia University, Georgia Institute of Technology, Institute for Nuclear and Particle Astrophysics (INPAC-MRPI program), Iowa State University, the Smithsonian Institution, Washington University McDonnell Center for the Space Sciences, The University of Wisconsin and the Wisconsin Alumni Research Foundation, USA. The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreements no 262053 and no 317446. This project is receiving funding from the European Union's Horizon 2020 research and innovation programs under agreement no 676134.

Published
2019

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