1. Biochemical and Biological Profile of Parotoid Secretion of the Amazonian
- Author
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Daniel S S, de Medeiros, Tiago B, Rego, Ana P de A, Dos Santos, Adriana S, Pontes, Leandro S, Moreira-Dill, Najla B, Matos, Juliana P, Zuliani, Rodrigo G, Stábeli, Carolina B G, Teles, Andreimar M, Soares, Angelo R de M, Sperotto, Dinara J, Moura, Jenifer, Saffi, Cleópatra Alves da Silva, Caldeira, Daniel Carvalho, Pimenta, and Leonardo A, Calderon
- Subjects
Bufanolides ,Staphylococcus aureus ,Pseudomonas aeruginosa ,Animals ,Bufo marinus ,Parotid Gland ,Corrigendum ,Anti-Bacterial Agents ,Skin - Abstract
Skin secretions of frogs have a high chemical complexity. They have diverse types of biomolecules, such as proteins, peptides, biogenic amines, and alkaloids. These compounds protect amphibians' skin against growth of bacteria, fungi, and protozoa and participate in defense system against attack from predators. Therewith, this work performed biochemical and biological profile of macroglands parotoid secretion from cane toad. For poison analysis, we performed molecular exclusion and reverse phase chromatography, electrophoresis, and mass spectrometry. Antimicrobial, antiplasmodial, leishmanicidal, cytotoxicity, genotoxicity, and inflammatory activity of crude and/or fractions of
- Published
- 2018