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Your search keyword '"Levashova, A. I."' showing total 2 results
Start Over Author "Levashova, A. I." Topic brush polymers
2 results on '"Levashova, A. I."'

2. A DNA Biochip with Cells of Carboxylated Brush Polymers.

Author

Miftakhov, R. A., Ikonnikova, A. Yu., Vasiliskov, V. A., Lapa, S. A., Levashova, A. I., Kuznetsova, V. E., Shershov, V. E., Zasedatelev, A. S., Nasedkina, T. V., and Chudinov, A. V.

Subjects
NUCLEIC acid hybridization, DNA analysis, NUCLEIC acid probes, CARBOXYL group, DNA, CARBOXYLATES, ACRYLAMIDE
Abstract

A method for the photolithographic fabrication of biochips with hydrogel cells made of brush acrylic acid–acrylamide copolymers fixed by one end on the surface of a polymer substrate has been developed. Hydrogel cells with reactive carboxyl groups were used for covalent immobilization of oligonucleotide probes. The efficiency of the method was demonstrated by the hybridization analysis of DNA targets of different lengths, matching a segment of exon 7 of the human ABO gene. [ABSTRACT FROM AUTHOR]

Published
2023
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