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1. Lactate secreted via MCT4 from bone‑colonizing breast cancer excites sensory neurons via GPR81.

2. The lactate sensor GPR81 regulates glycolysis and tumor growth of breast cancer.

3. [Bone metastases of breast cancer].

4. Bone-derived IGF mediates crosstalk between bone and breast cancer cells in bony metastases.

5. [Involvement of RANKL/RANK pathway in bone metastasis in breast cancer].

6. Simvastatin prevents skeletal metastasis of breast cancer by an antagonistic interplay between p53 and CD44.

7. c-Src differentially regulates the functions of microtentacles and invadopodia.

8. Fish oil prevents breast cancer cell metastasis to bone.

9. Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: implication for breast cancer osteolytic bone metastases.

10. Cadherin-11-mediated interactions with bone marrow stromal/osteoblastic cells support selective colonization of breast cancer cells in bone.

11. Involvement of cell-cell and cell-matrix interactions in bone destruction induced by metastatic MDA-MB-231 human breast cancer cells in nude mice.

12. The neuronal guidance cue Slit2 induces targeted migration and may play a role in brain metastasis of breast cancer cells.

13. Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain.

14. Hypoxia and hypoxia-inducible factor-1 expression enhance osteolytic bone metastases of breast cancer.

15. Differential expression of matrix metalloproteinases in brain- and bone-seeking clones of metastatic MDA-MB-231 breast cancer cells.

16. In vivo MRI of cancer cell fate at the single-cell level in a mouse model of breast cancer metastasis to the brain.

17. Co-localization of cortactin and phosphotyrosine identifies active invadopodia in human breast cancer cells.

18. Stimulation of cyclooxygenase-2 expression by bone-derived transforming growth factor-beta enhances bone metastases in breast cancer.

19. Crosstalk between cancer cells and bone microenvironment in bone metastasis.

20. Zoledronic acid inhibits visceral metastases in the 4T1/luc mouse breast cancer model.

21. Bone sialoprotein promotes bone metastasis of a non-bone-seeking clone of human breast cancer cells.

22. Over-expression of bone sialoprotein enhances bone metastasis of human breast cancer cells in a mouse model.

23. C-SRC tyrosine kinase activity is associated with tumor colonization in bone and lung in an animal model of human breast cancer metastasis.

24. Hepatocyte growth factor enhances adhesion of breast cancer cells to endothelial cells in vitro through up-regulation of CD44.

25. Bone sialoprotein promotes tumor cell migration in both in vitro and in vivo models.

26. Phenotypic reversion or death of cancer cells by altering signaling pathways in three-dimensional contexts.

27. Tumor-derived platelet-derived growth factor-BB plays a critical role in osteosclerotic bone metastasis in an animal model of human breast cancer.

28. Regulation of breast cancer cell motility by insulin receptor substrate-2 (IRS-2) in metastatic variants of human breast cancer cell lines.

29. A bone-seeking clone exhibits different biological properties from the MDA-MB-231 parental human breast cancer cells and a brain-seeking clone in vivo and in vitro.

30. The bisphosphonate ibandronate promotes apoptosis in MDA-MB-231 human breast cancer cells in bone metastases.

31. Elevated levels of p66 Shc are found in breast cancer cell lines and primary tumors with high metastatic potential.

32. Cellular and molecular basis of preferential metastasis of breast cancer to bone.

33. Bisphosphonates as anticancer drugs.

34. Experimental bone metastasis model of the oral and maxillofacial region.

35. Cellular and molecular mechanisms of breast and prostate cancer metastasis to bone.

36. Arterial microvascularization and breast cancer colonization in bone.

37. Inhibition of osteolytic bone metastasis of breast cancer by combined treatment with the bisphosphonate ibandronate and tissue inhibitor of the matrix metalloproteinase-2.

38. E-cadherin expression in human breast cancer cells suppresses the development of osteolytic bone metastases in an experimental metastasis model.

39. Bisphosphonate risedronate reduces metastatic human breast cancer burden in bone in nude mice.

40. Osteolytic bone metastasis in breast cancer.

41. Inhibition of breast cancer cell growth in vitro by a tyrosine kinase inhibitor.

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