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Breast cancer is one of the most common cancers in women, with an estimated 287,850 new cases identified in 2022. There were 43,250 female deaths attributed to this malignancy. The high death rate associated with this type of cancer can be reduced with early detection. Nonetheless, a skilled professional is always necessary to manually diagnose this malignancy from mammography images. Many researchers have proposed several approaches based on artificial intelligence. However, they still face several obstacles, such as overlapping cancerous and noncancerous regions, extracting irrelevant features, and inadequate training models. In this paper, we developed a novel computationally automated biological mechanism for categorizing breast cancer. Using a new optimization approach based on the Advanced Al-Biruni Earth Radius (ABER) optimization algorithm, a boosting to the classification of breast cancer cases is realized. The stages of the proposed framework include data augmentation, feature extraction using AlexNet based on transfer learning, and optimized classification using a convolutional neural network (CNN). Using transfer learning and optimized CNN for classification improved the accuracy when the results are compared to recent approaches. Two publicly available datasets are utilized to evaluate the proposed framework, and the average classification accuracy is 97.95%. To ensure the statistical significance and difference between the proposed methodology, additional tests are conducted, such as analysis of variance (ANOVA) and Wilcoxon, in addition to evaluating various statistical analysis metrics. The results of these tests emphasized the effectiveness and statistical difference of the proposed methodology compared to current methods. [ABSTRACT FROM AUTHOR]

According to the American Cancer Society, breast cancer is the second largest cause of mortality among women after lung cancer. Women's death rates can be decreased if breast cancer is diagnosed and treated early. Due to the lengthy duration of manual breast cancer diagnosis, an automated approach is necessary for early cancer identification. This research proposes a novel framework integrating metaheuristic optimization with deep learning and feature selection for robustly classifying breast cancer from ultrasound images. The structure of the proposed methodology consists of five stages, namely, data augmentation to improve the learning of convolutional neural network (CNN) models, transfer learning using GoogleNet deep network for feature extraction, selection of the best set of features using a novel optimization algorithm based on a hybrid of dipper throated and particle swarm optimization algorithms, and classification of the selected features using CNN optimized using the proposed optimization algorithm. To prove the effectiveness of the proposed approach, a set of experiments were conducted on a breast cancer dataset, freely available on Kaggle, to evaluate the performance of the proposed feature selection method and the performance of the optimized CNN. In addition, statistical tests were established to study the stability and difference of the proposed approach compared to state-of-the-art approaches. The achieved results confirmed the superiority of the proposed approach with a classification accuracy of 98.1%, which is better than the other approaches considered in the conducted experiments. [ABSTRACT FROM AUTHOR]