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Your search keyword '"Decompressive Craniectomy standards"' showing total 3 results
Start Over Descriptor "Decompressive Craniectomy standards" Topic brain edema
3 results on '"Decompressive Craniectomy standards"'

1. Effect of decompressive craniectomy on aquaporin-4 expression after lateral fluid percussion injury in rats.

Author

Tomura S, Nawashiro H, Otani N, Uozumi Y, Toyooka T, Ohsumi A, and Shima K

Subjects
Animals, Brain Edema etiology, Brain Injuries complications, Disease Models, Animal, Homeostasis physiology, Intracranial Hypertension etiology, Male, Rats, Rats, Sprague-Dawley, Treatment Outcome, Aquaporin 4 biosynthesis, Brain Edema metabolism, Brain Edema surgery, Brain Injuries metabolism, Decompressive Craniectomy standards, Intracranial Hypertension metabolism, Intracranial Hypertension surgery
Abstract

Decompressive craniectomy is one therapeutic option for severe traumatic brain injury (TBI), and it has long been used for the treatment of patients with malignant post-traumatic brain edema. A lack of definitive evidence, however, prevents physicians from drawing any conclusions about the effects of decompressive craniectomy for the treatment of TBI. Therefore, the aim of the present study was to investigate the influence of decompressive craniectomy on post-traumatic brain edema formation. The aquaporin-4 (AQP4) water channel is predominantly expressed in astrocytes, and it plays an important role in the regulation of brain water homeostasis. In the present study, we investigated the time course of AQP4 expression and the water content of traumatized cortex following decompressive craniectomy after TBI. Adult male Sprague-Dawley rats (300-400 g) were subjected to lateral fluid percussion injury using the Dragonfly device. The effect of decompressive craniectomy was studied in traumatized rats without craniectomy (closed skull, DC-), and in rats craniectomized immediately after trauma (DC+). AQP4 expression was investigated with a Western blot analysis and immunohistochemistry. Brain edema was measured using the wet weight/dry weight method. At 48 h after TBI, AQP4 expression of the DC- group was significantly increased compared with the DC+ group (p < 0.01). In addition, the cortical water content of the DC- group was significantly increased compared to the DC+ group at the same time point (p < 0.05). The present results suggest that decompressive craniectomy may affect AQP4 expression and reduce brain edema formation after TBI.

Published
2011
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2. Surgical complications of decompressive craniectomy for head trauma.

Author

Kilincer C and Hamamcioglu MK

Subjects
Brain diagnostic imaging, Brain pathology, Brain physiopathology, Brain Edema etiology, Brain Edema physiopathology, Decompressive Craniectomy methods, Decompressive Craniectomy standards, Disease Progression, Emergency Medical Services, Functional Laterality physiology, Humans, Intracranial Hypertension etiology, Intracranial Hypertension physiopathology, Intracranial Hypertension prevention & control, Postoperative Complications etiology, Postoperative Complications physiopathology, Plastic Surgery Procedures methods, Plastic Surgery Procedures standards, Subdural Effusion etiology, Subdural Effusion physiopathology, Subdural Space diagnostic imaging, Subdural Space pathology, Subdural Space physiopathology, Tomography, X-Ray Computed, Treatment Outcome, Brain Edema prevention & control, Brain Injuries complications, Brain Injuries surgery, Decompressive Craniectomy adverse effects, Postoperative Complications prevention & control, Subdural Effusion prevention & control
Published
2010
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3. Subdural effusion secondary to decompressive craniectomy in patients with severe traumatic brain injury.

Author

Yang XF, Wen L, Gong JB, and Zhan RY

Subjects
Brain diagnostic imaging, Brain pathology, Brain physiopathology, Brain Edema etiology, Brain Edema physiopathology, Decompressive Craniectomy methods, Decompressive Craniectomy standards, Disease Progression, Emergency Medical Services, Functional Laterality physiology, Humans, Intracranial Hypertension etiology, Intracranial Hypertension physiopathology, Intracranial Hypertension prevention & control, Male, Postoperative Complications etiology, Postoperative Complications physiopathology, Plastic Surgery Procedures methods, Plastic Surgery Procedures standards, Subdural Effusion etiology, Subdural Effusion physiopathology, Subdural Space diagnostic imaging, Subdural Space pathology, Subdural Space physiopathology, Tomography, X-Ray Computed, Treatment Outcome, Brain Edema prevention & control, Brain Injuries complications, Brain Injuries surgery, Decompressive Craniectomy adverse effects, Postoperative Complications prevention & control, Subdural Effusion prevention & control
Published
2010
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