1. Retinopathy of prematurity, visual and neurodevelopmental outcome, and imaging of the central nervous system.
- Author
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Morken TS, Dammann O, Skranes J, and Austeng D
- Subjects
- Humans, Infant, Newborn, Infant, Premature, Neurodevelopmental Disorders diagnostic imaging, Prognosis, Vision Disorders diagnostic imaging, Brain diagnostic imaging, Magnetic Resonance Imaging, Neurodevelopmental Disorders etiology, Retinopathy of Prematurity diagnostic imaging, Retinopathy of Prematurity physiopathology, Tomography, Optical Coherence, Vision Disorders etiology
- Abstract
Recent findings indicate that retinopathy of prematurity (ROP), presently classified by clinical examinations of retinal vascular tissue, is associated with structural alterations of the central nervous system. Such alterations may be the correlate of the association between ROP and impaired long-term neurocognitive and visual development. The advent of imaging techniques such as structural and diffusion tensor magnetic resonance imaging of the brain, and optical coherence tomography of the retina, will allow the complete visual system to be characterized in greater detail. It has been suggested that ROP may be not only a vascular, but a neurovascular disease, being part of a spectrum that includes pathological development in both the retinal and cerebral neurovascular interphase. We review the present knowledge in the field and point to future directions for research to tackle these questions., (Copyright © 2019 Elsevier Inc. All rights reserved.)
- Published
- 2019
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