1. Varicella zoster virus cerebral aneurysmal vasculopathy presenting in a newly-diagnosed HIV-positive patient.
- Author
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Tomkins A, Babu C, Herwadkar A, Siripurapu R, and McKee D
- Subjects
- Adult, Anti-Retroviral Agents administration & dosage, Antiviral Agents administration & dosage, Computed Tomography Angiography, Encephalitis, Varicella Zoster drug therapy, Female, HIV Seropositivity drug therapy, Herpesvirus 3, Human isolation & purification, Humans, Intracranial Hemorrhages diagnostic imaging, Intracranial Hemorrhages virology, Magnetic Resonance Imaging, Prednisolone administration & dosage, Treatment Outcome, Varicella Zoster Virus Infection drug therapy, Brain blood supply, Brain diagnostic imaging, Cerebral Arterial Diseases diagnostic imaging, Encephalitis, Varicella Zoster complications, HIV Seropositivity diagnosis, Intracranial Aneurysm diagnostic imaging, Intracranial Hemorrhages etiology, Varicella Zoster Virus Infection diagnosis
- Abstract
We report the case of a newly-diagnosed HIV-positive patient with varicella zoster virus aneurysmal vasculopathy confirmed on intrathecal antibody testing, despite a negative Cerebrospinal fluid (CSF) Varicella Zoster Virus (VZV) Polymerase Chain Reaction (PCR). This highlights the importance of prompt treatment with antiviral and steroid therapy in the presence of clinical or radiological suspicion whilst awaiting further confirmatory testing.
- Published
- 2018
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