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Your search keyword '"Napolitani M."' showing total 2 results
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2 results on '"Napolitani M."'

1. Transcranial magnetic stimulation-evoked EEG/cortical potentials in physiological and pathological aging.

Author

Casarotto S, Määttä S, Herukka SK, Pigorini A, Napolitani M, Gosseries O, Niskanen E, Könönen M, Mervaala E, Rosanova M, Soininen H, and Massimini M

Subjects
Adult, Aged, Electroencephalography, Female, Humans, Male, Transcranial Magnetic Stimulation, Aging physiology, Alzheimer Disease physiopathology, Brain physiology, Brain physiopathology
Abstract

The frontal cortex undergoes macrostructural and microstructural changes across the lifespan. These changes can be entirely physiological, such as the ones occurring in elderly individuals who are cognitively intact, or pathological, such as the ones occurring in patients with Alzheimer's disease. Here, we use simultaneous electroencephalography (EEG) and transcranial magnetic stimulation (TMS) to study how the excitability of the frontal cortex changes during healthy and pathological aging. Hence, we compared the TMS-evoked EEG potentials collected in healthy elderly individuals with the ones collected in healthy young individuals, and in patients with Alzheimer's disease. We have shown that the EEG response to TMS of the left superior frontal cortex is not affected by physiological aging but is markedly altered by cognitive impairment.

Published
2011
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2. Multimodal neuroimaging in patients with disorders of consciousness showing 'functional hemispherectomy'

Author

Olivia Gosseries, Marie-Aurélie Bruno, Pierre Maquet, Rémy Lehembre, Luaba Tshibanda, Davinia Fernández-Espejo, Quentin Noirhomme, Michele Papa, Andrea Soddu, Audrey Vanhaudenhuyse, Steven Laureys, Adrian M. Owen, Martino Napolitani, Emilie Lommers, Mélanie Boly, Van Someren EJ, Bruno, Ma, FERNÁNDEZ ESPEJO, D, Lehembre, R, Tshibanda, L, Vanhaudenhuyse, A, Gosseries, O, Lommers, E, Napolitani, M, Noirhomme, Q, Boly, M, Papa, Michele, Owen, A, Maquet, P, Laureys, S, and Soddu, A.

Subjects
Diagnostic Imaging, Male, Adolescent, Hemispherectomy, Consciousne, medicine.medical_treatment, Neuroimaging, Electroencephalography, EEG-fMRI, Young Adult, Traumatic brain injury, Brain Injurie, medicine, EEG, Coma, Minimally conscious state, Persistent vegetative state, Vegetative state, Neuroscience (all), medicine.diagnostic_test, Resting state fMRI, Persistent Vegetative State, Brain, medicine.disease, Magnetic Resonance Imaging, Consciousness Disorder, PET, Diffusion Tensor Imaging, FMRI, Positron-Emission Tomography, Wakefulness, Neuropsychological Test, Psychology, Neuroscience, Human
Abstract

Beside behavioral assessment of patients with disorders of consciousness, neuroimaging modalities may offer objective paraclinical markers important for diagnosis and prognosis. They provide information on the structural location and extent of brain lesions (e.g., morphometric MRI and diffusion tensor imaging (DTI-MRI) assessing structural connectivity) but also their functional impact (e.g., metabolic FDG-PET, hemodynamic fMRI, and EEG measurements obtained in " resting state" conditions). We here illustrate the role of multimodal imaging in severe brain injury, presenting a patient in unresponsive wakefulness syndrome (UWS; i.e., vegetative state, VS) and in a " fluctuating" minimally conscious state (MCS). In both cases, resting state FDG-PET, fMRI, and EEG showed a functionally preserved right hemisphere, while DTI showed underlying differences in structural connectivity highlighting the complementarities of these neuroimaging methods in the study of disorders of consciousness. © 2011 Elsevier B.V.

Published
2011

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