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Aim: The function of the circle of Willis, an arterial polygon, is to protect the brain from ischemia. The aim of this study is to define the structural characteristics of the circle of Willis within the Turkish adult population, along with variations and arteries involved in the measurement of diameters and lengths on cadavers., Material and Methods: The circle of Willis was evaluated in 100 fresh adult cadavers. Structures of the circle of Willis were evaluated as being typical or atypical images and according to the diameter of AComP. All arteries forming the circle's length and diameters were measured., Results: All arteries forming the circle of Willis as 91% were anatomically observed. The typical structure in which hypoplasia arteries is not involved was obtained as 8%. The atypical circle of Willis with aplasia was seen as 9%. 87% of adult, 9% fetal, and 4% transitional configuration in the samples were detected. The variations of the circle of Willis were more common in the posterior portion. Hypoplasia was found to be the most common variation and noted as a maximum in AComP (85%). Aplasia was noted as the second most common variation after hypoplasia and again the most common in AComP (5%)., Conclusion: Advances in radiological methods which provide images of cerebral vessels and the development of cerebrovascular surgery have increased the importance of the circle of Willis in neurosurgery and neurology. The structure of the circle of Willis is of great importance in occlusive cerebrovascular diseases and cerebrovascular surgery.

BACKGROUND AND PURPOSE: Synthetic MRI enables the generation of various contrast-weighted images and quantitative data in a reasonable scanning time. We aimed to use synthetic MRI to assess the detection and underlying tissue characteristics of focal areas of signal intensity and normal-appearing brain parenchyma and morphometric alterations in the brains of patients with neurofibromatosis type 1. MATERIALS AND METHODS: Conventional MR imaging and synthetic MRI were prospectively obtained from 19 patients with neurofibromatosis type 1 and 18 healthy controls. Two neuroradiologists independently evaluated focal areas of signal intensity on both conventional MR imaging and synthetic MRI. Additionally, automatically segmented volume calculations of the brain in both groups and quantitative analysis of myelin, including the focal areas of signal intensity and normal-appearing brain parenchyma, of patients with neurofibromatosis type 1 were performed using synthetic MRI. RESULTS: The comparison of conventional MR imaging and synthetic MRI showed good correlation in the supratentorial region of the brain (κ = 0.82-1). Automatically segmented brain parenchymal volume, intracranial volume, and GM volumes were significantly increased in the patients with neurofibromatosis type 1 (P