1. Tumor histiocítico hemosiderótico de meninges, una lesión simuladora.
- Author
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Peralta Serna, Julieta Yasmín, De la Torre Rendón, Fernando Enrique, Ríos Nava, Roberto, and Salazar Castillo, Octavio A.
- Subjects
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RETICULUM cell sarcoma , *INTRACRANIAL tumors , *GRANULAR materials , *DENDRITIC cells , *BRAF genes ,CENTRAL nervous system tumors - Abstract
BACKGROUND: Histiocyte proliferations can have several clinical modalities and different meanings. They occur with "histiocytosis" in its most accepted and studied form. Malignant tumor forms belong to another group: histiocytic sarcoma or dendritic cell sarcomas, like leukemias with myelomonocytic differentiation, although they are also part of the differential diagnosis. CLINICAL CASE: A case of a 68-year-old woman with an extraaxial intracranial tumor lesion attached to the meninges is presented, in the intraoperative study was reported as melanoma. The definitive study was compatible with a benign lesion composed of histiocytes, confirmed by immunohistochemistry. A brown granular material stood out in the cytoplasm of most of the neoplastic cells, which was verified by Perls stain to be hemosiderin. CONCLUSIONS: We did not find a description of a similar case, apparently related to a chronic inflammatory process of the otomastoid and which we have finally interpreted as probably non-neoplastic. There are no reported histiocytic tumors of the central nervous system with these characteristics, therefore we propose an interpretation for this type of lesion: “Histiocytic hemosiderotic tumor of the meninges”. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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