1. Borrelia miyamotoi Serology in a Clinical Population With Persistent Symptoms and Suspected Tick-Borne Illness
- Author
-
Shannon L. Delaney, Lilly A. Murray, Claire E. Aasen, Clair E. Bennett, Ellen Brown, and Brian A. Fallon
- Subjects
Borrelia miyamotoi disease ,relapsing fever borrelia ,Lyme disease ,serodiagnosis ,post-treatment Lyme disease syndrome ,borreliosis ,Medicine (General) ,R5-920 - Abstract
Eighty-two patients seeking consultation for long-term sequalae after suspected tick-borne illness were consecutively tested for Borrelia miyamotoi antibodies using a recombinant glycerophosphodiester phosphodiesterase (GlpQ) enzyme immunoassay. Twenty-one of the 82 patients (26%) tested positive on the GlpQ IgG ELISA. Nearly all of the patients (98%) had no prior B. miyamotoi testing, indicating that clinicians rarely test for this emerging tick-borne pathogen. Compared to patients who solely tested positive for Lyme disease antibodies, patients with B. miyamotoi antibodies presented with significantly more sleepiness and pain. A prospective study is needed to ascertain the relationship between the presence of B. miyamotoi antibodies and persistent symptoms.
- Published
- 2020
- Full Text
- View/download PDF