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Background: Orthodontic force application to the teeth is responsible for a series of biological responses in the bone and dentin, which lead to some alterations of the mineral density of the tissues. Our objective was determine, through cone-beam computed tomography (CBCT), the mineral density of the apical third of the roots of the upper central incisors and of the periapical bone portion surrounding these teeth, in patients submitted to orthodontic treated and untreated individuals., Material/methods: 30 untreated individuals and 15 treated ones (treatment cessation at least 1 year before the study) underwent CBCT. Mineral density was assessed in the apical third of the root of the upper central incisors and in the alveolar bone in the periapical region of these teeth. In order to reduce CBCT-related mineral density variability, we standardized the cone-beam tomography device, the image-acquisition settings and the field of view positioning and size. Student's t test was used for the analyses., Results: bone mineral density (BMD) and root mineral density (RMD), in Hounsfield Units, were 674.84 and 1282.26 for the untreated group and 630.28 and 1370.29 for the treated group, respectively. The differences between the group means were statistically significant for RMD (p<0.05)., Conclusions: untreated individuals had a significant lower mean RMD in comparison with those submitted to orthodontic treatment.

Introduction: The aims of this study were to correlate the clinical and radiographic stability of titanium miniscrews when used as orthodontic anchorage for maxillary canine retraction and to assess bone quality., Methods: Thirty titanium miniscrews were placed in 15 consecutive patients (8 male, 7 female; age range, 12 years 5 months-32 years 11 months) as orthodontic anchorage. Orthodontic loads were applied immediately after miniscrew placement (T1) with a nickel-titanium closing coil spring. The initial estimated load was 200 g. The bone quality in each region of interest was determined by multi-slice computed tomography., Results: Bone mineral density (BMD) values ranged from 167 HU to 660.80 HU (mean, 420.63 HU). The specific regions had a mean close to the maximum value of a previously established scale for the posterior region of the maxilla (0-500 HU). The paired t test showed a statistically significant difference (P = 0.450) when the means of the differences between the right and left sides were compared. Twelve of the 15 subjects had significantly greater maxillary BMD on the right side. Linear regression also showed a low correlation between the 2 sides (P = 0.097). Clinically, the success index was 100%. Although 2 miniscrews were removed from 1 patient because of severe gingival inflammation with purulent secretion, none of the 28 remaining miniscrews showed any mobility after 90 days (T2). Comparisons of the means at T1 and T2 showed no statistically significant differences in these distances: between nasion and the miniscrew head, between orbitale and the miniscrew head, and between nasion and orbitale, assessed through cephalometric tracings made on lateral oblique radiographs (45 degrees ), pointing to the stability of the 28 miniscrews during the 90-day observation period. BMD values of all subjects were within the normal range of an established scale, and even close to maximum values., Conclusions: The regions between the maxillary second premolars and first molars, and mesial to the maxillary second premolars, are safe as far as bone quality is concerned for miniscrew placement during the first 90 days of canine distalization. A good surgical technique and appropriate planning for miniscrew placement, inflammation control, and adequate oral hygiene are fundamental to the success of this new anchorage system during maxillary canine distalization.