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The study aimed at evaluating how sires, classified for their additive genetic effects on residual feed intake (RFI) of ad libitum-fed progeny, influence growth performance, tissue accretion, and gain composition in restricted-fed offspring (96–168 kg body weight, BW). A total of 416 purebred C21 Goland pigs, offspring of 23 sires, were randomly allocated to three feeding groups: ad libitum, restricted medium-protein, or restricted low-protein. Empty BW, body lipid mass and body protein mass were estimated from individual BW and backfat measures using literature equations. Residuals of a linear regression of average daily feed intake on average empty BW, body lipid and protein daily gains were used as estimates of individual RFI in ad libitum-fed pigs. Additive genetic effects of sires on RFI of ad libitum-fed pigs were estimated with a linear animal model and solutions of the model were used to allocate the sires to low- (LRFI), medium- (MRFI), or high-RFI (HRFI) groups. Restricted-fed progeny of LRFI sires exhibited reduced average daily feed intake (-3%) compared to MRFI and HRFI progeny. This indicates that LRFI progeny make a more efficient use of energy intake and implies that variation in RFI across families, assessed under ad libitum feeding, is related to the across-family variation in feed efficiency detected under restricted feeding. LRFI progeny exhibited also a lower feed conversion ratio (-11%), partially resulting from of a 3% increase in growth rate compared with HRFI. Thus, LRFI progeny consumed less feed, while growing at a similar or slightly higher rate than MRFI or HRFI. No significant differences across sire classes were observed for daily tissue accretion and gain composition. Hence, we can hypothesise that efficient sires would not affect carcass leanness of heavy pig progeny fed restricted. [ABSTRACT FROM AUTHOR]

Child maltreatment poses not only immediate danger, but as a type of toxic stress, it creates higher risk of biologic dysfunction later in life. Pediatricians are in a unique position to diagnose child maltreatment, but they need evidence-based guidance for when to initiate screening when injury is occult. In this retrospective cohort study of 855 pediatric patients diagnosed with child maltreatment, researchers explored whether type or number of diagnoses was associated with abnormal pediatric weight in either direction. Diagnoses and weight assessed at intake were extracted from medical records for analysis. Statistically significant associations were found between weight classification and child maltreatment type as well as diagnosis count. Neglect was most frequently diagnosed, and children with ≥2 diagnoses were more likely to be classified as underweight, overweight, or obese. Findings support abnormal pediatric weight as a biologic signal of adversity that warrants safety screening in the clinical setting. [ABSTRACT FROM AUTHOR]

Objective: The study investigated interpersonal distance in patients with anorexia nervosa (AN), focussing on the role of other's facial expression and morphology, also assessing physiological and subjective responses. Method: Twenty‐nine patients with AN and 30 controls (CTL) were exposed to virtual characters either with an angry, neutral, or happy facial expression or with an overweight, normal‐weight, or underweight morphology presented either in the near or far space while we recorded electrodermal activity. Participants had to judge their preferred interpersonal distance with the characters and rated them in terms of valence and arousal. Results: Unlike CTL, patients with AN exhibited heightened electrodermal activity for morphological stimuli only, when presented in the near space. They also preferred larger and smaller interpersonal distances with overweight and underweight characters respectively, although rating both negatively. Finally, and similar to CTL, they preferred larger interpersonal distance with angry than neutral or happy characters. Discussion: Although patients with AN exhibited behavioural response to emotional stimuli similar to CTL, they lacked corresponding physiological response, indicating emotional blunting towards emotional social stimuli. Moreover, they showed distinct behavioural and physiological adjustments in response to body shape, confirming the specific emotional significance attached to body shape. Highlights: Patients with anorexia nervosa (AN) show a regulation of interpersonal distances to social emotional stimuli similar to healthy controls (CTL) but lack the corresponding physiological response.Patients with AN, not CTL, prefer shorter interpersonal distance with underweight social stimuli and larger interpersonal distance with overweight ones and show increased physiological response to both of them.Patients with AN show a bias towards morphological rather than emotional cues when processing information to optimise social interaction. [ABSTRACT FROM AUTHOR]

Cognitive decline and comorbid conditions commonly co-occur, and these conditions can affect cognitive health. We aimed to estimate the prevalence of cognitive impairment (CI) according to weight status and to evaluate the associations between CI, weight status and comorbid conditions in adults of 55 years and older. The Abbreviated Mental Test Score (AMTS) was used. Logistic regressions were performed. Overall, 415 individuals were included. The mean age was 75.7 ± 10.1 years, and the mean BMI was 26.2 ± 6.9 kg/m2. The prevalence of CI was 20.7% in the whole study group and 31%, 24.8%, 17.7% and 10.2% in underweight, normal weight, overweight and obese individuals, respectively; p < 0.004. The low folate, vitamin D and prealbumin levels were more frequently found in individuals with CI compared with those without CI. Compared with the obese individuals, a higher odds ratio of prevalent CI was noted for underweight individuals OR 3.89 (95% CI 1.54–9.80); p = 0.004. Additionally, male gender, older age, stroke, having three or more comorbid conditions and findings of undernutrition were significantly associated with CI. Being underweight was associated with an increased risk of CI. Prevention strategies including the monitoring of nutritional status may help to prevent cognitive decline and promote healthy aging. [ABSTRACT FROM AUTHOR]

This study aimed to identify differences among body mass index (BMI) categories of older family caregivers (=60 years) and their care recipients (=65 years). Secondly, this study aimed to examine group differences and factors associated with weight change during a nutrition and oral health intervention. This secondary analysis of a randomized controlled trial (ClinicalTrial.gov (NCT04003493)) involved individually tailored nutritional guidance from a clinical nutritionist and oral health guidance from a dental hygienist. Baseline BMI differences were analyzed, followed by further analyses of group differences and associated factors of weight change over a 6-month period using generalized estimating equations. Among the participants (113 family caregivers and 107 care recipients), 36.3% and 35.1% were overweight (BMI >29 kg/m²), while 18.6% and 21.6% were underweight (BMI <24 kg/m²) at baseline, respectively. For family caregivers differences in BMI categories included age, mid-arm and calf circumferences, and plasma prealbumin concentration. For care recipients differences were observed in medication use, mid-arm and calf circumferences, Mini Nutritional Assessment scores, physical function, and number of teeth. During the 6-month intervention, there were no differences in weight change between intervention and control groups for both caregivers and care recipients. Factors significantly associated (p < 0.05) with weight loss included female sex for both caregivers and care recipients, and frailty for caregivers. Family caregivers' characteristics were not significantly associated with weight change in their care recipients. In conclusion, being overweight is a prevalent among older family caregivers and care recipients. Factors such as age, medication use, physical function, number of teeth, and Mini Nutritional Assessment scores varied across BMI categories. Female sex was associated with weight loss in both older family caregivers and care recipients, and frailty was associated with weight loss in caregivers. However, the characteristics of family caregivers did not explain the weight loss of their care recipients. [ABSTRACT FROM AUTHOR]

Background: Recognition of atypical anorexia nervosa (AAN) has challenged underweight as a defining factor of illness severity in anorexia nervosa (AN). The present study aimed to compare rates of medical instability in adolescents with underweight (AN) and non‐underweight (AAN) anorexia nervosa. Methods: The study examined assessment data from specialist eating disorder services in the UK between January and December 2022. Participants (n = 205) aged 11–18 years were recruited across eight eating disorder clinics and diagnosed with AN (n = 113) or AAN (n = 92) after clinical assessment. Parameters associated with risk of medical instability were compared between AN and AAN groups, using t tests and regression analysis. Results: Rates of bradycardia and hypotension did not differ significantly between AN and AAN groups (p = 0.239 and p = 0.289). Although white blood cell counts were lower in the AN group, rates of leukopaenia could not be statistically compared as a result of there being too few counts in at least one group. No incidences of hypophosphataemia were found in the sample. A significant regression equation was found for percentage median body mass index, but not rate of weight loss, as a predictor of blood pressure, serum phosphorous and magnesium. Conclusions: Our findings indicate that medical instability occurs across a range of body weights in young people with AN and AAN. Although certain parameters of risk such as blood pressure, serum phosphorous and magnesium may be worsened at lower weight, both AN and AAN are serious mental health conditions that can lead to medical instability. Highlights: The study compared rates of medical instability in adolescents with underweight (AN) and non‐underweight (AAN) anorexia nervosa.The findings support the conclusion that, although certain parameters of risk (e.g., blood pressure) may be worsened by lower weight, both AN and AAN are serious illnesses that can lead to medical compromise. [ABSTRACT FROM AUTHOR]

Objectives: To examine the association between life‐course body silhouette changes and oral conditions in adulthood. Methods: At study recruitment (2008–2012), 5430 adults underwent a full‐mouth clinical examination and recalled their body silhouettes at ages 8, 15, 25, 35 and 45. Life‐course trajectories of body silhouettes were computed using group‐based trajectory modelling. Gingival inflammation, dental plaque, masticatory units, numbers of healthy, missing, decayed and filled teeth at study recruitment were clustered. The associations between body silhouette trajectories and clusters of oral conditions were assessed by multinomial logistic regression. Results: The final analysis included 4472 participants. Five body silhouette trajectories were established: lean‐stable (30.0%), lean‐increased (19.3%), moderate stable (18.1%), lean‐marked increased (25.8%) and heavy stable (6.7%). Three clusters of oral conditions were identified: optimal oral health and preserved masticatory capacity (70.0%, cluster 1), moderate oral health and moderately impaired masticatory capacity (25.4%, cluster 2) and poor oral health and severely impaired masticatory capacity (4.7%, cluster 3). Participants with a lean‐increased trajectory were 58% more likely than those with a lean‐stable trajectory to be in cluster 3 (aOR 1.58 [95% CI 1.07; 2.35]) relative to cluster 1, independently of covariates measured at study recruitment and including age, sex, smoking, socioeconomic status, BMI, hypertension, type 2 diabetes, cholesterol and triglycerides. Conclusions: A life‐course lean‐increased body silhouette trajectory is associated with higher likelihood of poor oral health and severely impaired masticatory capacity in adulthood. [ABSTRACT FROM AUTHOR]

Objective Despite an increase in twin pregnancies in recent decades, the Institute of Medicine twin weight gain recommendations remain provisional and provide no guidance for the pattern or timing of weight change. We sought to characterize gestational weight change trajectory patterns and examine associations with birth outcomes in a cohort of twin pregnancies. Study Design Prenatal and delivery records were examined for 320 twin pregnancies from a maternal–fetal medicine practice in Austin, TX 2011-2019. Prenatal weights for those with >1 measured weight in the first trimester and ≥3 prenatal weights were included in analyses. Trajectories were estimated to 32 weeks (mean delivery: 33.7 ± 3.3 weeks) using flexible latent class mixed models with low-rank thin-plate splines. Associations between trajectory classes and infant outcomes were analyzed using multivariable Poisson or linear regression. Results Weight change from prepregnancy to delivery was 15.4 ± 6.3 kg for people with an underweight body mass index, 15.4 ± 5.8 kg for healthy weight, 14.7 ± 6.9 kg for overweight, and 12.5 ± 6.4 kg for obesity. Three trajectory classes were identified: low (Class 1), moderate (Class 2), or high gain (Class 3). Class 1 (24.7%) maintained weight for 15 weeks and then gained an estimated 6.6 kg at 32 weeks. Class 2 (60.9%) exhibited steady gain with 13.5 kg predicted total gain, and Class 3 (14.4%) showed rapid gain across pregnancy with 21.3 kg predicted gain. Compared to Class 1, Class 3 was associated with higher birth weight z -score (β = 0.63, 95% confidence interval [CI]: 0.31,0.96), increased risk for large for gestational age (IRR = 5.60, 95% CI: 1.59, 19.67), and birth <32 weeks (IRR = 2.44, 95% CI: 1.10, 5.4) that was attenuated in sensitivity analyses. Class 2 was associated with moderately elevated birth weight z -score (β = 0.24, 95% CI: 0.00, 0.48, p = 0.050). Conclusion Gestational weight change followed a low, moderate, or high trajectory; both moderate and high gain patterns were associated with increased infant size outcomes. Optimal patterns of weight change that balance risk during the prenatal, perinatal, and neonatal periods require further investigation, particularly in high-risk twin pregnancies. Key Points A majority gained weight below IOM twin recommendations. Three patterns of GWC across pregnancy were identified. Moderate or high GWC was associated with infant size. [ABSTRACT FROM AUTHOR]

Background: Patients with anorexia nervosa (AN) show overgeneralization of memory (OGM) when generating autobiographical episodes related to food and body shape. These memories are central for the construction of a coherent self‐concept, interpersonal relationships, and problem‐solving abilities. The current study aims to investigate changes in autobiographical memory following weight gain. Methods: OGM was assessed with an adapted version of the Autobiographical Memory Test including food‐, body‐, depression‐related, and neutral cues. N = 41 female patients with AN (28 restricting‐, 13 binge‐eating/purging‐subtype; mean disease duration: 4.5 years; mean BMI: 14.5 kg/m2) and N = 27 healthy controls (HC) were included at baseline. After inpatient treatment (mean duration: 11 weeks), 24 patients with AN and 24 age‐matched HC were reassessed. Group differences were assessed using independent samples t‐tests for cross‐sectional comparisons and repeated measures ANOVAs for longitudinal data. Results: At baseline, patients with AN generated significantly fewer specific memories than HC, independent of word category (F(1.66) = 27.167, p < 0.001). During inpatient stay, the average weight gain of patients with AN was 3.1 body mass index points. At follow‐up, patients with AN showed a significant improvement in the number of specific memories for both depression‐related and neutral cues, but not for food‐ and body‐related cues. Conclusions: Generalised OGM (i.e., independent of word category) in patients with AN before weight restoration may be a general incapacity to recall autobiographical memory. After weight gain, the previously well‐studied pattern of eating disorder‐related OGM emerges. The clinical relevance of the continuing disorder‐related OGM in patients with AN after weight gain is discussed. Highlights: 'Overgeneral Memory' (OGM) in severely underweight patients (mean body mass index = 14.5 kg/m2) with anorexia nervosa (AN) might be a state marker in the form of a general incapacity to recall autobiographical memories, regardless of emotional valence.Reduced symptoms of depression in patients with AN after weight gain, compared with the beginning of inpatient treatment, may be an indication of an overall improvement in mental health as negative memories become more specific.The persisting eating disorder‐related OGM after weight gain might be a maintaining factor of AN facilitating relapse and could also reflect increased dysfunctional emotion processing despite decreased eating disorder symptoms: functional avoidance might be a protective mechanism in the form of less confrontation with eating disorder‐related content through generalised memories. [ABSTRACT FROM AUTHOR]

Background: Food insecurity significantly impacts children's health, affecting their development across cognitive, physical, and socio-emotional dimensions. This study explores the impact of food insecurity among children aged 6 months to 5 years, focusing on nutrient intake and its relationship with various forms of malnutrition. Methods: Utilizing machine learning algorithms, this study analyzed data from 819 children in the West Bank to investigate sociodemographic and health factors associated with food insecurity and its effects on nutritional status. The average age of the children was 33 months, with 52% boys and 48% girls. Results: The analysis revealed that 18.1% of children faced food insecurity, with household education, family income, locality, district, and age emerging as significant determinants. Children from food-insecure environments exhibited lower average weight, height, and mid-upper arm circumference compared to their food-secure counterparts, indicating a direct correlation between food insecurity and reduced nutritional and growth metrics. Moreover, the machine learning models observed vitamin B1 as a key indicator of all forms of malnutrition, alongside vitamin K1, vitamin A, and zinc. Specific nutrients like choline in the "underweight" category and carbohydrates in the "wasting" category were identified as unique nutritional priorities. Conclusion: This study provides insights into the differential risks for growth issues among children, offering valuable information for targeted interventions and policymaking. [ABSTRACT FROM AUTHOR]

Introduction: The importance of body composition and sarcopenia is wellrecognized in cancer patient outcomes and treatment tolerance, yet routine evaluations are rare due to their time-intensive nature. While CT scans provide accurate measurements, they depend on manual processes. We developed and validated a deep learning algorithm to automatically select and segment abdominal muscles [SM], visceral fat [VAT], and subcutaneous fat [SAT] on CT scans. Materials and Methods: A total of 352 CT scans were collected from two cancer centers. The detection of the third lumbar vertebra and three different body tissues (SM, VAT, and SAT) were annotated manually. The 5-fold cross-validation method was used to develop the algorithm and validate its performance on the training cohort. The results were validated on an external, independent group of CT scans. Results: The algorithm for automatic L3 slice selection had a mean absolute error of 4 mm for the internal validation dataset and 5.5 mm for the external validation dataset. The median DICE similarity coefficient for body composition was 0.94 for SM, 0.93 for VAT, and 0.86 for SAT in the internal validation dataset, whereas it was 0.93 for SM, 0.93 for VAT, and 0.85 for SAT in the external validation dataset. There were high correlation scores with sarcopenia metrics in both internal and external validation datasets. Conclusions: Our deep learning algorithm facilitates routine research use and could be integrated into electronic patient records, enhancing care through better monitoring and the incorporation of targeted supportive measures like exercise and nutrition. [ABSTRACT FROM AUTHOR]

This study aimed to identify critical risk factors for childhood malnutrition and inform targeted interventions. Childhood malnutrition remains a pressing concern in the coastal regions of Bangladesh. Data were extracted from the latest Bangladesh Demographic and Health Survey 2017–2018 and children aged 0–59 months and their mothers aged 15–49 years from 17 coastal districts were included as study population in this study. We performed multivariable logistic regression model to determine the risk factors and a total 2153 children were eligible for the analysis. Stunting, wasting and underweight prevalence was 31.4%, 8.5% and 21.1% respectively. Stunting was more common in children aged 24–35 months with compared to their younger counterparts [adjusted odds ratio (AOR) = 3.32, 95% confidence interval (CI): 2.35–4.67]. Children to mothers with higher education exhibited 69% (AOR = 0.31, 95% CI: 0.18–0.52) lower risk of stunting compared to those with no education. Similarly, children in poorest and poorer households had 2.2 and 1.83 times higher odds of stunting respectively than those in the richest households. Children born to obese mothers (compared to normal) were 34% less likely to be stunted (AOR = 0.66, 95% CI: 0.51–0.85). Children who had fever and underweight mothers reported wasting. Increasing child age, low maternal education, poorest wealth index, unimproved toilet facilities and childhood morbidity were identified as significant risk factors for underweight. Results support the requirement of effective and appropriate interventions for this particular region considering the identified risk factors to reduce childhood malnutrition in Bangladesh. [ABSTRACT FROM AUTHOR]

Summary: Background: Obesity is prevalent among children and adults. Yet, understanding the relationship between parent and child weight trajectories is limited. Objective: (1) Examine the association between parent/child undesirable body mass index (BMI) category change. (2) Assess whether parental BMI category predicts child modified BMI z‐score (mBMIz) annual change. Methods: We conducted a cross‐sectional study of weight trajectories of 3821 parent–child dyads between March 2020 and December 2021 within the NYC Health + Hospitals system. Undesirability of child and parental BMI category change and the magnitude of mBMIz change by parental BMI are analysed. Results: Of 3821 children (mean [SD] baseline age, 9.84 [3.51]), 1889 were female. Of the 3220 parents (mean [SD] baseline age, 39.9 [8.51]), 2988 were female. Most children (53.52%) and parents (81.94%) presented with overweight and obesity. Undesirable BMI change in children was associated with concordant change in parents (adjusted OR: 1.7, 95% CI [1.45, 2.01], adjusted p < 0.001). Children of parents with obesity (adjusted coef: 0.076, 95% CI [0.004, 0.147], p < 0.038) and severe obesity (adjusted coef: 0.1317, 95% CI [0.024, 0.239], adjusted p < 0.016) demonstrated greater change in mBMIz than those of parents with normal weight or underweight. Conclusion: Parents and children have concordant weight trajectories, and public health interventions targeting both populations are essential. [ABSTRACT FROM AUTHOR]

We aimed to explore and analyse the dietary intake patterns of 3‐6 year‐old children left behind by one or both parents and to assess their associations with body mass index (BMI) and the prevalence of childhood anaemia in rural Anhui, eastern China. We used random cluster sampling to recruit rural children aged 3–6 years in two rural areas in Anhui province. Sociodemographic information and dietary intake were collected by self‐reported questionnaires. Height, weight and prevalence of anaemia were measured by trained nurses blinded to parental migration status. Factor analysis was applied to determine that major dietary patterns, binary logistic regression and generalised linear regression were used to explore the associations between anaemia and BMI Z‐score with dietary patterns. Of 1720 children aged 3–6 years, 236 were left by both parents and 388 were left by a single parent. The prevalence of stunting and underweight among left‐behind children with migration of both parents (BLBC) was significantly higher than that of non‐left‐behind children (NLBC). Three dietary patterns—"grain–vegetable," "meat–egg" and "fast food–sweet"—were identified in our study, and the total variance explained was 46.9%. The meat–egg dietary pattern was associated with a decreased risk of anaemia after adjustment for confounding factors in the left‐behind children with migration of both parents (BLBC), left‐behind children with single parent migration (SLBC) and non‐left‐behind children (NLBC) groups. After adjusting for confounding factors, the fast food–sweet dietary pattern was found to be associated with an increased risk of anaemia (OR [95% CI]: Q4: 2.21 [1.14, 4.57], p = 0.034). In addition, children with obesity had a lower intake of vegetables and fruits (β = −0.08, 95% CI: −0.13, −0.02) compared with children with a normal weight. In conclusion, there are correlations between different types of parental migration and children's nutritional status in rural Anhui. The meat–egg dietary pattern may have a preventive effect on anaemia in comparison with other dietary patterns, irrespective of whether children are left behind or not. Children with overweight and obesity had a higher intake of pork and red meat and snacks compared with children with normal BMI. [ABSTRACT FROM AUTHOR]

Nicotinamide phosphoribosyltransferase (Nampt) is an adipocytokine that is elevated in obesity, type 2 diabetes and increased levels are associated with inflammatory processes. Nampt serum concentrations have been suggested to follow a diurnal rhythm peaking in the afternoon in lean males. However, no data exists regarding the effects of gender and body weight. We measured Nampt serum levels over 24 h in a cohort of healthy individuals living with either normal weight or obesity. Furthermore, effects of meals, oral glucose tolerance test and physical exercise on Nampt concentrations were evaluated. Correlation analyses to other hormonal- and lab parameters and anthropometric measurements were performed. Nampt showed a diurnal rhythm with increased levels at daytime and a peak in the early afternoon. This diurnal rhythm was significant for all groups but obese males. The Nampt amplitude, measured both relatively and absolutely, was significantly higher in females than in males. Meals did not influence Nampt serum levels, whereas physical exercise and an OGTT did significantly influence Nampt serum levels. In conclusion, we found gender specific differences in Nampt amplitude and coefficient variation with both being higher in females. The circadian rhythm of Nampt was independent of gender in healthy lean individuals, whereas it was disturbed in men with obesity. [ABSTRACT FROM AUTHOR]

Background: Children with underweight in the first 2 years have lower body mass index z‐score (zBMI) and height‐for‐age z‐score (HAZ) in later childhood. It is not known if underweight in the first 2 years is associated with nutrition risk in later childhood. Objective: (1) Determine the relationship between underweight (zBMI < −2) in the first 2 years and nutrition risk measured by the Nutrition Screening for Toddlers and Preschoolers (NutriSTEP) score from 18 months to 5 years. (2) Explore the relationship between underweight in the first 2 years and the NutriSTEP subscores for eating behaviours and dietary intake from 18 months to 5 years. Methods: This was a prospective study, including healthy full‐term children in Canada aged 0–5 years. zBMI was calculated using measured heights and weights and the WHO growth standards. NutriSTEP score was measured using a parent‐completed survey and ranged from 0 to 68. Nutrition risk was defined as a score ≥21. Linear mixed effects models were used. Results: Four thousand nine hundred twenty‐nine children were included in this study. At enrolment, 51.9% of participants were male. The prevalence of underweight children was 8.8%. Underweight in the first 2 years was associated with higher NutriSTEP (0.79, 95% CI: 0.29,1.29), higher eating behaviour subscore (0.24, 95% CI: 0.03, 0.46) at 3 years and higher odds of nutrition risk (OR: 1.39, 95% CI: 1.07,1.82) at 5 years. Conclusions: Children with underweight in the first 2 years had higher nutrition risk in later childhood. Further research is needed to understand the factors which influence these relationships. Key points: In this prospective cohort study of 4929 children aged 0–5 years, children with underweight in the first 2 years of life had higher odds of nutrition risk at 5 years of age compared to children without underweight in the first 2 years (p = 0.02). Further research is needed to understand the factors which influence these relationships. [ABSTRACT FROM AUTHOR]

Previous studies suggest that there is discordance between actual weight status and body-weight perception. This fact has implications when it comes to designing public health interventions. The aim of this study was to estimate the prevalence of the different categories of weight status and body-weight perception and to analyse their concordance in a representative Spanish population sample. Cross-sectional study. Data were sourced from the 2018 Galician Risk Behaviour Data System, with the target population being all persons aged 16 years and above. We collected data on self-perceived body weight and assessed weight status on the basis of body mass index (BMI). BMI was estimated using self-reported measures of weight and height. To estimate concordance, Cohen's kappa coefficient, both unweighted and weighted with Cicchetti weights, was calculated. Data were obtained for 7853 individuals aged 16 years and above, whereas the overall unweighted concordance was 0.393 (95%CI: 0.377–0.409), with an agreement percentage of 61.6%, weighted concordance was 0.503 (0.490–0.517), with an agreement percentage of 86.6%. The highest concordance between self-perceived body weight and weight status was observed in women. By age group, the highest concordance was observed in the youngest group (16–24 years) for the BMI categories of underweight and overweight, and in the 45–64 age group for the category of obesity. The results highlight the existence of differences between self-perceived body weight and weight status, according to sex and age. [ABSTRACT FROM AUTHOR]

Objective: For adolescents, DSM‐5 differentiates anorexia nervosa (AN) and atypical AN with the 5th BMI‐centile‐for‐age. We hypothesized that the diagnostic weight cut‐off yields (i) lower weight loss in atypical AN and (ii) discrepant premorbid BMI distributions between the two disorders. Prior studies demonstrate that premorbid BMI predicts admission BMI and weight loss in patients with AN. We explore these relationships in atypical AN. Method: Based on admission BMI‐centile < or ≥5th, participants included 411 female adolescent inpatients with AN and 49 with atypical AN from our registry study. Regression analysis and t‐tests statistically addressed our hypotheses and exploratory correlation analyses compared interrelationships between weight loss, admission BMI, and premorbid BMI in both disorders. Results: Weight loss in atypical AN was 5.6 kg lower than in AN upon adjustment for admission age, admission height, premorbid weight and duration of illness. Premorbid BMI‐standard deviation scores differed by almost one between both disorders. Premorbid BMI and weight loss were strongly correlated in both AN and atypical AN. Discussion: Whereas the weight cut‐off induces discrepancies in premorbid weight and adjusted weight loss, AN and atypical AN overall share strong weight‐specific interrelationships that merit etiological consideration. Epidemiological and genetic associations between AN and low body weight may reflect a skewed premorbid BMI distribution. In combination with prior findings for similar psychological and medical characteristics in AN and atypical AN, our findings support a homogenous illness conceptualization. We propose that diagnostic subcategorization based on premorbid BMI, rather than admission BMI, may improve clinical validity. Public significance: Because body weights of patients with AN must drop below the 5th BMI‐centile per DSM‐5, they will inherently require greater weight loss than their counterparts with atypical AN of the same sex, age, height and premorbid weight. Indeed, patients with atypical AN had a 5.6 kg lower weight loss after controlling for these variables. In comparison to the reference population, we found a lower and higher mean premorbid weight in patients with AN and atypical AN, respectively. Considering previous psychological and medical comparisons showing little differences between AN and atypical AN, we view a single disorder as the most parsimonious explanation. Etiological models need to particularly account for the strong relationship between weight loss and premorbid body weight. [ABSTRACT FROM AUTHOR]

Background: Adolescent mental health problems are becoming increasingly prevalent, and there are correlations between weight-related concerns and adolescent mental health. The aim of this study is to explore the association between three weight-related factors (actual weight, weight perception, and weight teasing) and mental health problems (depressive symptoms, anxiety symptoms, and loneliness) in Chinese adolescents. Methods: 10,070 adolescents between the ages of 11–18 from schools in Shanghai, China were selected using a stratified random cluster sampling method. Self-reported questionnaires were collected to investigate weight-related factors and mental health problems. Logistic regression analysis was used to examine the relationship. Results: The prevalence of depressive symptoms, loneliness, mild anxiety symptoms, and moderate to severe anxiety symptoms among adolescents were 18.0%, 53.8%, 26.5%, and 12.3%, respectively, with a higher prevalence found in females. After adjusting for weight perception and weight teasing, actual weight had no harmful impact on adolescents' mental health. Adolescents' perception of being overweight increased the risk of depressive symptoms, loneliness, mild anxiety symptoms, and moderate to severe anxiety symptoms, while the perception of being underweight had a similar but more profound impact (depressive symptoms OR = 1.590, 95% CI: 1.342–1.883; loneliness OR = 1.537, 95% CI: 1.353–1.746; mild anxiety symptoms OR = 1.368, 95% CI: 1.178–1.589; moderate to severe anxiety symptoms OR = 1.780, 95% CI: 1.449–2.186). Experiencing weight teasing more than once a year had a greater effect on adolescents' mental health, especially among adolescents with overweight/obesity (depressive symptoms OR = 2.970, 95% CI: 2.325–3.793; loneliness OR = 3.839, 95% CI: 3.119–4.727; mild anxiety symptoms OR = 2.822, 95% CI: 2.236–3.562; moderate to severe anxiety symptoms OR = 5.212, 95% CI: 3.846–7.065). Conclusions: The prevalence of mental health problems among adolescents was high, especially loneliness. Weight perception and weight teasing, but not the actual weight, independently influenced adolescent mental health. [ABSTRACT FROM AUTHOR]

Sarah Jane Palmer describes the powerful impact diet can have on the capability of a wound to heal itself. A wide range of nutrients can improve healing, yet malnutrition in everyday diet, regardless of a person's weight, can significantly delay or prevent healing. This article explores wound types, such as chronic wounds and burns, and discusses immunonutrition. [ABSTRACT FROM AUTHOR]

Background and Objectives: Nutrition literacy is a concept that improves individuals' diet quality, and quality of life and contributes to enhancing their general health by using and interpreting nutrition-related information correctly. This study purposed to determine the nutritional literacy and quality of life levels of university students and relate them with anthropometric measurements. Materials and Methods: This is a cross-sectional study and was conducted with 374 university students over the age of 18 at a state university. Nutrition literacy was assessed by using the Evaluation Instrument of Nutrition Literacy on Adults (EINLA), and quality of life was evaluated with the World Health Organization's Quality of Life Questionnaire (Turkish_WHOQOL-BREF). Waist, middle-upper arm, neck circumference, body weight, and height were measured in accordance with appropriate techniques by researchers. Independent t and One-Way ANOVA tests were used to determine differences between two and more than two mean values. Pearson correlation analysis was used to detect relationships between scores of total EINLA, its sections, total Turkish_WHOQOL-BREF and its dimensions, and other variables. Results: The mean EINLA and WHOQOL-BREF scores of the participants were 25.3±4.7 (borderline) and 54.3±15.1, respectively. While the EINLA score varied according to gender, faculty (health sciences vs others), and degree (1 to 4), the WHOQOL-BREF score varied according to gender and living place (home vs dormitory). EINLA and WHOQOL-BREF scores of BMI (underweight to obese), waist circumference, and neck circumference (normal vs at risk) groups were not different. It was found positive significant relationships between the second section of EINLA (reading comprehension and interpretation) and psychological health, the third section of EINLA (food groups), and social relationships (p<0.05). Conclusion: Nutrition literacy, anthropometric measurements, and quality of life of university students are affected by a multifactorial situation. [ABSTRACT FROM AUTHOR]

Objective: The goal of this follow‐up to a randomized proof‐of‐concept study was to determine if targeting body shape concern (BSC) has a clinically significant impact on long‐term weight change among adult women of higher body weight with BSC. A secondary aim was to observe the maintenance of body image improvements during follow‐up. Method: In the original 4‐week trial, women were randomized to behavioral weight loss recommendations alone (control; n = 15) or combined with the evidence‐based body project intervention (n = 17). All participants were directed to continue monitoring diet and exercise through Week 8. The current analysis focused on follow‐up data collected on weight, BSC, internalized weight bias, internalized thin ideal, and body appreciation at 8 weeks, 6 months, and 12 months. Percent weight change was calculated from baseline and compared against clinical milestones of −2.5% and −5%. An intent‐to‐treat approach was used for individuals lost to follow‐up (n = 11). Results: Body project participants achieved the clinically significant target of −2.5% weight loss by 12 months. Control participants did not reach the milestone and regained lost weight at 12 months. Neither condition reached the 5% clinical target. Both groups experienced improved body image, but body project participants maintained a greater magnitude of improvement in all measures except internalized thin ideal at 12 months. Conclusion: The current study provides preliminary evidence that targeting BSC among women with BSC who want to lose weight may improve long‐term weight loss. Further intervention development and testing are warranted. Public Significance: The results of this study suggest that targeting negative body image among adult women with high BSC might be a pathway to improve long‐term weight loss in behavioral weight management. This is aligned with precision medicine priorities to optimize weight‐related health care. [ABSTRACT FROM AUTHOR]

The study aimed to explore the association between body mass index (BMI) and cognitive function among older adults in India. Cross-sectional data on 21,000 older adults aged 60 years and older from the first wave of the Longitudinal Ageing Study of India (LASI), conducted in India during 2017-18, were used. Bivariate analysis and multivariate linear regression models were applied. The cognition tests include memory, orientation, arithmetic function, executive function, and object naming. The mean overall cognition score was 24.6 in the study population. Further, BMI status showed a significant and positive association with cognition. The association of underweight with poor cognition (β=-0.72; 95% CI = −0.89, −0.54) whereas overweight (β = 0.57; 95% CI = 0.39, 0.75) and obese (β = 0.97; 95% CI = 0.68, 1.26) with better cognition remained statistically significant after adjusting for sociodemographic, health-related behavior, and health covariates. The mean cognition score of female older adults was always lower than male older adults with normal BMI, irrespective of their BMI categories. This study shows that an underweight BMI is associated with poor cognition in both male and female older adults. In the context of providing health care for older individuals, underweight individuals should be given more attention in India. [ABSTRACT FROM AUTHOR]

Background: Anorexia nervosa (AN) is characterized by sizable, widespread gray matter (GM) reductions in the acutely underweight state. However, evidence for persistent alterations after weight-restoration has been surprisingly scarce despite high relapse rates, frequent transitions to other psychiatric disorders, and generally unfavorable outcome. While most studies investigated brain regions separately (univariate analysis), psychiatric disorders can be conceptualized as brain network disorders characterized by multivariate alterations with only subtle local effects. We tested for persistent multivariate structural brain alterations in weight-restored individuals with a history of AN, investigated their putative biological substrate and relation with 1-year treatment outcome. Methods: We trained machine learning models on regional GM measures to classify healthy controls (HC) (N = 289) from individuals at three stages of AN: underweight patients starting intensive treatment (N = 165, used as baseline), patients after partial weight-restoration (N = 115), and former patients after stable and full weight-restoration (N = 89). Alterations after weight-restoration were related to treatment outcome and characterized both anatomically and functionally. Results: Patients could be classified from HC when underweight (ROC-AUC = 0.90) but also after partial weight-restoration (ROC-AUC = 0.64). Alterations after partial weight-restoration were more pronounced in patients with worse outcome and were not detected in long-term weight-recovered individuals, i.e. those with favorable outcome. These alterations were more pronounced in regions with greater functional connectivity, not merely explained by body mass index, and even increases in cortical thickness were observed (insula, lateral orbitofrontal, temporal pole). Conclusions: Analyzing persistent multivariate brain structural alterations after weight-restoration might help to develop personalized interventions after discharge from inpatient treatment. [ABSTRACT FROM AUTHOR]

Objective: The integration of sensory, motor, and cognitive systems is embodied cognition, according to which mind and body are not separate and distinct, and our body (and our brain, as part of the body) contributes to determining our mental and cognitive processes. In spite of limited data available, Anorexia nervosa (AN) appears as a condition in which embodied cognition is altered, in particular, if we consider bodily sensations and visuospatial information processing. We aimed to evaluate the ability to correctly identify body parts and actions in both full (AN) and atypical AN (AAN), looking at the role of the underweight status. Method: A group of 143 females (AN = 45, AAN = 43, unaffected women = 55) was enrolled. All participants performed a linguistic embodied task to evaluate the association between a picture—showing a bodily action—and a written verb. Additionally, a subsample of 24 AN participants performed a retest after stable weight recovery. Results: Both AN and AAN demonstrated an abnormal ability to evaluate the picture‐written verb associations, especially if the involved bodily effectors were the same in both stimuli (i.e., pictorial and verbal) and needed a longer response time. Conclusions: Specific embodied cognition linked to body schema seems to be impaired in persons with AN. The longitudinal analysis showed a difference between AN and AAN only in the underweight condition, suggesting the presence of an abnormal linguistic embodiment. More attention should be devoted to embodiment during AN treatment to improve bodily cognition, which might, in turn, diminish body misperception. Highlights: Linguistic approach provides new insights into the theory of embodimentLinguistic embodiment appears altered in patients with anorexia nervosaNo significant differences between typical and atypical anorexia nervosa emergedAfter weight recovery, patients with anorexia nervosa showed improved task abilityAll patients required more time for the embodiment task than controlsDisembodiment does not appear to be linked to the severity of underweight [ABSTRACT FROM AUTHOR]

While there is an increasing prevalence of dieting in the overall population, weight loss (WL) practices could be a risk factor for weight gain (WG) in normal-weight (NW) individuals. The aim of the present work was to systematically review all the studies implicating diet restriction and body weight (BW) evolution in NW people. The literature search was registered in PROSPERO (CRD42021281442) and was performed in three databases from April 2021 to June 2022 for articles involving healthy NW adults. From a total of 1487 records initially identified, eighteen were selected in the systematic review. Of the eight dieting interventional studies, only one found a higher BW after weight recovery, but 75 % of them highlighted metabolic adaptations in response to WL favouring weight regain and persisting during/after BW recovery. Eight of the ten observational studies showed a relationship between dieting and major later WG, while the meta-analysis of observational studies results indicated that 'dieters' have a higher BW than 'non-dieters'. However, considering the high methodological heterogeneity and the publication bias of the studies, this result should be taken with caution. Moreover, the term 'diet' was poorly described, and we observed a large heterogeneity of the methods used to assess dieting status. Present results suggest that dieting could be a major risk factor for WG in the long term in NW individuals. There is, however, a real need for prospective randomised controlled studies, specifically assessing the relationship between WL induced by diet and subsequent weight in this population. [ABSTRACT FROM AUTHOR]

Background: A proper diet plan is one of the necessary conditions for maintaining the children's health. The aim of this study was to evaluate the effect of consumption of pasteurized cow's milk fortified with albumin protein in primary-school children, in Yasuj, Iran. Materials and Methods: In this double-blind randomized clinical trial with 12 weeks of duration, 60 children aged 7-13 years, mild to moderate underweight (-1≥ weight-for-age z-score ≥-3), were randomly assigned to control and albumin groups. The albumin group and the control group received 200 cc of milk with 10 g of albumin powder and 200 cc of milk with 10 g of cornstarch powder, respectively. At the beginning and end of the study, food intake and anthropometric indices were measured. Results: After 12 weeks of intervention, none of the anthropometric indices (weight, weight-for-age z-score, body mass index (BMI), BMI-for-age z-score, and waist circumference) showed significant changes as compared to baseline in the control group, but weight-for-age z-score and BMI-for-age z-score showed significant increase as compared to baseline in the albumin group (before: -2.25 ± 0.40, after: -1.98 ± 0.35, P = 0.001 and before: -3.48 ± 0.86, after: -3.06 ± 0.71, P = 0.009, respectively). The comparison of the mean changes between the two groups showed significant difference regarding weight-for-age z-score (control group: -1.70 ± 0.31 in comparison with albumin group: -1.98 ± 0.35, P = 0.002), BMI (control group: 12.08 ± 1.96 in comparison with albumin group: 12.13 ± 1.49, P = 0.03), and BMI-for-age z-score (control group: -3.11 ± 0.91 in comparison with albumin group: -3.06 ± 0.71, P = 0.02). Conclusion: The consumption of albumin powder with milk can improve weight-for-age z-score and BMI-for-age z-score indices in children with mild-to-moderate underweight. Larger controlled interventional studies with longer duration are recommended. [ABSTRACT FROM AUTHOR]

Nutritional status is an important aspect of childhood cancer, with a bearing on the disease and subsequent survivorship. We sought to evaluate the long-term anthropometric outcomes in a cohort of pediatric solid tumor survivors treated between 1994 and 2016. Anthropometry was noted at the time of presentation, after completion of therapy, and at the last follow-up. The z-scores for weight-for-age, height-for-age, and BMI-for-age were calculated using WHO growth charts for ages <5 years and the Indian Academy of Pediatrics growth charts for age >/= 5 years. BMI was calculated for adult survivors. We included 317 survivors, comprising 48, 81, and 188 survivors of Hepatoblastoma (HB), Malignant Germ cell Tumor (MGCT), and Wilms Tumor (WT) respectively. The median age at diagnosis was 24.5 (IQR 59-13.2) months, with a follow-up ranging from 5 to 19.54 years. The z-scores of the collective cohort and individual cohorts of HB, MGCT, and WT showed an improving trend from diagnosis to the last follow-up. The difference in the prevalence of malnutrition was found to be statistically significant when any two-time points were compared. Of the 28 adult survivors, 43% were noted to be underweight. Thus, anthropometric measures improve during follow-up, however, up to 15% of children persist in being malnourished. [ABSTRACT FROM AUTHOR]

Body weight is under physiological regulation. When body fat mass decreases, a series of responses are triggered to promote weight regain by increasing food intake and decreasing energy expenditure. Analogous, in response to experimental overfeeding, excessive weight gain is counteracted by a reduction in food intake and possibly by an increase in energy expenditure. While low blood leptin and other hormones defend against weight loss, the signals that oppose overfeeding-induced fat mass expansion are still unknown. In this article, we discuss insights gained from overfeeding interventions in humans and intragastric overfeeding studies in rodents. We summarize the knowledge on the relative contributions of energy intake, energy expenditure and energy excretion to the physiological defence against overfeeding-induced weight gain. Furthermore, we explore literature supporting the existence of unidentified endocrine and non-endocrine pathways that defend against weight gain. Finally, we discuss the physiological drivers of constitutional thinness and suggest that overfeeding of individuals with constitutional thinness represents a gateway to understand the physiology of weight gain resistance in humans. Experimental overfeeding, combined with modern multi-omics techniques, has the potential to unveil the long-sought signalling pathways that protect against weight gain. Discovering these mechanisms could give rise to new treatments for obesity. This article is part of a discussion meeting issue 'Causes of obesity: theories, conjectures and evidence (Part I)'. [ABSTRACT FROM AUTHOR]

Introduction: Childhood obesity is a serious concern in the United States, with over one third of the pediatric population classified as obese. Abdominal pain is one of the most common chief complaints among pediatric emergency department (ED) visits. We hypothesized that overweight and obese children being evaluated in the ED for abdominal pain would have higher resource utilization than their normal and underweight peers. Methods: This was a retrospective review of pediatric patients <18 years who presented with abdominal pain to the ED of a tertiary care center from January 1, 2014-September 3, 2020. Patients were excluded if they did not have both a height and weight recorded. We categorized patients as underweight (body mass index [BMI] <5th percentile); normal weight (BMI 5th to <85th percentile), overweight (BMI 85th to <95th percentile); or obese (BMI =95th percentile). Descriptive statistics were used to examine the study population. We used chi-square tests to examine the differences in patient characteristics between normal/underweight patients and overweight/obese patients. The Kruskal-Wallis test was completed for examining differences in the medians. We used multivariable logistic regression to examine visit characteristics associated with overweight/obese patients, including ED interventions, testing, and length of stay (LOS). Results: Of the 184 subjects included in the analysis, nine (4.9%) were underweight, 108 (58.7%) were normal weight, 21 (11.4%) were overweight, and 46 (25.0%) were obese. Patients with a BMI of =85th percentile were older (median 15 vs 13 years, P = 0.01). They were otherwise similar in demographics. There was no significant difference between normal/underweight and overweight/obese subjects in disposition (37% vs 43% discharge, P = 0.38), 72-hour return (7% vs 6%, P = 0.82), ED LOS (median 4.42 vs 3.95 hours, P = 0.195), or inpatient LOS (median 42.0 vs 34.2 hours, P = 0.06). There were no statistically significant differences in total number of ED tests or interventions received by overweight/obese patients compared to normal/underweight patients, and each subject received a median of six tests (interquartile range [IQR] 4-7) and two interventions (IQR 1-3). Conclusion: Among pediatric patients presenting to the ED with abdominal pain, we found that patient characteristics and ED resource utilization (including testing, intervention, disposition, and LOS) did not differ significantly across BMI categories. [ABSTRACT FROM AUTHOR]

Objective: Evidence points towards heightened anxiety and attention biases (AB) towards disorder‐specific (threatening) stimuli in patients with anorexia nervosa (AN). To date, it is unclear how anxiety and AB interact in eating disorders (ED). The present study tests the causal role of anxiety by inducing anxiety before a dot‐probe task with either ED‐specific stimuli or unspecific negative (threat‐related) information. We expected that anxiety would elicit AB for ED‐specific, but not for unspecific threat‐related stimuli. Methods: Adolescents with AN (AN, n = 32) or depression (DEP, n = 27) and healthy controls (HC, n = 29) underwent an anxiety induction or a low anxiety control task before a pictorial dot‐probe task with either under‐/overweight body‐related pictures or non‐disorder‐related threatening pictures (angry faces). BMI, level of ED symptoms, anxiety, stress, and depression were assessed at baseline. Results: The anxiety induction did not affect the observed attention pattern. AN showed an AB towards underweight body pictures compared to HC, whereas no disorder‐unspecific threat‐related AB emerged. Regression analyses revealed that only anxiety predicted the AB towards underweight body pictures. Discussion: Further experimental research may integrate eye tracking as an additional tool, or collect information on body dissatisfaction to obtain a better understanding of how anxiety biases attention. Highlights: Patients with AN show attention bias towards underweight body picturesAnxiety manipulation did not affect attention biasState anxiety predicted the strength of biased attention towards underweight body pictures [ABSTRACT FROM AUTHOR]

The identification of somatic growth, through reference curves, can be used to create strategies and public policies to reduce public health problems such as malnutrition and obesity and to identify underweight, overweight and obesity. The purpose of this systematic review was to identify studies providing reference growth curves for weight status in children and adolescents. A systematic search was conducted in eight databases and in gray literature (Google scholar). To assess the risk of bias/methodological quality of studies, the National Institutes of Health (NIH) Quality Assessment Tool for Observational Cohort and Cross-sectional Studies (NHLBI) was used. Overall, 86 studies that met the inclusion criteria were included. Through the values   of reference growth curves for the identification of underweight, overweight and obesity, it was possible to verify that there is great variability among percentiles for the identification of underweight, overweight and obesity. The most prevalent percentiles for underweight were P3 and P5; for overweight, the most prevalent was P85 and the most prevalent percentiles for obesity were P95 and P97. The most prevalent anthropometric indicators were Body Mass Index (BMI), Waist Circumference (WC), Body Mass (BM) for age and height for age. Conclusion: Such data can demonstrate that the optimal growth must be reached, through the standard growth curves, but that the reference curves demonstrate a cut of the population growth, raising possible variables that can influence the optimal growth, such as an increase in the practice of physical activities and an awareness of proper nutrition. [ABSTRACT FROM AUTHOR]

Systematic research on the role of social affirmation from one's religious community on body evaluations is absent. This study therefore explored the relationships among feeling affirmed-from-church, weight-rejection sensitivity, and body evaluations. Drawing from self-affirmation theory, we tested whether a social aspect of religiosity (i.e., feeling affirmed from one's religious community) attenuated the relationship between weight-rejection anxiety and body dissatisfaction, controlling for body mass, affect, and church attendance. We also examined gender differences in religiosity, body image, and fat talk in secular and religious circles in a sample of young adults in the USA (187F, 84M; Mage = 18.59, SD = 0.83). As predicted, both men and women reported hearing less fat-talk at church than among friends, and women reported a positive relation between feeling affirmed-from-church and hearing body-acceptance talk at church. The moderation prediction was supported for women. Greater affirmation-from-church weakened the effect of women's weight sensitivity on body satisfaction (but not weight esteem). For men, affirmation-from-church strengthened the effect of their weight sensitivity on body dissatisfaction and low weight esteem. Feeling affirmed from church may facilitate women's body satisfaction despite their weight-sensitivities. Theoretical and practical implications are discussed. [ABSTRACT FROM AUTHOR]

Purpose: This study investigated the associations of awareness of blood pressure or blood sugar levels and subjective body weight perception with weight loss attempts in overweight and obese adults. Methods: For this cross-sectional, descriptive, survey-based study, data were obtained from the 2021 Community Health Survey conducted by the Korea Disease Control and Prevention Agency. The participants (N=6,571) were adult residents (≥19 years old) of northern Gyeonggi Province in Korea with body mass indexes of 23 kg/m2 or greater. Results: The average age of the participants was 53.11±16.56 years, with a range of 19 to 100 years. Among the participants, 73.2% responded that they had tried to maintain or lose weight in the past year. The prevalence of weight loss attempts was higher among participants with certain demographic characteristics-women (who comprised 39.2% of the study sample), younger individuals, and those with higher education levels-than among their counterparts. Conclusion: Participants who were aware of their blood pressure or blood sugar levels and those with a perception of normal or obese body weight were more likely to attempt weight control than participants without these characteristics. Therefore, encouraging individuals to become aware of their blood pressure or blood sugar levels and to maintain an accurate perception of body weight may motivate them to attempt weight management. [ABSTRACT FROM AUTHOR]

Previous studies have identified popularity as a risk factor for adolescents' body image concerns and disordered eating behaviors, yet little is known about how adolescents' insecure feelings about their popularity status may be associated with these outcomes. To address this gap, this study examined whether popularity status insecurity was linked to weight-related cognitions and behaviors one year later and whether these links were mediated by body dissatisfaction and moderated by popularity status. A total of 233 Chinese 10th and 11th grade adolescents (41% girls; Mage = 15.81 years, SD = 0.68) participated in the study. The results showed that adolescents' popularity status insecurity was positively and indirectly related to greater future drive for thinness and restrained eating through the mediation of dissatisfied feelings about their own body shape only among those with average and low popularity, and these indirect effects were strengthened as adolescents' popularity decreased. Implications for prevention and intervention of eating disturbances for adolescents are discussed. [ABSTRACT FROM AUTHOR]

Introduction: Haemophilia A (HA) is a rare bleeding disorder. Patients with severe HA have a factor VIII activity of < 1%. The clinical picture of severe HA consists of a propensity for spontaneous haemorrhages to the skin, muscles, joints, and internal organs. To prevent severe complications of bleeds, patients with severe HA receive prophylaxis with deficient clotting factor. Obese people have larger absolute fat free mass (FFM) as well as fat mass than non-obese individuals of the same age, gender and height. Factor VIII (FVIII) concentrates are typically confined to the vascular space. Although the pharmacokinetics (PK) based FVIII dosing is becoming a standard in tailoring the prophylaxis for HA patients, the majority of them are still dosed according to total body weight and this may result in an overdose of FVIII. This study aimed to evaluate the PK of FVIII considering patients' body weight and body composition using electrical bioimpedance. Material and methods: Twenty-one boys with severe HA undergoing plasma-derived factor VIII prophylaxis were enrolled in the study. Patients underwent physical examination, body weight and height measurements, had body composition assessed using electrical bioimpedance, FVIII concentration was measured before and 30 min after FVIII administration, and FVIII recovery was evaluated. Patients completed a questionnaire regarding treatment, physical activity, and bleeding. Results: Of the patients who underwent the study, 47.6% had a normal body mass index (BMI), 42.8% were overweight, and 9.5% of patients were underweight. There was a correlation between patients' BMI and FVIII recovery, FFM and FVIII recovery, and fat mass and FVIII recovery. No relationship was found between FVIII recovery and bleeding rate. Conclusions: Determining factor VIII dosage according to FFM requires further study. [ABSTRACT FROM AUTHOR]

Background: Food label is any printed panel on a package or a container of food or food product that contains information of the nutritional value and ingredients of the product. Reading food label during food purchasing would encourage consumers to make healthier choices. This study aimed to explore the association between reading food labels and sociodemographic characteristics, antroprometry assessments, and body weight perception among students aged between 13 and 17 in Malaysia Material and methods : We analysed the data from the Adolescent Nutrition Survey 2017. A two-stage stratified cluster sampling design was used, and a total of 212 schools across Malaysia were selected for this survey. Weighting and the sample design were accounted for in all the analyses. The information read and understanding of food label was collected using a validated self-administered questionnaire. Results : The overall prevalence of reading food labels among students aged 13 to 17 in Malaysia was 84.5%. Girls were found to have significantly higher odds of reading food labels compared to boys (aOR 1.48, p<0.001). Indian, Malay, and others ethnicity of adolescents were reported significantly higher odds of reading food label. The student who answers correct interpretation related to nutrition labeling such as percentage of calories, highest and lowest ingredients also more likely to read the food label. Those with the perception of being overweight and obese were found to have lower odds to read food labels compared to those perceived themselves with normal weight. Students who were currently trying to reduce and increase weight were significantly more likely to read food labels. Conclusion: The prevalence of reading food labels among adolescents in Malaysia is high. However, understanding details related to nutrition labelling should be a part of all programs directed towards tackling the benefit of reading food labels while during food selection. [ABSTRACT FROM AUTHOR]

Aim: The study aimed to determine trends in the prevalence of underweight, overweight, obesity and their putative risk factors in different cohorts from a representative population of adolescents in Central Italy. Subject and methods: After random sampling, five cohorts of adolescents attending public high schools – aged 14 to 18 years – were evaluated from 2005 to 2018 (n: 25,174). Collected information included self-reported body mass index (BMI), descriptors of family environment, eating behaviour, physical activity, screen use, bullying victimisation, sexual behaviour (age at first intercourse, number of partners) and perceived psychological distress. For these data, between-cohort prevalence differences were used to esteem prevalence variations across time. In the 2018 cohort, the association between these factors and body weight was evaluated through multinomial regressions with sex-specific crude relative risk ratios for different BMI categories. Results: An increased prevalence of overweight was observed for both boys and girls. The study outlined a transition towards higher parental education and unemployment, reduced soft drinks consumption and higher psychological distress. Sex-specific changes were observed for physical and sexual activity, and a rising percentage of girls reported being bullied and distressing family relationships. Parental education and employment, together with physical activity, confirmed to be protective factors against pathological weight. The latter clustered with reduced soft drinks consumption, bullying victimisation, early sexual activity, worse family relationships and higher distress. Conclusion: An increased prevalence of both overweight and underweight was observed across time. Economic factors associated with unemployment and changes in behavioural patterns may have contributed to this trend. [ABSTRACT FROM AUTHOR]

Background: Assisted falls occur when staff try to minimize the impact of falls by slowing a patient's descent. Assisting a patient fall may decrease patient injury risk, but biomechanical risk of injury to staff has not been evaluated. Assisted falls virtual reality (VR) simulations were conducted to examine staff low back injury risk during common assisted falls scenarios. Methods: VR simulations of a toilet to wheelchair transfer were developed with a male patient avatar for three assisted falls scenarios: standing up from toilet, sitting down on wheelchair, and ambulation. Patient avatar weight was modified to reflect normal, underweight, and overweight adult patients. The average spinal compression force at L5/S1 was calculated for each participant with five trials per three scenarios while utilizing physical ergonomic techniques and compared to the safe spinal compression limit of 3,400 Newtons (N). Findings: Six staff participants completed 90 VR simulations in total. The average calculated spinal compression force ranged from 7,132 N to 27,901 N. All participant trials exceeded the safe spinal compression limit of 3,400 N for every assisted falls scenario and avatar weight despite application of ergonomic techniques including wide stance, knees bent, and backs straight. Conclusions/Application to Practice: Staff are at risk for low back injury if they assist falls regardless of the adult patient weight and application of ergonomic techniques. Safer alternatives like the implementation of mobility screening tools and safe patient handling and mobility technology are needed to help prevent assisted falls to decrease injury risk to both patients and staff. [ABSTRACT FROM AUTHOR]

The role of adolescent weight status in psychosocial, cognitive, and academic outcomes remains understudied, particularly among girls in low- and middle-income countries. This study examined the direct and indirect effects of weight status, self-efficacy, and gender attitudes on cognitive and academic skills among adolescent girls. We analyzed two rounds of data collected from adolescent girls (N = 4,693) who participated in the Adolescent Girls Empowerment Program in Zambia. Weight status, self-efficacy, and gender attitudes were measured in 2014–2015. Cognitive and academic skills were measured, 1 year later. Analyses were conducted using confirmatory factor analysis and structural equation modeling. Being underweight was significantly associated with lower self-efficacy, and cognitive and academic skills. Self-efficacy and gender attitudes were significantly associated with cognitive and academic skills. Self-efficacy mediated the association of being underweight with cognitive and academic skills. Our results found no significant association of normal weight with cognitive and academic abilities. Undernutrition, low self-efficacy, and weak cognitive and academic abilities during adolescence illustrate the intersecting vulnerabilities faced by adolescent girls. Study findings suggest multiple pathways to improve adolescent girls' weight status and cognitive and academic skills. [ABSTRACT FROM AUTHOR]

Purpose: To systematically assess the main sociodemographic factors associated with weight perception of adolescents. Methodology: All studies related to adolescents' weight perception were retrieved from seven databases from January 2001 to July 2022. A total of 13 Medical Subject Headings (MeSH) and keywords were used to identify qualified studies, and reference lists included in the retrieved studies were manually searched to identify potentially relevant publications. Two evaluators independently assessed the eligibility and extracted data of each study. Agency for Healthcare Research and Quality (AHRQ) risk of bias evaluation tool was used to evaluate the quality and bias risk of included studies. RevMan (version: 5.3) software was used to conduct heterogeneity test and meta‐analysis. Results: A total of 12 studies, published between 2003 and 2020, were selected and included in the systematic review and meta‐analysis, consisting of 325,367 adolescents from five countries. The risk of bias evaluation indicated that risk of bias was low in five studies and moderate in seven studies. The results of meta‐analysis showed that there were no differences in the weight perception accuracy among adolescents under different gender (odds ratio [OR] = 1.00, 95% confidence interval [CI]: 0.88–1.15, p = 0.940), place of residence (OR = 0.98, 95% CI: 0.83–1.16, p = 0.800), grade (OR = 1.73, 95% CI: 0.68–4.42, p = 0.250), and family economic level (OR = 0.94, 95% CI: 0.86–1.02, p = 0.140). Egger's linear regression showed that there was no significant publication bias in the primary analysis. Conclusions: The current analysis indicates that gender, place of residence, grade, and family economic level were not identified as influencing factors for adolescents' weight perception accuracy. Due to the limitations of the review and included studies, more robust trials are warranted in different social and economic environments to confirm our findings. [ABSTRACT FROM AUTHOR]

Background. Among lifestyle factors, obesity has been postulated as the most important risk factor for metabolic syndrome (MS). Lifestyle factors such as physical activity (PA), diet quality, and weight management are so closely related, it is not clear if the role of lifestyle factors is exclusively through its effect on weight, or if they contribute independently. Objective. To examine the effect of lifestyle factors such as diet quality, weight change, and leisure time PA on MS occurrence in lean and overweight/obese (OW/OB) adults over a 6-year period. Methods. This was a longitudinal analysis of data from adults participating in the Health Workers Cohort Study. Results. A total of 1046 participants were included; 37.2% of the OW/OB group and 16.2% of the lean participants developed MS. Becoming overweight had a hazard ratio (HR) of 3.06 for developing MS compared with remaining lean (95% CI = 1.98, 4.74). Going from OW/OB to lean was associated with lower risk of MS (HR = 0.41; 95% CI = 0.22, 0.79). Among OW/OB, becoming active was associated with lower risk (HR = 0.63; 95% CI = 0.42, 0.95) in comparison with an inactive pattern; diet quality was not associated with occurrence of MS. Conclusion. Weight change was the most relevant factor predicting MS over a 6-year period. [ABSTRACT FROM AUTHOR]

Context Obesity is a significant risk factor for many pathological conditions. Whether a gluten-free diet (GFD) is a risk factor for overweight or obesity remains controversial. Objective The primary aim of this study was to assess the prevalence of body mass index (BMI) categories at disease presentation and the variation in BMI category from underweight/normal to overweight/obese and vice versa during a GFD. Data Sources PubMed, Scopus, and Web of Science databases were searched through February 2021 for retrospective, cross-sectional, and prospective studies reporting BMI categories at disease diagnosis and during a GFD. Data Extraction Data were extracted by 2 reviewers independently. Disagreements were resolved by consensus; a third reviewer was consulted, if necessary. Risk of bias was assessed with the Cochrane ROBINS-I tool. Data Analysis Subgroup analysis based on age (pediatric/adult patients), study design (prospective, cross-sectional, retrospective), and duration of GFD was performed.. Forty-five studies were selected (7959 patients with celiac disease and 20 524 healthy controls). The mean BMI of celiac patients at presentation was significantly lower than that of controls (P  < 0.001). During a GFD, the mean BMI increased significantly (mean difference = 1.14 kg/m2 [95%CI, 0.68–1.60 kg/m2]; I2  = 82.8%; P  < 0.001), but only 9% of patients (95%CI, 7%–12%; I2  = 80.0%) changed from the underweight/normal BMI category to the overweight/obese category, while 20% (95%CI, 11%–29%; I2  = 85.8%) moved into a lower BMI category. Conclusion Most celiac patients had a normal BMI at presentation, although the mean BMI was significantly lower than that of controls. A GFD does not increase the risk of becoming overweight/obese, especially in children. The quality of several studies was suboptimal, with moderate or high overall risk of bias and heterogeneity. [ABSTRACT FROM AUTHOR]

Muscularity-oriented disordered eating (MODE) refers to a broad cluster of pathological eating patterns driven by the pursuit of muscularity and leanness. Although increasing attention has been devoted towards understanding these symptoms in men, little work has been conducted to understand MODE in women. It is also unclear whether MODE contributes unique variance to functional impairment and emotional distress beyond thinness-oriented disordered eating symptoms. We addressed these gaps in a sample of 1,321 community-based adult women (n = 1136) and men (n = 185). Hierarchical multiple regressions revealed that MODE explained a significant proportion of unique variance in functional impairment in both men and women, even after controlling for traditional thinness-oriented disordered eating symptoms. MODE also contributed unique variance in symptoms of depression and anxiety in women, but not for men. Findings highlight the possible significance of these unique symptoms patterns geared towards the pursuit of muscularity and leanness. MODE symptoms may be a viable target in eating disorder intervention or prevention programs, although further longitudinal research is needed. [ABSTRACT FROM AUTHOR]

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Background: Epidemiological studies have reported that among participants with impaired cognitive, overweight and mild obesity are associated with substantially improved survival, this finding has been termed the "obesity paradox" and has led to uncertainty about secondary prevention. Aims: To explore whether the association of BMI with mortality differed in different MMSE score, and whether the obesity paradox in patient with cognitive impairment (CI) is real. Methods: The study used data from CLHLS, a representative prospective population-based cohort study in China, which included 8348 participants aged ≥ 60 years between 2011 and 2018. The independent association between BMI and mortality in differed MMSE score by calculating hazard ratios (HRs) in multivariate Cox regression analysis. Results: During a median (IQR) follow-up of 41.18 months, a total of 4216 participants died. In the total population, underweight increased the risk of all-cause mortality (HRs, 1.33; 95% CI 1.23–1.44), compared with normal weight, and overweight was associated with a decreased risk of all-cause mortality (HR 0.83; 95% CI 0.74–0.93). However, compared to normal weight, only underweight was associated with increased mortality risk among participants with MMSE scores of 0–23, 24–26, 27–29, and 30, and the fully-adjusted HRs (95% CIs) for mortality were 1.30 (1.18, 1.43), 1.31 (1.07, 1.59), 1.55 (1.34, 1.80) and 1.66 (1.26, 2.20), respectively. The obesity paradox was not found in individuals with CI. Sensitivity analyses carried out had hardly any impact on this result. Conclusion: We found no evidence of an obesity paradox in patients with CI, compared with patients of normal weight. But underweight individuals may have increased mortality risk whether in the population with CI or not. And overweight/obese people with CI should continue to aim for normal weight. [ABSTRACT FROM AUTHOR]

Obesity and undernutrition are manifestations of malnutrition that affect many people worldwide. A lack of access to food may explain the association of food insecurity (FI) with both undernutrition and obesity, but there are other factors that are specifically related to obesity. Studies have also found that FI is related to both overweight and obesity among women but not among men. The present study aimed to evaluate the association between FI and weight status among adults from a nationally representative sample of Brazil and to consider the impacts of sex. Data from the 2017–2018 Household Budget Survey (n 28 112), a national cross-sectional study, were analysed using the Brazilian Household FI Scale (EBIA) and BMI (measured in kg/m2) by individual self-reported weight and height. Associations were estimated by OR with 95 % CI considering a multinomial logistic regression model. Women with severe FI were more than twice (OR = 2·36) as likely to be underweight and had a higher frequency of obesity (OR = 1·39). Among men, severe FI status was a protective factor for overweight (OR = 0·58) and obesity (OR = 0·61). In conclusion, FI was a risk factor for underweight and obesity among women but not among men. [ABSTRACT FROM AUTHOR]

Summary: Background: Evidence for longitudinal associations between childhood weight status and academic achievement remains unclear due to considerable heterogeneity in study design, measures of academic achievement and appropriate categorization of weight status. Objective: To examine longitudinal associations between childhood weight status (underweight, healthy weight, overweight/obese) and academic achievement in the transition from preschool to primary (elementary) school among Australian school children. Methods: Data were from the Healthy Active Preschool and Primary Years study. Height and weight, for calculating BMI were measured at baseline (preschool age 3–5 years; 2008/9) and follow‐up (primary school age 6–8 years; 2011/12). Academic achievement was measured at age 9 years. Results: No associations between BMI z‐score or weight category in the preschool years and later NAPLAN scores were found for boys. For girls, having a higher BMI z‐score (B = −13.68, 95%CI: −26.61, −0.76) and being affected by overweight (B = −33.57, 95%CI: −61.50, −5.24) in preschool was associated with lower language scores. Remaining affected by overweight from preschool to primary school was associated with lower numeracy (B = −25.03, 95%CI: −49.74, −0.33), spelling (B = −33.5, 95%CI: −63.43, −3.58), language (B = −37.89, 95%CI: −72.75, −3.03) and total achievement scores (B = −24.24, 95%CI: −44.85, −3.63) among girls. For boys, becoming affected by overweight was associated with lower spelling (B = −38.76, 95%CI: −73.59, −3.93) and total achievement scores (B = −27.70, 95%CI: −54.81, −0.58). Conclusions: Associations between being affected by overweight/obesity and poorer academic achievement were more pronounced in girls than boys, indicating potentially inequitable impacts of excess weight and highlighting the greater need for intervention among girls. However, stronger study designs are needed to confirm our findings. [ABSTRACT FROM AUTHOR]

Copyright of QhaliKay: Revista de Ciencias de la Salud is the property of QhaliKay Revista de Ciencias de la Salud and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)