1. Effects of nonsynonymous single nucleotide polymorphisms of the KIAA1217, SNTA1 and LTBP1 genes on the growth traits of Ujumqin sheep.
- Author
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Zhichen Liu, Qing Qin, Chongyan Zhang, Xiaolong Xu, Dongliang Dai, Mingxi Lan, Yichuan Wang, Jingwen Zhang, Dan Zhao, Deqing Kong, Tian Qin, Danni Wu, Xuedan Gong, Xingyu Zhou, Suhe, Alatan, Zhixin Wang, and Zhihong Liu
- Subjects
SINGLE nucleotide polymorphisms ,SHEEP breeds ,SHEEP ,SHEEP breeding ,WHEAT breeding ,GOAT milk ,BODY size - Abstract
Sheep body size can directly reflect the growth rates and fattening rates of sheep and is also an important index for measuring the growth performance of meat sheep. In this study, high-resolution resequencing data from four sheep breeds (Dorper sheep, Suffolk sheep, Ouessant sheep, and Shetland sheep) were analyzed. The nonsynonymous single nucleotide polymorphisms of three candidate genes (KIAA1217, SNTA1, and LTBP1) were also genotyped in 642 healthy Ujumqin sheep using MALDI-TOFMS and the genotyping results were associated with growth traits. The results showed that different genotypes of the KIAA1217 g.24429511T>C locus had significant effects on the chest circumferences of Ujumqin sheep. The SNTA1 g.62222626C>A locus had different effects on the chest depths, shoulder widths and rump widths of Ujumqin sheep. This study showed that these two sites can be used for marker-assisted selection, which will be beneficial for future precision molecular breeding. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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