1. A novel cell death gene acts to repair patterning defects in Drosophila melanogaster.
- Author
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Tanaka KM, Takahashi A, Fuse N, and Takano-Shimizu-Kouno T
- Subjects
- Animals, Cell Death genetics, Drosophila Proteins genetics, Drosophila melanogaster genetics, Gene Knockdown Techniques, Head embryology, Body Patterning genetics, Drosophila Proteins metabolism, Drosophila melanogaster embryology, Gene Expression Regulation, Developmental
- Abstract
Cell death is a mechanism utilized by organisms to eliminate excess cells during development. Here, we describe a novel regulator of caspase-independent cell death, Mabiki (Mabi), that is involved in the repair of the head patterning defects caused by extra copies of bicoid in Drosophila melanogaster. Mabiki functions together with caspase-dependent cell death mechanisms to provide robustness during development., (Copyright © 2014 by the Genetics Society of America.)
- Published
- 2014
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