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Background and objective: Gastroesophageal reflux disease (GERD) is a digestive complication that is common in adults and defined by heartburn and regurgitation. Due to the increasing frequency and problems of the disease, epidemiological features of GERD have been considered in recent years. Therefore, we examined the factors related to GERD in different body mass index (BMI) categories. Materials and methods: We did a cross-sectional analysis of the primary information from a populationbased cohort study of 10520 people in Guilan Province, Iran. Demographic characteristics such as age, gender, smoking history, and alcohol consumption were collected using a self-administered questionnaire; also, anthropometric and clinical information were surveyed. Data analyzed with SPSS version 21.0. Results and conclusion: A total of 10520 participants were aged 35 to 70 years and included 5633 (53.55%) females and 4887 (46.45%) males. The frequency of GERD was 13.2% in the present study and was more prevalent in people with high BMI levels. According to analysis, GERD was significantly associated with female gender and low physical activity. Alcohol and smoke use was inversely associated with GERD. This large population-based study indicated risk factors in people with high BMI increased occurrence of GERD that altering these variables may reduce or prevent GERD indications must be elucidated in controlled trials. [ABSTRACT FROM AUTHOR]

Background and objective: The development of health indexes in recent years drag more attention to everyday life style and the impacts of socioeconomic status (SES) on individual's health state. In this regard, we aimed to investigate the socioeconomic status (SES) among the PERSIAN Guilan cohort population by considering the prevalence of gastroesophageal reflux disease (GERD) in these participants. Materials and methods: This cross-sectional study was conducted based on the PERSIAN cohort study from October 2014 to January 2017 on 10520 individuals. Data including age, gender, body mass index (BMI), educational level, habitat, and SES of patients were collected from all individuals and analyzed using SPSS.16 with a significant level <0.05. Results and conclusion: The results illustrated that out of 10520 participants, 1385 patients had GERD that its distribution was 34.9%, 33.6%, and 31.6% in low, moderate, and high levels of SES, respectively. Due to results, age, gender, educational status, and habitat significantly associated with GERD according to three levels of SES (P<0.05). GERD was more frequent in patients with low, moderate, and high levels of SES, respectively. Age, gender, educational status, and habitat, represented a significant association with different levels of SES among patients with GERD (P<0.05). This large population-based study indicated the increased risk of GERD in the low SES group compare to middle and high-SES groups, which highlighted the role of SES in the health status of individuals. [ABSTRACT FROM AUTHOR]