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Your search keyword '"Lipids"' showing total 2 results
2 results on '"Lipids"'

1. A workplace-based risk assessment improves predicted lifetime cardiovascular disease risk in male steelworkers.

Author

Gray, B. J., Bracken, R. M., Turner, D., Long, S. J., Thomas, M., Williams, S. P., Davies, C. A., Morgan, K., Williams, M., Rice, S., and Stephens, J. W.

Subjects
*BLOOD pressure, *CARDIOVASCULAR diseases, *EMPLOYEES, *LIPIDS, *LONGITUDINAL method, *OPERATING room personnel, *RISK assessment, *SHIFT systems, *WORK environment, *BODY mass index, *DESCRIPTIVE statistics
Abstract

The article discusses a study that discusses the role of a workplace-based risk assessment in improving a lifetime cardiovascular disease risk in male steelworkers in Great Britain. It informs that the study included a sample of male employees from a local steelworks in Carmarthenshire, South Wales, and undergone cardiovascular disease (CVD) and diabetes risk assessment and the results showed that workplace-based CVD initiatives were beneficial to shift workers.

Published
2016
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2. Apolipoprotein E genotype and the cardiovascular disease risk phenotype: Impact of sex and adiposity (the FINGEN study)

Author

Kofler, Bettina M., Miles, Elizabeth A., Curtis, Peter, Armah, Christopher K., Tricon, Sabine, Grew, Jilly, Napper, Frances L., Farrell, Leslie, Lietz, Georg, Packard, Christopher J., Caslake, Muriel J., Mathers, John C., Williams, Christine M., Calder, Philip C., and Minihane, Anne Marie

Subjects
*APOLIPOPROTEIN E gene, *PHENOTYPES, *OBESITY, *CARDIOVASCULAR diseases, *LOW density lipoproteins, *BODY mass index
Abstract

Abstract: Here the impact of APOE genotype on CHD risk in UK adults is reported, along with an analysis of APOE genotype×BMI/age/sex interactions. APOE genotype had a significant impact on fasting total:LDL-cholesterol (TC:LDL-C) ratio, triglycerides, % HDL3, and the Framingham 10-year CVD risk score (P <0.05), with an overall trend towards lower and higher risk in E2- and E4-carriers, respectively, relative to the wild-type E3/E3 genotype. A greater impact of genotype on TC:HDL-C was observed in females, which explained 16% of the variability in this outcome versus 6% in males. APOE genotype was also associated with plasma C-reactive protein and adhesion molecule concentrations (P <0.05), with significant genotype×BMI interactions observed. Our observations indicate that the association between the APOE genotype and CHD risk is unlikely to be homogenous and highlights the risk of inaccurate estimations of genotype–phenotype associations in population subgroups without appropriate stratification for sex and adiposity. [Copyright &y& Elsevier]

Published
2012
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