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1. Secukinumab distributes into dermal interstitial fluid of psoriasis patients as demonstrated by open flow microperfusion.

Author

Dragatin C, Polus F, Bodenlenz M, Calonder C, Aigner B, Tiffner KI, Mader JK, Ratzer M, Woessner R, Pieber TR, Cheng Y, Loesche C, Sinner F, and Bruin G

Subjects
Antibodies, Monoclonal administration & dosage, Antibodies, Monoclonal immunology, Antibodies, Monoclonal, Humanized, Body Weight, Drug Evaluation, Preclinical, Humans, Injections, Subcutaneous, Interleukin-17 immunology, Perfusion, Time Factors, Antibodies, Monoclonal pharmacokinetics, Body Fluids metabolism, Psoriasis metabolism
Published
2016
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