1. Synthesis and properties of a series of carboranyl-BODIPYs.
- Author
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Gibbs, Jaime H., Wang, Haijun, Bhupathiraju, N.V.S. Dinesh K., Fronczek, Frank R., Smith, Kevin M., and Vicente, M. Graça H.
- Subjects
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CARBORANES , *CHEMICAL synthesis , *METAL clusters , *PALLADIUM catalysts , *SUZUKI reaction , *NUCLEOPHILIC substitution reactions - Abstract
A series of four BODIPYs containing one or two ortho - or para -carborane clusters were synthesized using palladium(0)-catalyzed Suzuki cross-coupling or nucleophilic substitution reactions, at the 2,6- or the 8-positions of halogenated boron dipyrromethenes (BODIPYs). The spectroscopic, structural (including one X-ray) and in vitro BBB permeability of the BODIPYs using hCMEC/D3 brain endothelial cells were investigated. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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