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This Letter presents the implementation in a hardware device of the mean arterial pressure (MAP) response model of patients subjected to the infusion of the vasoconstrictor drug phenylephrine, enabling the development of automatic control systems in the future. The proposed model was firstly developed in a software platform with Simulink/MatLab using block libraries based on previous research carried out with animals and then implemented on hardware using a single-board computer with microcontroller and code generated in C/C++. The responses of MAP were simulated and compared using the proposed software and hardware model, considering the dynamic effects of several patients. The results showed that the hardware model presented 0.43% as the largest absolute percentage error observed in all trials, for an injection rate of the drug varying in steps with levels of 40 ml/h [ABSTRACT FROM AUTHOR]

The lack of models for automatic control of mean arterial pressure (MAP), in real‐time, associated with variability in response to sodium nitroprusside infusion, makes it impossible to validate automatic MAP controllers. Therefore, this Letter presents a low‐cost innovative real‐time model to MAP. Therefore, the authors used a variation of the mathematical model of Slate, implemented in MATLAB®. The system was developed with the capabilities of Simulink® and deployed to a single‐board computer. The results showed that the embedded model presented an error <3% for a target MAP of 100 mmHg, allowing the use of this model, in real time, for validation of embedded MAP controllers. [ABSTRACT FROM AUTHOR]