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Your search keyword '"Gamaldo, Alyssa A."' showing total 3 results
Start Over Author "Gamaldo, Alyssa A." Topic blood pressure Topic cognition
3 results on '"Gamaldo, Alyssa A."'

1. Exploring the within-person coupling of blood pressure and cognition in elders.

Author

Gamaldo AA, Weatherbee SR, and Allaire JC

Subjects
Aged, Aged, 80 and over, Blood Pressure Determination, Female, Humans, Longitudinal Studies, Male, Michigan, Middle Aged, Multivariate Analysis, Regression Analysis, Blood Pressure, Cognition
Abstract

In this study, we examined the relationship between within-person blood pressure and cognitive functioning. We conducted an analysis on 36 community-dwelling elderly individuals (age range = 60-87 years). Participants measured their blood pressure and completed cognitive tasks (i.e., the Rey Auditory Verbal Learning Task, the Letter Series test, and the Number Comparison test) twice a day over 60 consecutive days. We observed a significant interaction between within-person change in blood pressure and average blood pressure for the Letter Series test. Individuals with high blood pressure tended to perform poorly, particularly on occasions when their blood pressure level was above their personal average. These results demonstrate that the relationship between blood pressure and cognition at the between-person level and the relationship within each individual should be further explored simultaneously.

Published
2008
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2. Cognition and Health in African American Men.

Author

Sims, Regina C., Thorpe, Roland J., Gamaldo, Alyssa A., Aiken-Morgan, Adrienne T., Hill, LaBarron K., Allaire, Jason C., and Whitfield, Keith E.

Subjects
BLACK people, BLOOD pressure, CARDIOVASCULAR diseases, COGNITION, EDUCATION, HEALTH status indicators, PROBABILITY theory, PSYCHOLOGICAL tests, REGRESSION analysis, PULMONARY function tests, SMOKING, SECONDARY analysis, DATA analysis software
Published
2015
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3. The Association of Stress, Metabolic Syndrome, and Systemic Inflammation With Neurocognitive Function in the Hispanic Community Health Study/Study of Latinos and Its Sociocultural Ancillary Study

Author

Linda C. Gallo, Alison A. Moore, Carmen R. Isasi, Benson Wu, María J. Marquine, Sherman J Bigornia, Gregory A. Talavera, Matthew A. Allison, Martha L. Daviglus, Hector M. González, Priscilla M. Vásquez, Elizabeth Munoz, Krista M. Perreira, Wassim Tarraf, Mayra L. Estrella, Donglin Zeng, and Gamaldo, Alyssa

Subjects
Male, Aging, Waist, Social Psychology, Clinical Sciences, Disease, Systemic inflammation, Basic Behavioral and Social Science, Cognition, Sociology, Risk Factors, Behavioral and Social Science, 2.1 Biological and endogenous factors, Psychology, Humans, Medicine, Stress measures, Minority and diverse populations, Aetiology, Inflammation, Metabolic Syndrome, business.industry, Stressor, Neurosciences, Hispanic or Latino, Cardiovascular disease, medicine.disease, Clinical Psychology, Mental Health, Good Health and Well Being, THE JOURNAL OF GERONTOLOGY: Psychological Sciences, C-Reactive Protein, Cross-Sectional Studies, Blood pressure, Female, Self Report, Geriatrics and Gerontology, medicine.symptom, Metabolic syndrome, business, Gerontology, Neurocognitive, Clinical psychology
Abstract

Objectives Identifying sociocultural correlates of neurocognitive dysfunction among Hispanics/Latinos, and their underlying biological pathways, is crucial for understanding disparities in Alzheimer’s disease and related dementias. We examined cross-sectional associations between stress and neurocognition, and the role that metabolic syndrome (MetS) and systemic inflammation might play in these associations. Method Participants included 3,045 adults aged 45–75 (56% female, education 0–20+ years, 86% Spanish-speaking, 23% U.S.-born), enrolled in the Hispanic Community Health Study/Study of Latinos and its Sociocultural Ancillary Study. Global neurocognition was the primary outcome and operationalized as the average of the z scores of measures of learning and memory, word fluency, and processing speed. Stress measures included self-report assessments of stress appraisal (perceived and acculturative stress) and exposure to chronic and traumatic stressors. MetS was defined via established criteria including waist circumference, high blood pressure, elevated triglycerides, fasting plasma glucose, and high levels of high-density lipoprotein cholesterol. Systemic inflammation was represented by high-sensitivity C-reactive protein (hs-CRP). Results Separate survey multivariable linear regression models adjusting for covariates showed that higher perceived (b = −0.004, SE = 0.002, p < .05) and acculturative stress (b = −0.004, SE = 0.001, p < .0001) were significantly associated with worse global neurocognition, while lifetime exposure to traumatic stressors was associated with better global neurocognition (b = 0.034, SE = 0.009, p < .001). Neither MetS nor hs-CRP were notable pathways in the association between stress and neurocognition; rather, they were both independently associated with worse neurocognition in models including stress measures (ps < .05). Discussion These cross-sectional analyses suggest that stress appraisal, MetS, and systemic inflammation may be targets to reduce neurocognitive dysfunction among Hispanics/Latinos.

Published
2021

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