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Objective: To retrospectively evaluate the distribution of ABO and RhD blood groups and their relationship with diseases. Methods: The retrospective study was carried out in Bursa Uludag University Family Health Center in Turkey between 1-28 February, 2023. The data of individuals who were registered with the Family Health Center and whose blood types were known were evaluated retrospectively. Blood group type, sociodemographic findings, existing diseases, allergies, and genetic disease conditions were obtained. P-values below 0.05 were considered statistically significant. Analysis were made in the SPSS 25.0 program. Results: A total of 3834 people, 1935 male (50.5%) and 1899 female (49.5%) participated in the study. The mean age of the individuals was 26.45±10.45 years. About 75.8 percent of the participants were university students, 6.3 percent were health workers, and 17.9 percent were from other occupational groups. The rates of blood groups were determined as O Rh D+ at 33.5%, AB Rh D+ at 26.9%, A Rh D+ at 14.9%, AB Rh D- at 7.7%, B Rh D+ at 7%, O Rh D- at 4.6%, B Rh D- at 3.2% and A Rh D- at 2.2%. It was determined that the O Rh D- group had a higher rate of genetic disease than the other groups (p=0.01). Conclusion: It was determined that the O Rh D+ blood group was found more frequently in our region's population than in other groups. This different result depending on the A Rh D+ blood group, which is the most common throughout the country may have reflected the influence of different geographical regions and ethnic characteristics due to the students in our population. In addition, the results regarding the relationships between blood groups and occupation, genetics, existing disease, presence of allergies, and visual defects in the eye are important. [ABSTRACT FROM AUTHOR]

Background: Our study aimed to identify preoperative predictors for perioperative allogenic blood transfusion (ABT) in patients undergoing major lung cancer resections in order to improve the perioperative management of patients at risk for ABT. Methods: Patients admitted between 2014 and 2016 in a high-volume thoracic surgery clinic were retrospectively evaluated in a cohort study based on a control group without ABT and the ABT group requiring packed red blood cell units within 15 days postoperatively until discharge. The association of ABT with clinically established parameters (sex, preoperative anemia, liver and coagulation function, blood groups, multilobar resections) was analyzed by contingency tables, receiver operating characteristics (ROC) and logistic regression analysis, taking into account potential covariates. Results: 60 out of 529 patients (11.3%) required ABT. N1 and non-T1 tumors, thoracotomy approach, multilobar resections, thoracic wall resections and Rhesus negativity were more frequent in the ABT group. In multivariable analyses, female sex, preoperative anemia, multilobar resections, as well as serum alanine-aminotransferase levels, thrombocyte counts and Rhesus negativity were identified as independent predictors of ABT, being associated with OR (95% Confidence interval, p-value) of 2.44 (1.23–4.88, p = 0.0112), 18.16 (8.73–37.78, p < 0.0001), 5.79 (2.50–13.38, p < 0.0001), 3.98 (1.73–9.16, p = 0.0012), 2.04 (1.04–4.02, p = 0.0390) and 2.84 (1.23–6.59, p = 0.0150), respectively. Conclusions: In patients undergoing major lung cancer resections, multiple independent risk factors for perioperative ABT apart from preoperative anemia and multilobar resections were identified. Assessment of these predictors might help to identify high risk patients preoperatively and to improve the strategies that reduce perioperative ABT. [ABSTRACT FROM AUTHOR]

Introduction: Various studies have proved the association between several disease including dental crowding, malocclusion and craniofacial deformities with blood group. Certain skeletal problems in sagittal plane are heritable and the skeletal muscle volume and strength, a heritable trait varies with different facial patterns. Aim: To evaluate the association between ABO blood groups and Rhesus (Rh) factor with skeletal malocclusions in sagittal and vertical plane. Materials and Methods: An observational study was conducted with a sample of 240 participants who reported to Department of Orthodontics in SRM dental college and hospital, Chennai, Tamil Nadu, India seeking orthodontic treatment over a period of two years from September 2018 to December 2020. Participants were assessed for skeletal malocclusion in sagittal and vertical plane and for their ABO and Rh blood grouping. Chi square test was used for determining the association between sagittal and vertical skeletal malocclusion with ABO and Rh blood grouping. The association of the gender and the malocclusion was determined as a secondary outcome of the study. Results: A total of 240 participants (mean age: 19.81±5.95 years; 95 males and 145 females) were observed and data was analysed. A significant association was found between Rh positive blood group and skeletal class II malocclusion with high angle (p-value 0.025) Skeletal class I malocclusion with high angle was found to be associated significantly with O+ group (p-value<0.001). The female gender was found to be associated significantly with sagittal skeletal class II malocclusion with high angle (p-value 0.049). Conclusion: There is an association between the ABO blood groups and skeletal sagittal malocclusion and vertical skeletal pattern. Skeletal class II malocclusion with high angle pattern was associated significantly with Rh+ blood group and Class I Skeletal malocclusion with high angle pattern was significantly associated with O+ blood group. [ABSTRACT FROM AUTHOR]

Background: Among the blood group antigens identified, ABO and Rhesus are the most important in transfusion medicine. ABO blood group antigens are the most immunogenic followed by Rhesus (D antigen). These blood groups' frequency distribution varies among different regions and races of the world. This study aimed to identifying the frequency distribution of ABO blood group and rhesus factors among blood donors in Ethiopia. Methods and Materials: Aretrospective cross-sectional study was conducted from September 12/2019 to March 18/2021 at Bahir Dar blood bank service. After getting a permission letter from the blood bank, data were collected from the blood bank donor data registration system, and descriptive statistical results were presented in number (frequency) and percentage. A Chi-square test was used to show the difference in the frequency distribution of ABO and Rh blood groups among sex and blood donation site. Results: From 40,053 blood donors, 67.7% were males and younger donors (within the age range of 18– 24 years) account for 63.7%. All donations were from voluntary non-remunerated blood donors. The most common blood group was blood group O (41.5%) followed by A (29.8), B (23.2%), and AB (5.5%). Considering ABO and Rh blood group altogether blood group O positive with 37.9% was the predominant blood group followed by A positive (27.2%), B positive (21.4%), AB positive (5%), O negative (3.6%), A negative (2.6%), B negative (1.8%), and AB negative (0.4%). The majority of study participants were 91.5% Rh (D) positive. Conclusion: This study showed that blood group O was the predominant followed by A, B, and AB and most of the blood donors' blood groups were Rh-positive (91.5%). About 68.9% of the total donations were from the first time donor. [ABSTRACT FROM AUTHOR]

At the onset of the COVID-19 pandemic, Intermountain prospectively initiated a SARS-CoV-2/COVID-19-specific electronic records database. Keywords: blood type; COVID-19; rhesus factor; risk factor; SARS- CoV-2 EN blood type COVID-19 rhesus factor risk factor SARS- CoV-2 573 575 3 05/31/22 20220601 NES 220601 BACKGROUND Substantial attention has been paid to ABO blood type as a potential risk factor for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) susceptibility and coronavirus disease 2019 (COVID-19) severity, but this association remains controversial.1 Less attention has been paid to whether Rhesus (Rh) factor is associated with COVID-19 risk. Blood type, COVID-19, rhesus factor, risk factor, SARS- CoV-2. [Extracted from the article]

Introduction: Blood is arranged into four groups based on their surface antigen (A, B, AB, and O). In addition to this classification based on the Rhesus factor, each blood group clustered into RH positive and RH negative. This study was done to identify the distribution of blood group and rhesus factors on the local blood bank. Objective: To identify the frequency of ABO blood group and RH factors distribution on voluntary blood donator at Debre Tabor blood bank from May 2014 to May 2020. Methods: A retrospective cross-sectional survey was conducted to identify the frequency of ABO and Rh factor distribution on voluntary blood donors at Debre Tabor town blood bank. The data was collected at Debre Tabor blood bank. A six-year data and a total of 19,901 bags collected blood samples were used for summarization of the data. The data was analysed by using SPSS version 21. Results: Blood group "O" was the dominated one with 39.6% followed by blood group "A", "B" and "AB" with 29.48%, 24.06%, and 6.7%, respectively. When we see the RH classifications, RH positive accounts the highest percentage 92.77% and the remaining 7.23% was Rh negatives. Conclusion: In this survey, the majority of blood groups were found "O" followed by "A", "B", and "AB". Among the collected blood unities, 92.77% was RH positive. The leading blood donators were male. [ABSTRACT FROM AUTHOR]

Background: The ABO blood group and Rhesus (Rh) factor remain the most important blood group in transfusion medicine. Knowledge of ABO and rhesus blood group distribution within a population is indispensable for transfusion medicine, clinical and marriage counselling. Aims and Objectives: The objectives of this study were to provide data and compare the pattern of ABO and rhesus blood group distribution between a homogenous and a heterogenous population. Material and Methods: Blood was collected from 352 University students representing a heterogenous population and 235 primary school pupils in a local community representing homogenous population. The ABO and rhesus blood groups were determined using white tile and agglutination methods. Results: Among the 352 and 235 individuals studied in UNN and HFNP, blood groups O had the highest frequency with 54.80% and 51.06% respectively while blood group AB had the least frequency of 4.50% and 3.40% in UNN and HFNP respectively. Rhesus positive had the highest frequency of 88.63% and 95.33% while rhesus negative had the frequencies of 11.35% and 4.68% in UNN and HFNP respectively. Rhesus negative was highest among females in UNN 26 (7.37%) while males had the highest rhesus negative 7 (2.98%) in HFNP. In both study populations, there was no significant difference in ABO and rhesus blood group distribution between the males and females (P > 0.05). Conclusions: A homogenous population is associated with low prevalence of rhesus negative compared to a heterogenous population. [ABSTRACT FROM AUTHOR]

Introduction: ABO and Rh-blood groups vary among different populations in the world. Also, this variability of blood groups has been observed in different geographical regions and populations within a country. Determination of ABO and Rhblood group distribution in a country plays an important role in blood transfusion and many fields of medicine. Aim: To determine distribution of ABO and Rh-blood groups among patients admitted to gynaecology, obstetrics and children Hospital in Konya, Turkey. Materials and Methods: A total of 30291 patients were included to this retrospective study between September 2015-December 2017 for a period of 27 months. Patients were divided into two major groups according to age. There were 29548 (97.5%) women in the age group of 17-75 and they admitted to gynaecology and obstetrics departments. The number of children in the age group of 0-16 were 743 (2.5%) and they were admitted to paediatrics departments. ABO and Rh-blood group tests were performed by gel centrifugation method on fully automated immunohematology analyser. Data analyses were performed by using chi-Square and Monte Carlo exact test. Results: A Rh-positive had the highest rates (37% and 35.4%) among women and children, respectively and was followed by O Rh-positive (28.4%, 29.8%), B Rh-positive (16.1%, 16.9%) and AB Rh-positive (7.3%, 6.8%). AB Rh-negative had the lowest frequency as its rate was under 1%. The rate of Rh positivity was 89% and that of Rh negativity was found to be 11% in both study groups. Distribution of blood groups according to gender among children population was not found statistically significant (p>0.05). Conclusion: The present results were similar to data obtained from previous studies in Turkey, but indicated a different ABO and Rh-blood group profile compared to many studies worldwide because of genetic and ethnic factors. Authors think the present study will contribute to literature by reporting the knowledge of blood group distribution in different populations and creating a database for blood banks in our country. [ABSTRACT FROM AUTHOR]

Objective: To explore the relationship of type 2 diabetes (T2DM) with different blood groups (A, B, AB and O) and Rhesus factor (positive or negative). Settings and duration: The study was conducted at the Biochemistry Department of Baqai Medical University from January 2015 to December 2015. Subjects and Methods: A total of 400 individuals were enrolled with 200 known type 2 diabetic patients and 200 healthy controls. Written informed consent was obtained from each study participant. Convenient sampling technique was adopted. Blood grouping procedure was based on Agglutination principle. The quantitative determination of hemoglobin A1C was done in hemosylate derived from whole blood on Roche automated clinical chemistry analyzer. Results: It was observed that blood group B was significantly more common among diabetic subjects (p-value <0.05), whereas blood group A was significantly less common in diabetic subjects as compared to non-diabetic subjects (p-value <0.05). No significant difference was found in terms of Rhesus factor among diabetic and nondiabetic subjects. Conclusion: The outcomes suggest that frequency of blood group B is significantly higher in type 2 diabetes while frequency of blood group A is significantly lower in type 2 diabetes as compared to non-diabetes. Further larger scale community based studies are needed to ascertain the findings of this study. [ABSTRACT FROM AUTHOR]

Summary: Background/Objectives: Alopecia areata (AA) is an autoimmune disease characterized by noncicatricial hair loss localized on hair, beard, mustache, eyebrow, eyelash, and sometimes on the body. Although etiopathogenesis is not fully understood, many studies show remarkable associations between various diseases and ABO blood groups. However, there is no study with AA and blood groups. Methods: Healthy people and patients with AA were included in this study. A total of 155 patients with AA and 299 healthy controls were included in the study. Results: ABO blood group distribution in patients with AA and distribution of healthy donors were similar. However, Rhesus factor positivity in the AA group was significantly higher than in healthy donors. The relationship between stress and AA was high as known. But, ABO blood group and Rhesus factor were not in a significant connection with stress. Conclusion: We conclude that there was no association between ABO blood group and AA, but the observed distribution of Rhesus blood group differed slightly but significantly from that of the healthy population. The result of the study shows a small but statistically significant difference in the Rh blood group between patients with AA and the healthy population blood groups. This result is important because it suggests that genetic factors may influence the development of AA. The role of blood groups in the development of AA remains to be determined. We believe that the studies which will be carried out in other centers with wider series will be more valuable to support this hypothesis. [ABSTRACT FROM AUTHOR]

Introduction: Although several studies have investigated the relationship between ABO blood group and medical diseases, few reports have explored the association with oral diseases, including periodontal disease (PD). Aim: The aim of this literature review was to assess the association between the ABO blood grouping and PD. Methods: We searched PubMed and Google Scholar databases using the following terms in different combinations: "ABO blood group," "periodontitis," "aggressive periodontitis (AP)," "risk factor," and "Rhesus factor." Databases were searched for articles published from 1977 to August 2016. Titles and abstracts of articles were screened for English-language papers describing clinical studies, case reports, or retrospective studies of oral health status in patients with different ABO blood groups. Letters to the editor, historic reviews, and articles including unpublished data were excluded. Reference lists of included studies were reviewed for additional original and review studies. Results: We identified eight articles describing studies of the relationship between ABO blood groups and PD. The findings suggested a possible genetic basis in the association of the blood group AB with AP. Four studies showed that chronic periodontitis was more common among patients with blood group O. Conclusion: ABO blood subgroup and Rhesus factor could constitute risk predictors in the development of PD. [ABSTRACT FROM AUTHOR]

Background and Aims: Helicobacter pylori infection currently become as an endemic worldwide health issue. The infection causes variety of gastrointestinal diseases. The role of blood groups is established in body's response to microorganisms and the development of gastrointestinal disorders. This study aimed to investigate the relationship between blood groups, age and gender of Iranian population and the severity of infection with this bacteria. Materials and Methods: The study included 160 patients with dyspepsia symptoms referred to Hajar hospital in Shahrekord. Biopsy specimens were investigated in terms of being infected with H. pylori by using PCR for 16SRNA gene and glmM gene and blood groups of patients were determined by using hemagglutination routine test. Results and Conclusions: It was observed that 61.87% of patients were positive in terms of bacteria existence and 61 of them were negative. 62.26% of infected patients with bacteria were female. The highest frequency of ABO blood groups among infected patients, belongs to O blood group with 40.66 percent (P>0.05). H. pylori was found in 77.12% of Rh+ patients (P<0.05). There is not significant relation between sex and age with infection (p> 0.05). The severity of this bacterial disease were observed in patients with blood group O more than others (P< 0.05). Rh positive in infected patients and O blood group may cause to severity of H. pylori infection. [ABSTRACT FROM AUTHOR]

Aim of investigation. To detect phenotypic and genotypic features of the full-term newborns with delayed conjugation jaundice in relation to gender of the patient.Material and methods. The group of full-term children (n=251) with delayed conjugation jaundice was investigated, that have been divided in two subgroups according to gender. All patients underwent complex clinical and laboratory, instrumental and immunologic investigation. Features of pregnancy and delivery course, weight and height scores and children disease spectrum, blood groups and Rhesus factor were investigated.Results. It was known, that prevailing genotypic changes in boys – increased proportion of 0 (I) groups and decreased proportion of A (II) blood group, as well as increase of proportion of phenotypes 0 Rh + and decrease of A Rh + in boys prevail in comparison to girls and control group, while in girls environmental factors (complicated course of pregnancy and delivery) have more pronounced effect. Boys and girls differ by disease spectrum. Assessment of these diseases shows, that state of girls was more severe.Conclusions. The original study allows to conclude, that children with delayed conjugation jaundice in neonatal period belong to risk group for development of complications at action of harmful external factors over the liver.

Aim: Telogen effluvium(TE) in women is a common problem in dermatology and has multiple etiologic causes. Low iron stores can be a possible contributing factor in TE. Although etiopathogenesis is not fully understood, many studies show remarkable associations between various diseases and ABO blood groups. Genomewide association studies have reported alleles in the ABO locus to be associated with ferritin levels. We had done this study with TE patients to detect serum ferritin levels and to find this relation between blood groups. Material and Methods: Healthy people and patients with TE were included in this study. A total of 103 females who have telogen effluvium and 125 controls were included. Results: ABO blood group and Rhesus factor distribution in patients with TE and distribution of healthy donors were similar. There haven't any significant association between ferritin levels and blood groups in TE patients. Conclusion: There are many different causes in TE etiology, for this reason in our opinion, ferritin levels and other laboratory tests must be done. We conclude that there was no evocation between ABO blood groups, Rhesus factor and ferritin levels in TE, but this is the first study that can show this relationship and can be important for new studies which will be carried out in other centers with wider series. [ABSTRACT FROM AUTHOR]

The present study sought to expand the limited evidence that sexual orientation is influenced by genetic factors. This was accomplished by seeking statistical differences between heterosexuals and homosexuals for four traits that are known to be genetically determined: eye color, natural hair color, blood type, and the Rhesus factor. Using a sample of over 7,000 U.S. and Canadian college students supplemented with additional homosexual subjects obtained through internet contacts, we found no significant differences between heterosexuals and homosexuals regarding eye color or hair color. In the case of blood type and the Rh factor, however, interesting patterns emerged. Heterosexual males and females exhibited statistically identical frequencies of the A blood type, while gay men exhibited a relatively low incidence and lesbians had a relatively high incidence ( p < .05). In the case of the Rh factor, unusually high proportions of homosexuals of both sexes were Rh− when compared to heterosexuals ( p < .06). The findings suggest that a connection may exist between sexual orientation and genes both on chromosome 9 (where blood type is determined) and on chromosome 1 (where the Rh factor is regulated). [ABSTRACT FROM AUTHOR]