1. Age-related differences in the impact of coagulopathy in patients with isolated traumatic brain injury: An observational cohort study
- Author
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Akira Endo, Kiyoshi Murata, Wataru Takayama, Yasuhiro Otomo, and Hazuki Koguchi
- Subjects
Adult ,Male ,medicine.medical_specialty ,Traumatic brain injury ,Glasgow Outcome Scale ,Critical Care and Intensive Care Medicine ,03 medical and health sciences ,0302 clinical medicine ,Japan ,Risk Factors ,Internal medicine ,Age related ,Brain Injuries, Traumatic ,medicine ,Coagulopathy ,Humans ,In patient ,Hospital Mortality ,International Normalized Ratio ,Aged ,Retrospective Studies ,Abbreviated Injury Scale ,business.industry ,Age Factors ,030208 emergency & critical care medicine ,Retrospective cohort study ,Level iv ,Blood Coagulation Disorders ,Middle Aged ,medicine.disease ,Logistic Models ,Multivariate Analysis ,Surgery ,Female ,business ,Cohort study - Abstract
Background Although age and trauma-induced coagulopathy (TIC) are well-known predictors of poor outcome after traumatic brain injury (TBI), the interaction effect of these two predictors remains unclear.Objectives We assessed age-related differences in the impact of TIC on the outcome following isolated TBI.Methods We conducted a retrospective observational study in two tertiary emergency critical care medical centers in Japan from 2013 to 2018. A total of 1036 patients with isolated TBI [head abbreviated injury scale (AIS) ≥3, and other AIS
- Published
- 2020