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Start Over Author "Cheraghi Z" Topic biotransformation (metabolism)
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1. Nitrile biotransformation by whole cells of Aspergillus sp. PTCC 5266.

Author

Yousefi, M., Mohammadi, M., Habibi, Z., and Cheraghi, Z.

Subjects
NITRILES, BIOTRANSFORMATION (Metabolism), ASPERGILLUS, HYDRATION, CARBOXYLIC acids, AMIDES, PH effect, FUNCTIONAL groups
Abstract

Aspergillus sp. PTCC 5266 exhibited nitrile-hydrating activity over a broad pH range from 6.0 to 10.0 at 26°°C. It hydrated 4-nitrophenylacetonitrile, 2-chlorobenzonitrile and 3-chlorobenzonitrile to their corresponding carboxylic acids and amides, while benzyl cyanide, benzonitrile, 4-tolunitrile, cyclohexanecarbonitrile, 4-chlorobutyronitrile and isobutyronitrile gave carboxylic acids as the sole products. The maximum whole-cell nitrile-hydrating activity was observed at pH 7.0. [ABSTRACT FROM AUTHOR]

Published
2011
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