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17 results on '"Jon Andresen"'

2. Hyperthermia: from diagnostic and treatments to new discoveries

Author

Marco Brotto, Sandra Romero-Suarez, Thomas M. Nosek, Eduardo Abreu, Leticia Brotto, Chenglin Mo, Simon Kaja, Kendra Baker, Jon Andresen, Michael J. Wacker, Chad D. Touchberry, Nuria Lara, Wolfgang H. Dillmann, Robin Craig, and Ruben Mestril

Subjects
Hyperthermia, medicine.medical_specialty, Magnetic Resonance Spectroscopy, Muscle Fibers, Skeletal, Bioengineering, HSP72 Heat-Shock Proteins, Mice, Transgenic, Biology, In Vitro Techniques, Applied Microbiology and Biotechnology, Article, Muscle hypertrophy, Mice, In vivo, Internal medicine, medicine, Myocyte, Animals, Homeostasis, Humans, Phosphorylation, Heat-Shock Proteins, Regulation of gene expression, Muscle Cells, Hyperthermia, Induced, medicine.disease, Neoplasm Proteins, Endocrinology, Calcium, Signal transduction, Neuroscience, Ex vivo, Intracellular, Heat-Shock Response, Biotechnology, Molecular Chaperones, Signal Transduction
Abstract

Hyperthermia is an important approach for the treatment of several diseases. Hyperthermia is also thought to induce hypertrophy of skeletal muscles in vitro and in vivo, and has been used as a therapeutic tool for millennia. In the first part of our work, we revise several relevant patents related to the utilization of hyperthermia for the treatment and diagnostic of human diseases. In the second part, we present exciting new data on the effects of forced and natural overexpression of HSP72, using murine in vitro (muscle cells) and ex vivo (primary skeletal muscles) models. These studies help to demonstrate that hyperthermia effects are orchestrated by tight coupling between gene expression, protein function, and intracellular Ca(2+) signaling pathways with a key role for calcium-induced calcium release. We hope that the review of current patents along with previous unknown information on molecular signaling pathways that underlie the hypertrophy response to hyperthermia in skeletal muscles may trigger the curiosity of scientists worldwide to explore new inventions that fully utilize hyperthermia for the treatment of muscle diseases.

Published
2012

4. Impaired vascular function in female Dentin matrix protein 1 null mice

Author

Michael J. Wacker, Jon Andresen, Marco Brotto, Lynda F. Bonewald, and Neerupma Silswal

Subjects
Null mice, Pathology, medicine.medical_specialty, Viral matrix protein, business.industry, Anatomy, Biochemistry, medicine.anatomical_structure, Genetics, Dentin, medicine, business, Vascular function, Molecular Biology, Biotechnology
Published
2011
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6. Evidence for pathophysiological crosstalk between bones, cardiac, skeletal and smooth muscles

Author

Mark S. Johnson, Lynda F. Bonewald, Neerupma Silswal, Michael J. Wacker, Marco Brotto, Leticia Brotto, Chad D. Touchberry, Jinhua Shen, C-K Qu, Robin Craig, Michael Loghry, Jon Andresen, Nikhil K. Parelkar, and Todd Hall

Subjects
Crosstalk (biology), business.industry, Genetics, Medicine, business, Molecular Biology, Biochemistry, Neuroscience, Pathophysiology, Biotechnology
Published
2010
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8. PPARα agonists acutely dilate the mouse middle cerebral artery

Author

Nikhil K. Parelkar, Jon Andresen, and Mostafa Z. Badr

Subjects
medicine.medical_specialty, Endocrinology, business.industry, PPAR-alpha Agonists, Internal medicine, medicine.artery, Middle cerebral artery, Genetics, medicine, business, Molecular Biology, Biochemistry, Biotechnology
Published
2010
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9. Mild Heat Shock Promotes Hypertrophy in Cardiac, Skeletal and Smooth Muscle Cells

Author

Neerupma Silswal, Christopher J Elmore, Kendra Baker, Todd Hall, Chad D. Touchberry, Robin A. Craig, Jon Andresen, Michael J. Wacker, and Marco Brotto

Subjects
medicine.medical_specialty, Mild heat, Chemistry, Biochemistry, Muscle hypertrophy, Endocrinology, Smooth muscle, Internal medicine, Shock (circulatory), Genetics, medicine, Myocyte, medicine.symptom, Molecular Biology, Biotechnology
Published
2010
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13. Mouse cerebral arteries dilate to carbon monoxide

Author

Jon Andresen and Robert Bryan

Subjects
medicine.medical_specialty, chemistry.chemical_compound, Chemistry, Internal medicine, Cerebral arteries, Genetics, medicine, Cardiology, Molecular Biology, Biochemistry, Biotechnology, Carbon monoxide
Published
2006
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17. Erythropoietin dilates cerebral vessels

Author

Robert Bryan, Jon Andresen, and Nadeem Iqbal Shafi

Subjects
medicine.medical_specialty, business.industry, Erythropoietin, Internal medicine, Genetics, Cardiology, Medicine, business, Molecular Biology, Biochemistry, Biotechnology, medicine.drug
Published
2006
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