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1. Development of a Guinea Pig Model of Chronic Asthma with Markedly Thickened Airway Walls: Two Studies Using This Animal Model.

Author

Yoshida, Minoru, Toda, Masao, Sagara, Hironori, Nakano, Yasuhiro, Hiyama, Takako, and Fukuda, Takeshi

Subjects
*GUINEA pigs as laboratory animals, *ASTHMA, *AIRWAY (Anatomy), *RESPIRATION, *ANTIGENS, *BIOPSY
Abstract

Provides information on a study which developed a guinea pig model of chronic asthma with markedly thickened airway walls by repeated antigen challenge in sensitized animals, to assess questions in regard to airway remodeling. Element which is thought to correspond to bronchial biopsy sites in humans; Overview of the model; Measurement of airway hyper-responsiveness.

Published
2001
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