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Your search keyword '"EOE"' showing total 2 results
2 results on '"EOE"'

1. Differences in Management of Eosinophilic Esophagitis in Europe: An Assessment of Current Practice

Author

Eleftheria Roma, Gilles Tourlamain, Noam Zevit, Jorge Amil Dias, Christiane Sokollik, Roger Garcia-Puig, Carolina Gutiérrez-Junquera, Johanna H. Oudshoorn, Caterina Strisciuglio, Kasia Karolewska-Bochenek, Marcus Karl-Heinz Auth, Orel Rok, Mike Thomson, Saskia Vande Velde, Salvatore Oliva, Aco Kostovski, Christos Tzivinikos, Alexandra Papadopoulou, Nicolas Kalach, Vaidotas Urbonas, O. Bauraind, Sebastian Otte, Tourlamain, G., Garcia-Puig, R., Gutierrez-Junquera, C., Papadopoulou, A., Roma, E., Kalach, N., Oudshoorn, J., Sokollik, C., Karolewska-Bochenek, K., Oliva, S., Strisciuglio, C., Bauraind, O., Auth, M. K. -H., Thomson, M., Otte, S., Rok, O., Dias, J. A., Tzivinikos, C., Urbonas, V., Kostovski, A., Zevit, N., and Velde, S. V.

Subjects
esophagitis, diagnosis, CHILDREN, GUIDELINES, Pediatrics, 0302 clinical medicine, Medicine and Health Sciences, Medicine, Child, medicine.diagnostic_test, treatment, adult, pediatric, Gastroenterology, Perinatology, Clinical Practice, and Child Health, Europe, diagnosi, VARIABILITY, Current practice, General practice, 030211 gastroenterology & hepatology, France, Esophageal dysfunction, Adult, medicine.medical_specialty, GASTROENTEROLOGISTS, CONSENSUS RECOMMENDATIONS, 03 medical and health sciences, 030225 pediatrics, Internal medicine, Biopsy, EOE, Humans, In patient, Eosinophilic esophagitis, Portugal, business.industry, esophagiti, Proton Pump Inhibitors, ADULTS, Eosinophilic Esophagitis, medicine.disease, United Kingdom, Spain, Pediatrics, Perinatology and Child Health, Poland, business, Esophagitis
Abstract

OBJECTIVES The aim of the study was to assess differences in the diagnosis and management of eosinophilic esophagitis (EoE) by European pediatric (PG) and adult gastroenterologists (AG), and their self-reported adherence to guidelines. METHODS A multiple-choice questionnaire gauged the diagnostic and management strategies of gastroenterologists treating children or adults in 14 European countries and the United Arab Emirates (UAE). RESULTS Questionnaires were completed by 465 PG and 743 AG. PG were significantly more likely to take biopsies in patients with symptoms of esophageal dysfunction (86.2% PG vs 75.4% AG, P

Published
2020

2. Fluticasone and food allergen elimination reverse sub-epithelial fibrosis in children with eosinophilic esophagitis.

Author

Abu-Sultaneh, Samer, Durst, Paul, Maynard, Virginia, Elitsur, Yoram, and Abu-Sultaneh, Samer M A

Subjects
*FIBROSIS, *ESOPHAGUS diseases, *DEGLUTITION disorders, *JUVENILE diseases, *BIOPSY, *EOSINOPHILS, *ALLERGENS, *FOOD allergy, *THERAPEUTICS
Abstract

Background: Symptoms of vomiting and dysphagia in children with eosinophilic esophagitis may be related to the development of mucosal fibrosis.Aim: Our aims were to (1) investigate esophageal fibrosis in children with EoE compared to patients with gastroesophageal reflux disease and normal individuals, and (2) to assess the degree of mucosal fibrosis in patients with EoE before and after medical treatment.Methods: A retrospective analysis of esophageal biopsies from patients with EoE, GERD, and normal mucosa was performed. Demographic data, clinical information, eosinophil number, and sub-epithelial fibrosis was compared among the groups. A similar comparison was performed in EoE patients, before and after therapy.Results: Esophageal biopsies from 53 children were included, of which 17 with EoE, 17 GERD, and 19 were normal. A significantly higher number of eosinophils and greater fibrosis was found in EoE patients vs. GERD and normal (fibrosis grade 2: 13 patients in the EoE group vs. one patient for each control group; p=0.0001). After therapy, a significant decrease in fibrosis and eosinophils number was noted in EoE patients [fibrosis grade 2: 10 (71.5%) patients vs. one (7.1%) patient, and eosinophil count was 35.5/HPF vs. 13.4/HPF, pre- and post-therapy, respectively; p<0.05]. The decrease in esophageal fibrosis paralleled the improvement in the related clinical symptoms.Conclusion: A higher degree of esophageal fibrosis was found in patients with EoE compared to GERD or normal esophagus. Conventional therapy in EoE improved obstructive symptoms, decreased eosinophils count, and reversed the degree of fibrosis. We suggest that appropriate therapy in patients with EoE will improve clinical symptoms and histology. [ABSTRACT FROM AUTHOR]

Published
2011
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