1. Pure word deafness associated with extrapontine myelinolysis
- Author
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Mingwei Xu, Ren-jing Zhu, Benyan Luo, Zhi-su Lv, and Chun-lei Shan
- Subjects
Adult ,medicine.medical_specialty ,Extrapontine myelinolysis ,Cortical deafness ,Auditory agnosia ,Audiology ,General Biochemistry, Genetics and Molecular Biology ,Aphasia ,otorhinolaryngologic diseases ,medicine ,Humans ,Brain magnetic resonance imaging ,Hearing Loss, Central ,General Pharmacology, Toxicology and Pharmaceutics ,General Veterinary ,business.industry ,General Medicine ,medicine.disease ,Biomedicine ,Myelinolysis, Central Pontine ,Central pontine myelinolysis ,Female ,medicine.symptom ,Hyponatremia ,business ,Word deafness - Abstract
Extrapontine myelinolysis and pure word deafness are very uncommon disorders. Here, we report a case of a 19-year-old woman who suffered from osmotic demyelination syndrome with coincidence of typical pure word deafness. As a consequence of rapid correction of hyponatremia, the patient demonstrated an initial onset of cortical deafness, and then progressed to generalized auditory agnosia, which eventually developed into confined verbal auditory agnosia (pure word deafness). Bilateral extrapontine myelinolysis was confirmed using brain magnetic resonance imaging. This case suggests that verbal and nonverbal stimuli may involve separate thalamocortical pathways.
- Published
- 2010
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