1. SARS-CoV-2 incidence, testing rates, and severe COVID-19 outcomes among people with and without HIV
- Author
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Spinelli, Matthew A, Brown, Lillian B, Glidden, David V, Hunter, Kyle, Martin-Tuite, Patrick, Zheng, James, Sera, Curtis, Havlir, Diane, Buchbinder, Susan P, and Gandhi, Monica
- Subjects
Biomedical and Clinical Sciences ,Public Health ,Health Sciences ,Emerging Infectious Diseases ,Coronaviruses ,Coronaviruses Disparities and At-Risk Populations ,Prevention ,Lung ,Sexually Transmitted Infections ,Clinical Research ,HIV/AIDS ,Infectious Diseases ,Infection ,Good Health and Well Being ,COVID-19 ,COVID-19 Vaccines ,HIV Infections ,Humans ,Incidence ,SARS-CoV-2 ,Biological Sciences ,Medical and Health Sciences ,Psychology and Cognitive Sciences ,Virology ,Biomedical and clinical sciences ,Health sciences - Abstract
To assess SARS-CoV-2 outcomes, we matched a municipal COVID-19 registry and clinic rosters from a municipal primary care network containing a large HIV clinic and assessed clinical outcomes by HIV status. The risk of severe COVID-19 was higher among people with HIV (PWH, adjusted relative risk = 1.84, 95% confidence interval = 1.05-3.25), while SARS-CoV-2 incidence was lower despite higher testing rates. SARS-CoV-2 vaccination campaigns should prioritize PWH to prevent severe COVID-19 disease given potentially higher risk.
- Published
- 2021