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ABSTRACT The aim of research was to elaborate the non-biodegradable (made of polypropylene (PP)) and resorbable (made of polylactide (PLA)) tubular fibrous structures for the reconstruction of the vascular vessels. For the mentioned structures design, nonconventional manufacturing techniques such as melt blown, melt electrospinning, and melt electroblowing were used. Three techniques were chosen as methods allowing on the fibrous structures manufacture containing fibers in nano- or submicro-size diameter. Other advantages of free-solvent technique use is the reduction in the clinical adverse events associated with solvent resided in the fibrous structure during the fabrication. The tubular fibrous structures of PP and PLA using above-mentioned techniques were designed. In first stage, the analysis of the processing parameters influence on the nonbiodegradable and biodegradable tubular structures fiber diameter was performed. Subsequently, the validation step was the analysis of the influence of processing parameters on PP and PLA structural properties for each manufacturing techniques was investigated. The research results confirmed the ability of the tubular structures manufacture with various fiber diameter depending on the applied technique and processing parameters. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40147. [ABSTRACT FROM AUTHOR]

The general objective of this research is to use melt electrospinning to design and fabricate semibiodegradable and multilayered fibrous structures that have potential applications for cardiovascular implants, including small-diameter (<6 mm) blood vessels replacements. In the first stage of the study, as described in this article, flat fibrous structures from polypropylene and polylactide polymers were fabricated. The fabrication stage was necessary to determine the effect of the polymers' melt mass flow rate, melt electrospinning processing parameters (as a working distance and spinning voltage) on the resulting fiber diameter and on other physical and structural properties of the fibrous structures. An analysis of the effects of the processing parameters on the fabrication of the fibrous structures and the selection of the appropriate polymers for the final multilayered tubular structure were also performed. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013 [ABSTRACT FROM AUTHOR]

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