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Biomarkers have already been proposed as powerful classification features for use in the training of neural network-based and other machine learning and artificial intelligence-based prognostic models in the scientific field of personalized nutrition. In this paper, we construct and study cascaded SVM-based classifiers for automated metabolic syndrome diagnosis. Specifically, using blood exams, we achieve an average accuracy of about 84% in correctly classifying body mass index. Similarly, cascaded SVM-based classifiers achieve a 74% accuracy in correctly classifying systolic blood pressure. Next, we propose and implement a system that achieves an 84% accuracy in metabolic syndrome prediction. The proposed system relies not only on prediction of the body mass index but also on prediction from blood exams of total cholesterol, triglycerides and glucose. For the aim of self-completeness of the paper, the key concepts with regard to metabolic syndrome are summarized, and a review of previous related work is included. Finally, conclusions are drawn and indications for related future research are outlined. [ABSTRACT FROM AUTHOR]

The doctrine of the "one size fits all" approach in the field of disease diagnosis and patient management is being replaced by a more per patient approach known as "personalized medicine". In this spirit, biomarkers are key variables in the research and development of new methods for prognostic and classification model training based on advances in the field of artificial intelligence [1, 2, 3]. Metabolomics refers to the systematic study of the unique chemical fingerprints that cellular processes leave behind. The metabolic profile of a person can provide a snapshot of cell physiology and, by extension, metabolomics provide a direct "functional reading of the physiological state" of an organism. Via employing machine learning methodologies, a general evaluation chart of nutritional biomarkers is formulated and an optimised prediction method for body to mass index is investigated with the aim to discover dietary patterns. [ABSTRACT FROM AUTHOR]

Biomarkers are measurements of biological variables that can determine a state of health. They consist of measuring a single variable or a combination of variables related to the state of health that these variables represent. Biomarkers can provide an early warning of a health problem in relation to an individual patient or group of patients, and thus trigger actions and lead to interventions. Nutritional biomarkers measure the biological consequences of one's diet. In our recent work, we have used machine learning to predict weight, metabolic syndrome and blood pressure, using blood-exam-based biomarkers. In the current work, we use extreme value theory to examine the significance of outliers in health data, with a focus on diet and the standard biochemistry profile. Specifically, we show that, using extreme value analysis and by applying a systemisation of the process, health trends can be predicted, and thus, health interventions can be (at least partially) automated. For that purpose, public access datasets have been used, which were retrieved from the National Health and Nutrition Examination Survey. The NHANES is a program of studies designed to assess the health and nutritional status of the population in the United States. In total, about 70,000 datapoints were analysed, covering about a decade's worth of observations. [ABSTRACT FROM AUTHOR]