Search

Your search keyword '"J M, Hofstra"' showing total 1 results
Start Over Author "J M, Hofstra" Topic biomarkers
1 results on '"J M, Hofstra"'

1. Anti-PLA₂R antibodies in membranous nephropathy: ready for routine clinical practice?

Author

J M, Hofstra and J F, Wetzels

Subjects
Receptors, Phospholipase A2, Humans, Glomerulonephritis, Membranous, Severity of Illness Index, Biomarkers, Autoantibodies
Abstract

The identification of circulating autoantibodies against the M-type phospholipase A₂ receptor (anti-PLA₂R) in patients with idiopathic membranous nephropathy (iMN) has been a major discovery. Anti-PLA₂R can be measured by a commercially available test. It is suggested that measurement of anti-PLA₂R will change the diagnostic strategy in patients with nephrotic syndrome and may guide treatment in patients with iMN. We review the available evidence and caution against the immediate injudicious use of the assay in routine clinical practice.

Published
2012

Catalog

Books, media, physical & digital resources
See catalog results