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Your search keyword '"Diet-related disease"' showing total 3 results
Start Over Descriptor "Diet-related disease" Topic biomarkers
3 results on '"Diet-related disease"'

1. Metabolomic applications in nutritional research: a perspective.

Author

O'Gorman, Aoife and Brennan, Lorraine

Subjects
*METABOLITES, *NUCLEAR magnetic resonance, *MASS spectrometry, *MULTIVARIATE analysis, *BIOMARKERS
Abstract

Metabolomics focuses on the global study of metabolites in cells, tissues and biofluids. Analytical technologies such as nuclear magnetic resonance ( NMR) spectroscopy and hyphenated mass spectrometry ( MS) combined with advanced multivariate statistical methods allow us to study perturbations in metabolism. The close link between metabolism and nutrition has seen the application of metabolomics in nutritional research increase in recent times. Such applications can be divided into three main categories, namely (1) the area of dietary biomarker identification, (2) diet-related diseases and (3) nutritional interventions. The present perspective gives an overview of these applications and an outlook to the future. © 2015 Society of Chemical Industry [ABSTRACT FROM AUTHOR]

Published
2015
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2. Metabolomics of diet-related diseases using mass spectrometry.

Author

Armitage, Emily G., Rupérez, Francisco J., and Barbas, Coral

Subjects
*METABOLOMICS, *FOODBORNE diseases, *MASS spectrometry, *BIOMARKERS, *MEDICAL screening, *GENETIC regulation
Abstract

Highlights: [•] Mass spectrometry-based metabolomics applied to study diet-related diseases. [•] Selected biomarkers aid understanding of disease mechanisms. [•] Different analytical platforms (CE–MS, GC–MS, LC–MS) offer different information. [•] Integrated biology (different omics) reveals more information on pathway regulation. [Copyright &y& Elsevier]

Published
2013
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3. Advanced glycation end products as biomarkers in systemic diseases: premises and perspectives of salivary advanced glycation end products

Author

Massimo Collino, Anida Maria Băbţan, Radu S Câmpian, Aranka Ilea, Maria Crisan, Jared Q. Gerlach, Bianca Bosca, Rosa M. Sainz, and Nausica Bianca Petrescu

Subjects
Glycation End Products, Advanced, Food intake, Aging, Clinical Biochemistry, Inflammation, Disease, 030204 cardiovascular system & hematology, chronic low-level inflammation, Bioinformatics, Premises, biosensor, AGEs, metabolic syndrome, Proinflammatory cytokine, 03 medical and health sciences, 0302 clinical medicine, Glycation, Drug Discovery, medicine, Animals, Humans, metainflammation, Saliva, business.industry, advanced glycation end products, Biochemistry (medical), AGEs diagnosis and downregulation, medicine.disease, 030220 oncology & carcinogenesis, Food products, biomarkers, diet-related disease, saliva, medicine.symptom, Metabolic syndrome, business, Biomarkers
Abstract

Advanced glycation end products (AGEs) are glycated proteins associated with high dry temperature food processing, coloring and flavor modification of food products. Previous studies on diet-related disease support the role of the glycation products as biomarkers in local and general proinflammatory response. Exogenous and endogenous AGEs are involved in chronic low-level inflammation, which underlies the onset of metabolic syndrome influenced by food intake, there by demonstrating their implication in diet-related pathologies. Although studies have revealed a strong association between the accumulation of AGEs and the occurrence/worsening of metabolic diseases, their routine use for the diagnosis or monitoring of local and general disease has not yet been reported.

Published
2019

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