1. No association between iron status and self-reported health-related quality of life in 16,375 Danish blood donors: results from the Danish Blood Donor Study
- Author
-
Sebastian Kotzé, Christian Erikstrup, Cecilie J. Sørensen, Ole Birger Pedersen, Andreas S. Rigas, Mikkel Steen Petersen, Lise Wegner Thørner, Erik Sørensen, Henrik Ullum, and Henrik Hjalgrim
- Subjects
Pediatrics ,medicine.medical_specialty ,biology ,business.industry ,Anemia ,Immunology ,C-reactive protein ,Hematology ,Iron deficiency ,medicine.disease ,Mental health ,humanities ,language.human_language ,Danish ,Quality of life ,Internal medicine ,biology.protein ,language ,Immunology and Allergy ,Medicine ,business ,Body mass index ,Cohort study - Abstract
BACKGROUND Health-related quality of life (HRQL) represents people's subjective assessment of their mental and physical well-being. HRQL is highly predictive of future health. The effect of iron deficiency without anemia induced by blood donation on HRQL is presently unknown. The aim was to explore the relationship between iron status and self-reported mental component score (MCS; SF-12) and physical component score (PCS; SF-12) in Danish blood donors. STUDY DESIGN AND METHODS Complete relevant data, including the 12-item short-form health survey (SF-12), plasma ferritin levels, age, body mass index, smoking status, C-reactive protein levels, number of donations in the previous 3 years, and PCS and MCS, were available for 8692 men and 7683 women enrolled from March 1, 2010, to December 31, 2010. Multivariable linear and logistic (cutoff at the 10th percentile) regression analyses were used to assess the relationship between iron deficiency (ferritin
- Published
- 2015