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Start Over Descriptor "MESH: vertigo" Topic biology.organism_classification
3 results on '"MESH: vertigo"'

1. Efficacy of acetylleucine in vertigo and dizziness: a systematic review of randomised controlled trials

Author

Florian Naudet, Rémy Boussageon, Helene Vaillant Roussel, Nematollah Jaafari, Clara Blanchard, Denis Pouchain, Paul Vanderkam, Marie Christine Perault-Pochat, Département de Médecine Générale, Université de Poitiers (DMG), Université de Poitiers - Faculté de Médecine et de Pharmacie, Université de Poitiers-Université de Poitiers, Unité de Recherche Clinique [CH Henri Laborit, Poitiers], Centre Hospitalier Henri Laborit (CHL), Centre d'Investigation Clinique [Rennes] (CIC), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Département de Médecine Générale [CHRU Tours], Université Francois Rabelais [Tours]-Centre Hospitalier Régional Universitaire de Tours (CHRU TOURS), AutomédiCation aCcompagnement Pluriprofessionnel PatienT (ACCePPT), Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), Departement Médecine Générale [Clermont-Ferrand] (UFR Médecine), Université d'Auvergne - Clermont-Ferrand I (UdA), Service de pharmacologie clinique et de sensibilisation [CHU Poitiers], Centre hospitalier universitaire de Poitiers (CHU Poitiers), CIC - Poitiers, Université de Poitiers-Centre hospitalier universitaire de Poitiers (CHU Poitiers)-Direction Générale de l'Organisation des Soins (DGOS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Groupement de recherche en Psychiatrie (GDR Psychiatrie (3557)), Centre National de la Recherche Scientifique (CNRS), Evaluation et modélisation des effets thérapeutiques, Département biostatistiques et modélisation pour la santé et l'environnement [LBBE], Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS), VIGNAL, Alexine, Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), and Centre Hospitalier Régional Universitaire de Tours (CHRU Tours)-Université Francois Rabelais [Tours]

Subjects
medicine.medical_specialty, [SDV.SP.MED] Life Sciences [q-bio]/Pharmaceutical sciences/Medication, Treatment outcome, Pharmacology toxicology, MEDLINE, Placebo, 030226 pharmacology & pharmacy, Dizziness, MESH: Dizziness, law.invention, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, [SDV.SP.MED]Life Sciences [q-bio]/Pharmaceutical sciences/Medication, law, Leucine, Vertigo, otorhinolaryngologic diseases, MESH: vertigo, Medicine, Humans, Pharmacology (medical), 030212 general & internal medicine, Medical prescription, Randomized Controlled Trials as Topic, Pharmacology, Randomised controlled trial, Acetylleucine, biology, business.industry, General Medicine, biology.organism_classification, 3. Good health, Physical therapy, MESH: Treatment outcome, MESH: Randomised controlled trial, business, MESH: Acetylleucine, medicine.drug
Abstract

International audience; PURPOSE:To assess the efficacy of acetylleucine to improve or stop an attack of vertigo and dizziness (vertigo/dizziness).METHODS:Systematic review by 2 independent reviewers. Consultation of the Medline, Cochrane and ClinicalTrials.gov databases until September 2018. Keywords used: Acetylleucine, Tanganil®, Acetyl-DL-leucine, Acetyl-leucine. Trial selection: randomised controlled trials (RCTs) comparing acetylleucine against placebo.RESULTS:Up until 2018, no RCTs have been published on the efficacy of acetylleucine in vertigo/dizziness.CONCLUSION:There is no solid evidence of the efficacy of acetylleucine in vertigo/dizziness. Given its frequent prescription and the cost generated for the French social security system, high-quality randomised trials should be carried out to assess its efficacy.

Published
2019
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2. Somaesthetic perception of the vertical in spinal cord injured patients: a clinical study

Author

R. Joassin, Julien Barra, Dominic Pérennou, A. Marquer, V. Bonniaud, Bases Génétiques, Moléculaires et Cellulaires du Développement (BGMCD), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Santé, Plasticité, Motricité (TIMC-IMAG-SPM), Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525 (TIMC-IMAG), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), and Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Male, Somesthésie, genetic structures, MESH: Proprioception, Somatosensory system, MESH: Postural Balance, 0302 clinical medicine, Blessés médullaires, Surveys and Questionnaires, Vertigo, Orthopedics and Sports Medicine, Postural Balance, Spinal cord injury, media_common, Spatial representation, Vestibular system, 0303 health sciences, MESH: Middle Aged, biology, Rehabilitation, [SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences, MESH: Posture, Middle Aged, Vertige, medicine.anatomical_structure, Touch Perception, Somatosensory inputs, Female, MESH: Somatosensory Disorders, Vestibule, Labyrinth, Psychology, Verticale subjective, Adult, medicine.medical_specialty, media_common.quotation_subject, Posture, MESH: Space Perception, MESH: Paraplegia, Représentation spatiale, 03 medical and health sciences, Physical medicine and rehabilitation, Perception, medicine, Subjective vertical, Humans, MESH: Spinal Cord Injuries, Spinal Cord Injuries, 030304 developmental biology, Paraplegia, MESH: Humans, MESH: Questionnaires, MESH: Adult, Proprioception, medicine.disease, biology.organism_classification, Spinal cord, Trunk, MESH: Male, MESH: Vertigo, Somatosensory evoked potential, Space Perception, Somatosensory Disorders, MESH: Vestibule, Labyrinth, Neuroscience, MESH: Female, 030217 neurology & neurosurgery, MESH: Touch Perception
Abstract

French version available; International audience; PURPOSE: The perception of verticality results from the integration of vestibular, visual and somatosensory information. Spinal cord injured patients with complete paraplegia have total somatosensory deafferentation below a certain metameric segment. In our study, we were interested in the implication of somatosensory signal in the construction of verticality and in the possible effect of somatosensory loss on spatial representation. METHOD: We analysed haptic and postural aspects of perceived verticality in 14 spinal cord injured patients with complete paraplegia and in an age- and gender-matched group of 13 controls. We also conducted a structured interview on the existence of vertigo or postural instability in daily life. RESULTS: The spinal cord injured patients perceived verticality without any significant directional bias in the orientation of the vertical but with a greater uncertainty than control subjects, both in haptic and postural modalities. If paraplegic did not report vertigo, half described an altered spatial perception without vision. CONCLUSION: The present results confirm the importance of sensory input from the trunk and the lower limbs in the perception of the vertical. However, visual and vestibular information appear to compensate for somatosensory deafferentation.

Published
2010
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3. Mental representation of space in vestibular patients with otolithic or rotatory vertigo

Author

Marie-José Esteve Fraysse, Olivier Deguine, Gilles Clément, Centre de recherche cerveau et cognition (CERCO), Institut des sciences du cerveau de Toulouse. (ISCT), Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Service d'Oto-Rhino-Laryngologie et d'otoneurochirurgie, Hôpital Purpan [Toulouse], CHU Toulouse [Toulouse]-CHU Toulouse [Toulouse], and Marlot, Catherine

Subjects
Male, MESH: Illusions, Audiology, 0302 clinical medicine, Vertigo, MESH: Otolithic Membrane, Gravity Sensing, Otolith, media_common, Vestibular system, MESH: Aged, MESH: Middle Aged, biology, General Neuroscience, 05 social sciences, Cognition, Middle Aged, Illusions, medicine.anatomical_structure, MESH: Young Adult, Female, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Psychology, Adult, medicine.medical_specialty, MESH: Gravity Sensing, media_common.quotation_subject, MESH: Space Perception, Illusion, 050105 experimental psychology, Otolithic Membrane, Young Adult, 03 medical and health sciences, medicine, otorhinolaryngologic diseases, Humans, 0501 psychology and cognitive sciences, [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Aged, MESH: Humans, Optical illusion, Perspective (graphical), MESH: Adult, biology.organism_classification, MESH: Male, MESH: Vertigo, Space Perception, Mental representation, sense organs, Neuroscience, MESH: Female, 030217 neurology & neurosurgery
Abstract

International audience; In previous studies, we had observed that the occurrence of geometric illusions was reduced when healthy observers were tilted relative to gravity or placed in microgravity. We hypothesized that the alteration of the gravitational (otolith) input was responsible for this change, presumably because of a connection between vestibular and visual-spatial cognitive functions. In this study, we repeated these experiments in vestibular patients who presented signs of otolith disorders. In agreement with the microgravity data, geometric illusions based on horizontal, vertical, and oblique lines were less frequent in patients with otolithic (nonrotatory) vertigo than in patients with rotatory vertigo and in healthy participants. Other visual illusions not based on perspective were not significantly different across all participant groups. We conclude that the impairment in the processing of gravitational input in the otolithic patients could be at the origin of a deformed mental representation of personal and extrapersonal space.

Published
2009

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