1. Alkaloids as chemotaxonomic markers from the Philippine endemic Uncaria perrottetii and Uncaria lanosa f. philippinensis
- Author
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Mario A. Tan, Kurt A. Sy, Grecebio Jonathan D. Alejandro, Christian V. Villanueva, and Jay Edneil C. Olivar
- Subjects
Multidisciplinary ,Traditional medicine ,010405 organic chemistry ,Speciophylline ,Uncarine A ,Biology ,biology.organism_classification ,01 natural sciences ,Uncarine E ,0104 chemical sciences ,010404 medicinal & biomolecular chemistry ,chemistry.chemical_compound ,Uncaria ,chemistry ,Phytochemical ,Uncaria lanosa ,Oxindole ,lcsh:Science (General) ,Mitraphylline ,lcsh:Q1-390 - Abstract
Phytochemical investigation on the aerial parts of Uncaria perrottetii led to the isolation of three pentacyclic oxindole alkaloids uncarine A or isoformosanine (1), uncarine E or isopteropodine (2), and rauniticine-allo-oxindole A (3). Five oxindole alkaloids, isomitraphylline (4), mitraphylline (5), uncarine B or formosanine (6), uncarine F (7), corynoxine (8), and uncarine D or speciophylline (9), were isolated from the leaves of Uncaria lanosa f. philippinensis. Their structures were determined by spectroscopic techniques and in comparison with the literature data. These compounds proved to be important chemotaxonomic markers in the genus Uncaria. Keywords: Rubiaceae, Uncaria, Oxindole alkaloids, Chemotaxonomy, Uncarine
- Published
- 2018