1. Three new prenylated xanthones from Comastoma pedunculatum and their anti-tobacco mosaic virus activity
- Author
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Neng-Jun Xiang, Gan-Peng Li, Qiu-Fen Hu, Min Zhou, Ji Bingkun, Ying-Liang Zhao, Li-Mei Li, Tian-Dong Zhang, Wei Dong, Jie Lou, Kun Zhou, and Yue-de Wang
- Subjects
Mosaic virus ,Stereochemistry ,Comastoma pedunculatum ,Substituent ,Plant Science ,Biology ,Biochemistry ,chemistry.chemical_compound ,Prenylation ,chemistry ,Tobacco mosaic virus ,Organic chemistry ,Agronomy and Crop Science ,Two-dimensional nuclear magnetic resonance spectroscopy ,Biotechnology - Abstract
Comastomaxanthones A–C ( 1 – 3 ), three new xanthones with a rare 2-oxoprenyl substituent, along with three known ones ( 4 – 6 ) were isolated from the aerial parts of Comastoma pedunculatum . Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. In addition, compounds 1 – 6 were tested for their anti-tobacco mosaic virus activity. The results showed that all isolated compounds exhibited weak anti-TMV activity with IC 50 values ranging from 122.7 to 242.9 μM.
- Published
- 2015
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