1. Adaptor proteins GIR1 and GIR2. I. Interaction with the repressor GLABRA2 and regulation of root hair development
- Author
-
Renhong Wu and Vitaly Citovsky
- Subjects
0301 basic medicine ,Mutant ,Biophysics ,Arabidopsis ,Repressor ,Plasma protein binding ,Root hair ,Biochemistry ,Plant Roots ,Article ,03 medical and health sciences ,Gene Expression Regulation, Plant ,Molecular Biology ,Phylogeny ,Adaptor Proteins, Signal Transducing ,Genetics ,Homeodomain Proteins ,biology ,Arabidopsis Proteins ,Gene Expression Profiling ,Signal transducing adaptor protein ,Cell Biology ,biology.organism_classification ,Cell biology ,Gene expression profiling ,030104 developmental biology ,Function (biology) ,Protein Binding - Abstract
Plants use specialized root outgrowths, termed root hairs, to enhance acquisition of nutrients and water, help secure anchorage, and facilitate interactions with soil microbiome. One of the major regulators of this process is GLABRA2 (GL2), a transcriptional repressor of root hair differentiation. However, regulation of the GL2-function is relatively well characterized, it remains completely unknown whether GL2 itself functions in complex with other transcriptional regulators. We identified GIR1 and GIR2, a plant-specific two-member family of closely related proteins that interact with GL2. Loss-of-function mutants of GIR1 and GIR2 enhanced development of root hair whereas gain-of-function mutants repressed it. Thus, GIR1 and GIR2 might function as adaptor proteins that associate with GL2 and participate in control of root hair formation.
- Published
- 2017