Search

Your search keyword '"Lorna W. Harries"' showing total 91 results

Search Constraints

Start Over You searched for: Author "Lorna W. Harries" Remove constraint Author: "Lorna W. Harries" Topic biology Remove constraint Topic: biology
91 results on '"Lorna W. Harries"'

Search Results

1. Islet-expressed circular RNAs are associated with type 2 diabetes status in human primary islets and in peripheral blood

2. Negligible senescence in naked mole rats may be a consequence of well-maintained splicing regulation

3. A biallelic SNIP1 Amish founder variant causes a recognizable neurodevelopmental disorder

4. Changes to the identity of EndoC-βH1 beta cells may be mediated by stress-induced depletion of HNRNPD

5. circRNAs expressed in human peripheral blood are associated with human aging phenotypes, cellular senescence and mouse lifespan

6. Astrocyte senescence may drive alterations in GFAPα, CDKN2A p14ARF, and TAU3 transcript expression and contribute to cognitive decline

7. Cellular stressors may alter islet hormone cell proportions by moderation of alternative splicing patterns

8. Extreme longevity variants at the FOXO3 locus may moderate FOXO3 isoform levels

9. Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence

10. FOXO1 and ETV6 genes may represent novel regulators of splicing factor expression in cellular senescence

11. Human longevity: 25 genetic loci associated in 389,166 UK biobank participants

12. Splicing regulatory factors, ageing and age-related disease

13. Dietary restriction in ILSXISS mice is associated with widespread changes in splicing regulatory factor expression levels

14. To help aging populations, classify organismal senescence

15. Author response: Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer

16. Alternative splicing in serotonergic system: Implications in neuropsychiatric disorders

17. miRNAs responsive to the diabetic microenvironment in the human beta cell line EndoC-βH1 may target genes in the FOXO, HIPPO and Lysine degradation pathways

18. The transcript expression levels of HNRNPM, HNRNPA0 and AKAP17A splicing factors may be predictively associated with ageing phenotypes in human peripheral blood

19. Androgen-regulated transcription ofESRP2drives alternative splicing patterns in prostate cancer

20. Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer

21. Functional characterisation of ADIPOQ variants using individuals recruited by genotype

22. Peripheral Blood Transcriptomic Signatures of Fasting Glucose and Insulin Concentrations

23. Physiological effects of Type 2 diabetes on mRNA processing and gene expression

24. Comparison of senescence-associated miRNAs in primary skin and lung fibroblasts

25. An ABCC8 nonsense mutation causing neonatal diabetes through altered transcript expression

26. Targeted Allelic Expression Profiling in Human Islets Identifies cis-Regulatory Effects for Multiple Variants Identified by Type 2 Diabetes Genome-Wide Association Studies

27. Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease

28. The biology of ageing and the omics revolution

30. A dynamical systems model for the measurement of cellular senescence

31. Expression Profiling of Type 2 Diabetes Susceptibility Genes in the Pancreatic Islets, Adipose Tissue and Liver of Obese Mice

32. A rare SNP in pre-miR-34a is associated with increased levels of miR-34a in pancreatic beta cells

33. Associations between PFOA, PFOS and changes in the expression of genes involved in cholesterol metabolism in humans

34. Gene Expression Biomarkers and Longevity

35. Expression profiling of putative type 2 diabetes susceptibility genes in human islets and in rat beta cell lines

36. Permanent neonatal diabetes due to paternal germline mosaicism for an activating mutation of the KCNJ11 Gene encoding the Kir6.2 subunit of the beta-cell potassium adenosine triphosphate channel

37. The DDX6–4E-T interaction mediates translational repression and P-body assembly

38. Advancing age is associated with gene expression changes resembling mTOR inhibition: Evidence from two human populations

39. MicroRNA expression profiling of human islets from individuals with and without Type 2 diabetes: promises and pitfalls

40. Genomics and Successful Aging: Grounds for Renewed Optimism?

41. Changes in inflammatory gene expression induced by hyperbaric oxygen treatment in human endothelial cells under chronic wound conditions

42. CCAAT-enhancer-binding protein-beta expression in vivo is associated with muscle strength

43. Allelic heterogeneity and more detailed analyses of known loci explain additional phenotypic variation and reveal complex patterns of association

44. Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing

45. An unusual case of cyclin-D1-positive peripheral T cell lymphoma with a 11:14 translocation

46. Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis

47. Evaluation of 13q14 Status in Multiple Myeloma by Digital Single Nucleotide Polymorphism Technology

48. Update of mutations in the genes encoding the pancreatic beta-cell KATPchannel subunits Kir6.2 (KCNJ11) and sulfonylurea receptor 1 (ABCC8) in diabetes mellitus and hyperinsulinism

49. Mosaic Paternal Uniparental Isodisomy and an ABCC8 Gene Mutation in a Patient With Permanent Neonatal Diabetes and Hemihypertrophy

50. Partial and whole gene deletion mutations of the GCK and HNF1A genes in maturity-onset diabetes of the young

Catalog

Books, media, physical & digital resources