1. Petrosia ficiformis (Poiret, 1789): an excellent model for holobiont and biotechnological studies
- Author
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Laura Steindler, Marco Giovine, and Carlo Cerrano
- Subjects
Marine sponges ,Biomedical Engineering ,microbiome ,Bioengineering ,Petrosia ,eukaryotic cell ,prokaryotic cell ,Animals ,Microbiome ,Symbiosis ,Phylogeny ,nonhuman ,biology ,human cell ,three dimensional cell culture ,biology.organism_classification ,Porifera ,Holobiont ,symbiont ,Sponge ,Evolutionary biology ,eukaryotic cell, human cell, microbial community, microbiome, nonhuman, Petrosia, prokaryotic cell, symbiont, three dimensional cell culture ,Adaptation ,microbial community ,Petrosia ficiformis ,Biotechnology - Abstract
The aggregation of prokaryotic and eukaryotic cells has resulted in evolution of organisms with remarkable abilities to synthetize natural bioactive compounds of biotechnological relevance. Marine sponges such as Petrosia ficiformis are examples of this evolutionary strategy. The P. ficiformis microbiome, which produces a diversity of chemical compounds, plays a fundamental role in this sponge's extraordinary adaptation to various ecological conditions. The microbial community of P. ficiformis seems representative of sponge microbiomes, but it has an unusual exclusively horizontal transmission. This uncommon feature, together with its wide environmental distribution, its ability to generate 3D cell cultures that host symbionts, and the availability of meta-omics and physiology information make this sponge an effective model to study the complexity of holobionts.
- Published
- 2022