1. Role of plant-based diet in late-life cognitive decline: results from the Salus in Apulia Study
- Author
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Rossella Donghia, Francesco Panza, Ilaria Bortone, Petronilla Battista, Giovanni De Pergola, Luisa Lampignano, Chiara Griseta, Fabio Castellana, Madia Lozupone, Vito Guerra, Gianluigi Giannelli, Rodolfo Sardone, Roberta Zupo, and Heiner Boeing
- Subjects
0301 basic medicine ,Mediterranean diet ,Population ,Medicine (miscellaneous) ,Biology ,Diet, Mediterranean ,Eating ,03 medical and health sciences ,Cognition ,0302 clinical medicine ,Consistency (negotiation) ,medicine ,Humans ,Dementia ,Cognitive Dysfunction ,Cognitive decline ,education ,Aged ,education.field_of_study ,030109 nutrition & dietetics ,Nutrition and Dietetics ,Diet, Vegetarian ,General Neuroscience ,General Medicine ,Micronutrient ,medicine.disease ,Diet ,Population study ,030217 neurology & neurosurgery ,Demography - Abstract
Consistency among population-based studies investigating the relationship between diet and cognition in older inhabitants in the Mediterranean area is poor. The present study investigated whether diet changes over 12 years were associated with cognitive function in older people in Southern-Italy.From the 'Salus in Apulia Study', that includes the MICOL and GreatAGE Studies, 584 participants were selected, firstly enrolled in MICOL3 (M3) and later in the GreatAGE Study (MICOL4, M4). Foods and micronutrients intake were recorded in both studies, and global cognitive function in M4, assessed with the Mini Mental State Examination.Plant-based foods, particularly coffee and vegetables, as well as vitamin A sources, were inversely associated to age-related cognitive impairment. Alcohol consumption showed a detrimental role on cognition, while red meat appeared to be beneficial in the present study, although its role is traditionally considered harmful for cognitive function.Our study confirmed that a traditional Mediterranean dietary pattern based on agricultural products and low alcohol consumption may help to prevent/delay age-related cognitive impairment.
- Published
- 2021