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Your search keyword '"D. E. Teuwen"' showing total 2 results
Start Over Author "D. E. Teuwen" Topic biology
2 results on '"D. E. Teuwen"'

1. A trial of RIT-4237 rotavirus vaccine in 1-month-old infants

Author

J. Deutsch, C.-H. Kunz, I. D. Mutz, D. E. Teuwen, and F. Krainer

Subjects
Rotavirus, Pediatrics, medicine.medical_specialty, Reoviridae, Placebo, medicine.disease_cause, Vaccines, Attenuated, Rotavirus Infections, Young infants, Double blind, Placebos, Random Allocation, fluids and secretions, Double-Blind Method, Medicine, Humans, Clinical Trials as Topic, biology, business.industry, Infant, Newborn, Rotavirus Vaccines, Infant, Viral Vaccines, biology.organism_classification, Rotavirus vaccine, Gastroenteritis, Antibody response, Immunization, Immunoglobulin M, Pediatrics, Perinatology and Child Health, Immunology, Antibody Formation, business
Abstract

In a double blind placebo-controlled study rotavirus vaccine RIT 4237 was offered to young infants after the fourth week of life. The vaccine was very well tolerated. Fifty-seven out of 100 vaccine recipients and 10 out of 103 placebo recipients developed rotavirus-IgM-antibodies during the 1 month follow-up period. During a 6 month follow-up, stool samples from 2 out of 12 vaccinees and from 5 out of 12 placebo recipients contained rotavirus.

Published
1989

2. Response to RIT 4237 oral rotavirus vaccine in human milk, adapted-and soy-formula fed infants

Author

K. Pittschieler, F. Mantovanelli, A. Delem, G Zoppi, and D. E. Teuwen

Subjects
Male, Rotavirus, Administration, Oral, medicine.disease_cause, Antibodies, Viral, Vaccines, Attenuated, Immunoglobulin G, medicine, Humans, Infant Nutritional Physiological Phenomena, biology, Milk, Human, Tetanus, business.industry, Diphtheria, Rotavirus Vaccines, Infant, Viral Vaccines, General Medicine, medicine.disease, Rotavirus vaccine, Vaccination, Immunization, Immunoglobulin M, Pediatrics, Perinatology and Child Health, Immunology, biology.protein, Female, Infant Food, Soybeans, business
Abstract

During the first month of life 28 full-term newborns were breast-fed (18 males and 11 females). Thereafter 8 infants continued breast-feeding while the remainder were randomly fed on either an adapted milk formula (n=13) or a soy-formula (n=7). At five months, after an oral dose of RIT 4237 rotavirus vaccine of bovine origin was given, growth and IgM/IgG type antibodies against rotavirus were measured. Weight gain was similar in all infants. There were 2 IgM and 1 IgG responders out of 7 soy fed infants, compared with 4 out of 8 human milk fed (both IgM and IgG) and 7 out of 13 IgM and 6/12 IgG formula fed infants responding to vaccination. This observation confirms previous results obtained with polio, diphtheria tetanus and pertussis vaccines indicating that soy-protein formulas may interfere with immunization processes.

Published
1989

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