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42 results on '"Colin A. McKenzie"'

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1. Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

2. Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

3. A cross-sectional clinic-based study exploring whether variants within the glutathione S-transferase, haptoglobin and uridine 5′-diphospho-glucuronosyltransferase 1A1 genes are associated with interindividual phenotypic variation in sickle cell anaemia in

4. Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci

5. A multi-ancestry genome-wide study incorporating gene–smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

6. Exploring putative genetic determinants of inter-individual phenotypic heterogeneity in sickle cell disease: A cross-sectional Jamaican cohort-based study

7. A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

8. A Cross-sectional Clinic-based Study Exploring whether Variants within Genes Coding for Enzymes of the Transmethylation and Trans-sulphuration Pathways Are Associated with Inter-individual Phenotypic Variation in Sickle Cell Anaemia in Jamaica

9. Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations

10. Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

11. Common variants associated with plasma triglycerides and risk for coronary artery disease

12. Quantitative Variation in Plasma Angiotensin-I Converting Enzyme Activity Shows Allelic Heterogeneity in theABOBlood Group Locus

13. Discovery and refinement of loci associated with lipid levels

14. Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

15. The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

16. Correction: Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations

17. Genome-wide association of anthropometric traits in African- and African-derived populations

18. Childhood malnutrition is associated with a reduction in the total melanin content of scalp hair

19. New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

20. SNP Haplotypes in the Angiotensin I-Converting Enzyme (ACE) Gene: Analysis of Nigerian Family Data Using Gamete Competition Models

21. Angiotensin-Converting EnzymeGene Polymorphisms and Obesity: An Examination of Three Black Populations

22. Lipid-related genes and myocardial infarction in 4685 cases and 3460 controls: discrepancies between genotype, blood lipid concentrations, and coronary disease risk

23. Angiotensin I-converting enzyme polymorphisms, ACE level and blood pressure among Nigerians, Jamaicans and African-Americans

24. Localization of a Small Genomic Region Associated with Elevated ACE

25. Large-scale test of hypothesised associations between the angiotensin-converting-enzyme insertion/deletion polymorphism and myocardial infarction in about 5000 cases and 6000 controls

26. The efficacy of detecting variants with small effects on the Affymetrix 6.0 platform using pooled DNA

27. A preliminary examination of the effects of genetic variants of redox enzymes on susceptibility to oedematous malnutrition and on percentage cytotoxicity in response to oxidative stress in vitro

28. Association of common DNA sequence variants at 33 genetic loci with blood lipids in individuals of African ancestry from Jamaica

29. Fine mapping of the association with obesity at the FTO locus in African-derived populations

30. Genetic variation on chromosome 6 influences F cell levels in healthy individuals of African descent and HbF levels in sickle cell patients

31. A genome-wide search replicates evidence of a quantitative trait locus for circulating angiotensin I-converting enzyme (ACE) unlinked to the ACE gene

32. Predicted declines in sickle allele frequency in Jamaica using empirical data

33. Polymorphisms in genes involved in folate metabolism as risk factors for oedematous severe childhood malnutrition: a hypothesis-generating study

34. The frequency of the sickle allele in Jamaica has not declined over the last 22 years

35. Trans-ethnic fine mapping of a quantitative trait locus for circulating angiotensin I-converting enzyme (ACE)

36. Phenotypic Expression of Melanocortin-1 Receptor Mutations in Black Jamaicans

37. Genome-Wide Association Study of Coronary Heart Disease and Its Risk Factors in 8,090 African Americans: The NHLBI CARe Project

38. Rapid Assessment of Genetic Ancestry in Populations of Unknown Origin by Genome-Wide Genotyping of Pooled Samples

39. Fine-mapping of an ancestral recombination breakpoint in DCP1

40. Genetic variation in APOL1 and MYH9 genes is associated with chronic kidney disease among Nigerians

41. Glutathione S-transferase polymorphisms may be associated with risk of oedematous severe childhood malnutrition

42. Classical sickle beta-globin haplotypes exhibit a high degree of long-range haplotype similarity in African and Afro-Caribbean populations

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